Synergistic Integration of Aggregation-Induced Emission and FRET Mechanisms in Conjugated Polymers via Molecular Engineering for Ultrasensitive, Rapid, and Discriminative Detection of Perfluoroalkyl Substances
Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 2, 2025
The
global
contamination
of
water
bodies
by
persistent
organic
pollutants
(perfluoroalkyl
substances
(PFAS))
has
generated
significant
societal
concern,
emphasizing
the
urgent
need
for
smart
strategies
their
rapid,
ultratrace,
and
on-site
detection.
Conjugated
polymers
(CPs)
are
exceptional
fluorescence
sensing
materials
with
signal-amplification
properties,
yet
performance
is
often
hindered
a
conventional
aggregation-caused
quenching
(ACQ)
effect.
Herein,
we
present
two
acceptor-engineered
aggregation-induced
emission
(AIE)-active
CPs
(FTD-MI
FTD-C8-MI)
integrated
efficient
Förster
resonance
energy
transfer
(FRET)
mechanisms
ultralow
detection
PFAS.
FTD-MI
exhibits
turn-off
(cyan
to
dark)
response,
while
FTD-C8-MI
shows
ratiometric
red)
response
PFAS
due
synergistic
effect
AIE
interchain
FRET,
facilitated
electrostatic
hydrophobic
interactions
upon
binding.
Both
demonstrate
excellent
sensitivity
at
subnanomolar
level
toward
most
abundant
PFAS,
perfluorooctanoic
acid
(PFOA),
perfluorooctanesulfonic
(PFOS).
mechanism
been
thoroughly
investigated
both
experimental
simulation
studies.
Additionally,
an
optical
sensor
array
coupled
machine
learning
algorithms
established
discriminative
six
types
Finally,
portable
smartphone
platform
custom-designed
"app"
was
developed
real-time,
on-site,
semiquantitative
analysis
in
actual
samples.
Thus,
providing
sensitive,
portable,
cost-effective,
user-friendly
solution,
this
work
offers
powerful
tool
monitoring
pollution,
ensuring
safety,
reducing
risks
public
health.
Language: Английский
Fluorescent Sodium Alginate Hydrogel–Carbon Dots Sensor for Detecting Perfluorooctanoic Acid in Potable Water
Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 3, 2025
Per-
and
polyfluoroalkyl
substances
(PFASs),
especially
perfluorooctanoic
acid
(PFOA),
are
emerging
environmental
health
concerns
due
to
their
persistence,
resistance
degradation,
bioaccumulation.
In
this
study,
we
developed
a
sensitive
selective
detection
platform
based
on
sodium
alginate
(SA)
hydrogel
modified
with
nitrogen
fluorinated
carbon
dots
(N,F-CDs)
enhance
the
of
PFOA
in
natural
engineered
water
systems.
The
SA
hydrogel-N,F-CD
composite
exhibited
strong
fluorescence
at
480
nm
after
optimization,
achieving
limit
as
low
0.001
ppt.
sensor
was
characterized
by
using
Scanning
Electron
Microscopy
(SEM),
Fourier-Transform
Infrared
Spectroscopy
(FT-IR),
Powder
X-ray
Diffraction
(PXRD),
Photoelectron
(XPS),
zeta
potential
spectroscopy,
revealing
its
structural
integrity,
functional
groups,
surface
charge
hydrogel-N,F-CDs
network.
Sensitivity
assessments
demonstrated
linear
response
concentrations
ranging
from
1
66
ppq.
Selectivity
tests
confirmed
sensor's
ability
distinguish
other
perfluorinated
compounds,
minimal
interference
substances.
practical
applicability
validated
spiked
recovery
experiments
tap
samples
various
locations,
rates
between
94%
106.6%.
This
offers
reliable,
efficient,
highly
for
PFAS,
demonstrating
real-world
PFAS-monitoring
applications.
Language: Английский