Progress in electrochemiluminescence of metal nanoclusters DOI Open Access
Xiaojian Wang, Kaiyang Kuang, Mengmeng Jing

et al.

Chemical Physics Reviews, Journal Year: 2024, Volume and Issue: 5(4)

Published: Dec. 1, 2024

Metal nanoclusters (NCs) composed of metal atoms and ligands show promise as electrochemiluminescent (ECL) materials due to their optical electrochemical properties. This review provides a comprehensive overview the ECL mechanisms, advantages, roles NCs luminophores, catalysts, quenchers, substrates, carriers. Insights into factors that influence in will lay foundation for future research. In addition, applications metallic NC-based detection platforms are summarized, potential research directions presented.

Language: Английский

Amplified electrochemiluminescence of Ru(dcbpy)32+ via coreactant active sites on nitrogen-doped graphene quantum dots DOI

Lingyue Guo,

Libo Li, Lijun Luo

et al.

Talanta, Journal Year: 2025, Volume and Issue: 286, P. 127554 - 127554

Published: Jan. 13, 2025

Language: Английский

Citations

0

Nanomaterials-Integrated CRISPR/Cas Systems: Expanding the Toolbox for Optical Detection DOI
Tianying Sun, Weiwei He, Xiangmei Chen

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Nanomaterials-integrated CRISPR/Cas systems have rapidly emerged as powerful next-generation platforms for optical biosensing. These integrated harness the precision of CRISPR/Cas-mediated nucleic acid detection while leveraging unique properties nanomaterials to achieve enhanced sensitivity and expanded analytical capabilities, thereby broadening their diagnostic potential. By incorporating a diverse range nanomaterials, these effectively expand toolbox detection, offering adaptable solutions tailored various challenges. This review provides comprehensive overview successfully into CRISPR/Cas-based sensing systems. It examines multiple modalities, including fluorescence, electrochemiluminescence, colorimetry, surface-enhanced Raman spectroscopy, highlighting how facilitate signal amplification, enable multiplexing, support development point-of-care applications. Additionally, practical applications in critical fields such healthcare diagnostics environmental monitoring are showcased. While offer considerable advantages, several real-world challenges complexity assay workflows, impact cost, regulatory hurdles must be addressed before widespread implementation can achieved. identifying obstacles proposing strategic solutions, we aim pave way continued advancement adoption nanomaterial-integrated biosensing technologies.

Language: Английский

Citations

0

Development and application of DNA hydrogels in biosensing: Current status and future implications DOI
Zhuo Chen, Kang Mao, Jianzhi Xue

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113664 - 113664

Published: April 1, 2025

Language: Английский

Citations

0

Electrochemiluminescence Biosensor Based on an Efficient Antifouling Cell Membrane Hydrogel for the Direct Detection of Alkaline Phosphatase in Human Serum and Cell Lysate DOI

Qiongwei Wu,

Zhengjun Dong,

Fan Geng

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 19, 2025

Electrochemiluminescence (ECL) biosensors are an ideal choice for the real-time and sensitive detection of biomarkers. However, there many interfering biomolecules in human serum or cell lysate that can affect ECL signal through nonspecific interface adsorption. To solve this issue, efficient antifouling biosensor based on a red blood membrane (RBCM) hydrogel was developed direct alkaline phosphatase (ALP) lysate. Among them, RBCM prepared by embedding purified vesicles into [1,2-distearoyl-sn-glycerol-3-phosphoethanolamine]-[polyethylene]-[acrylamide] (DSPE-PEG-AM), which endowed with high stability biocompatibility. Meanwhile, compared to RBCM, constructed improved electron transfer rate interface. Furthermore, luminescent copper nanosheets (Cu NSs) quencher MnO2 NSs were encapsulated hydrogel, greatly reduced distance between Cu NSs, thereby effectively improving quenching efficiency. In presence ALP, l-ascorbic acid 2-phosphate trisodium salt hydrolyzed ascorbic acid, thus disrupting structure restore signal. Based above sensing strategies, achieved ultrasensitive ALP wide linear range (10-5 104 U·L-1) limit as low 3.4 × 10-6 U·L-1 (3δ/k), demonstrating potential application value clinical diagnosis.

Language: Английский

Citations

0

Progress in electrochemiluminescence of metal nanoclusters DOI Open Access
Xiaojian Wang, Kaiyang Kuang, Mengmeng Jing

et al.

Chemical Physics Reviews, Journal Year: 2024, Volume and Issue: 5(4)

Published: Dec. 1, 2024

Metal nanoclusters (NCs) composed of metal atoms and ligands show promise as electrochemiluminescent (ECL) materials due to their optical electrochemical properties. This review provides a comprehensive overview the ECL mechanisms, advantages, roles NCs luminophores, catalysts, quenchers, substrates, carriers. Insights into factors that influence in will lay foundation for future research. In addition, applications metallic NC-based detection platforms are summarized, potential research directions presented.

Language: Английский

Citations

1