Luminescence,
Journal Year:
2025,
Volume and Issue:
40(2)
Published: Feb. 1, 2025
The
development
of
multifunctional
biomaterials
holds
paramount
importance
in
advancing
biomedical
research
and
applications.
This
investigation
focuses
on
synthesizing
cerium/reduced
graphene
oxide
(Ce/RGO)
nanocomposites
using
a
hydrothermal
approach.
Structural
evaluations
via
XRD
Raman
spectroscopy
confirm
the
successful
conversion
(GO)
to
rGO
integration
cerium
nanoparticles
onto
surface.
FTIR
further
validates
structural
alterations
adhesion
nanoparticles.
Morphological
elemental
analyses
performed
FE-SEM
EDAX
demonstrate
attachment
sheets.
Enhanced
hardness
Ce/rGO
samples,
compared
with
pure
rGO,
as
indicated
by
Vickers
testing,
suggests
improved
mechanical
properties
because
existence
Measurements
water
contact
angle
show
reduced
hydrophobicity
Ce-rGO
implying
enhanced
wettability
upon
nanoparticle
integration.
Additionally,
porosity
analysis
reveals
increased
facilitating
nutrient
transfer
within
system.
Biocompatibility
assessments,
including
hemolytic
activity
testing
Vero
cell
viability
tests
favorable
biocompatibility
samples
rGO.
Antibacterial
studies
unveil
efficacy
against
S.
aureus
E.
coli
attributed
synergistic
effects
rGO's
antimicrobial
nanoparticles'
activity.
study
highlights
encouraging
potential
nanostructures
for
applications,
offering
distinct
properties,
hydrophilicity,
biological
interactions,
antibacterial
performance.
Biosensors,
Journal Year:
2025,
Volume and Issue:
15(1), P. 63 - 63
Published: Jan. 19, 2025
The
sensitive
detection
of
inflammatory
biomarkers
in
gingival
crevicular
fluid
(GCF)
is
highly
desirable
for
the
evaluation
periodontal
disease.
Luminol-based
electrochemiluminescence
(ECL)
immunosensors
offer
a
promising
approach
fast
and
convenient
biomarkers.
However,
luminol’s
low
ECL
efficiency
under
neutral
conditions
remains
challenge.
This
study
developed
an
immunosensor
by
engineering
immunorecognition
interface
on
outer
surface
mesoporous
silica
nanochannel
film
(SNF)
confining
Co3O4
nanocatalyst
within
SNF
nanochannels
to
improve
luminol
efficiency.
was
grown
indium
tin
oxide
(ITO)
electrode
using
simple
Stöber
solution
growth
method.
A
successfully
confined
through
situ
electrodeposition,
confirmed
X-ray
photoelectron
spectroscopy
(XPS)
electrochemical
measurements.
demonstrated
excellent
electrocatalytic
activity,
effectively
enhancing
H2O2
oxidation
boosting
signal
conditions.
Using
interleukin-6
(IL-6)
as
proof-of-concept
demonstration,
epoxy
functionalization
enabled
covalent
immobilization
capture
antibodies,
forming
specific
interface.
IL-6
binding
induced
immunocomplex
formation,
which
reduced
allowed
quantitative
detection.
showed
linear
range
from
1
fg
mL−1
10
ng
mL−1,
with
limit
(LOD)
0.64
mL−1.
It
also
good
selectivity
anti-interference
capabilities,
enabling
successful
artificial
GCF
samples.
Luminescence,
Journal Year:
2025,
Volume and Issue:
40(2)
Published: Jan. 31, 2025
ABSTRACT
A
novel
fluorescence‐based
sensor
has
been
developed
for
the
sensitive
detection
of
malathion,
an
organophosphorus
pesticide,
using
sulfur‐doped
quantum
dots
(SQDs)
embedded
within
graphitic
carbon
nitride
(g‐C₃N₄)
nanosheets.
The
SQDs
were
synthesized
through
a
hydrothermal
method,
whereas
g‐C₃N₄
nanosheets
produced
via
exfoliation
process.
resulting
SQDs@g‐C₃N₄
nanocomposite
demonstrated
outstanding
performance
malathion
in
food
samples,
exhibiting
wide
linear
range
10–120
μM
and
exceptionally
low
limit
0.02
μM.
This
sensitivity
allows
accurate
rapid
pesticide
monitoring
at
trace
levels.
sensor's
was
optimized
by
varying
experimental
conditions,
ensuring
that
it
provided
high
sensitivity,
excellent
stability,
impressive
selectivity
toward
even
complex
matrices.
Analytical Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 2, 2025
Lomefloxacin
(LOM)
is
an
efficacious
antibiotic
that
might
lead
to
liver
damage
and
other
adverse
reactions
if
consumed
over
extended
period.
Hence,
this
study
proposed
a
DNAzyme-mediated
DNA
walker
as
signal
amplifier
in
combination
with
substantial
quantity
of
Au
nanoparticle
(NP)-loaded
hydrogen-bonded
organic
frameworks
(HOFs)
surface-enhanced
Raman
scattering
(SERS)
substrate
accomplish
the
highly
sensitive
detection
LOM
food.
Crucially,
due
their
high
specific
surface
area
strong
adsorption
capacity,
HOFs
act
ideal
for
situ
growth
large
amount
NPs,
which
exhibit
robust
uniform
SERS
enhancement.
Once
target
was
presented,
DNAzyme
activated
start
produce
single
abundance,
further
triggered
catalytic
hairpin
assembly
(CHA)
cycle.
In
addition,
multi-interstitial
core-shell
structure
Au@Ag@4-nitrobenzenethiol
(4-NTP)@Au@Hp3
produced
more
"hot
spots"
significantly
amplified
local
electromagnetic
field,
HOF@Au
synergistically
strengthening
4-NTP.
Using
principle,
sensor
achieved
ultrasensitive
through
"signal
on"
strategy,
limit
low
4.62
×
10-14
mol/L.
This
strategy
explored
meaningful
innovative
path
design
novel
biosensor
selective
antibiotics
