DNA nanowires-mediated high sensitive quantum dot-fluorescence-linked immunoassay for proteins analysis

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1352, P. 343931 - 343931

Published: March 12, 2025

Language: Английский

Point-of-Care Testing: The Convergence of Innovation and Accessibility in Diagnostics

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

Over the years, evolution of point-of-care testing (POCT) has been driven by technological advancements in materials, design, and artificial intelligence, as well breakthrough developments wearable technologies. These innovations are shifting diagnostics from centralized medical facilities to individual homes, meeting growing demand for personalized healthcare. This Review explores recent binding-based assay technologies over past two focusing on platforms such traditional flow assays (lateral vertical flow), fully integrated microfluidic devices, biosensor-integrated systems POCT applications. It emphasizes role optical electrochemical detection methods, which essential ensuring sensitivity, specificity, reliability required a POCT. offer advantages including ease use, high diagnostic accuracy, rapid clinical assessment, cost-effectiveness manufacturing consumables. Additionally, highlights current challenges future perspectives delivering healthcare through portable that operate sample-in, result-out basis.

Language: Английский

In silico study of a new class of DNA fluorescent probes: docking, molecular dynamics and quantum chemistry calculations

Journal of Molecular Modeling, Journal Year: 2025, Volume and Issue: 31(4)

Published: April 1, 2025

Language: Английский