Salmonella Type III Secretion System Effectors

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2611 - 2611

Published: March 14, 2025

Salmonella is estimated to infect between 200 million and over 1 billion people per year. The exact number not known, as many cases go unreported. Integral the pathogenesis of Salmonella, well numerous other Gram-negative pathogens, its type III effectors. possesses two distinct secretion systems, encoded by pathogenicity island-1 island-2. Together, they secrete at least 49 effectors into host cells that are collectively responsible for virulence attributes this pathogen. These factors facilitate invasion cells, induce attenuate inflammation, change migratory properties infected phagocytes, among things. effects all on discussed.

Language: Английский

Manipulation of host immune defenses by effector proteins delivered from multiple secretion systems of Salmonella and its application in vaccine research

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 14

Published: April 4, 2023

is an important zoonotic bacterial species and hazardous for the health of human beings livestock globally. Depending on host,

Language: Английский