Interactions of Clay Minerals with Biomolecules and Protocells Complex Structures in the Origin of Life: A Review DOI
Ying Yan, Huaming Yang

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 21, 2024

Abstract The origin of life (OoL) has always been a mysterious and challenging topic that puzzles human beings. Clay minerals have unique properties wide distribution in early Earth environments. They can not only adsorb biological small molecules to catalyze their polymerization, but play an active role the formation evolution protocells. In this review, research progress on interactions clay with biomolecules protocells complex structures field OoL based chemical theory is summarized. types, minerals, protocell models related are introduced detail. mechanism interaction between molecules, construction formation, structure stability systematically described. Finally, future priorities challenges discussed. It aspired review further advance exploration from new perspective, also bring some interesting findings ideas interdisciplinary materials, biology, chemistry other disciplines.Clay variety biomolecules, which be used as structural functional templates promote organic synthesis protocells, playing non‐negligible OoL.

Language: Английский

Amphiphilic self-assembled gold nanoparticle plasma vesicles regulate alkaline phosphatase catalysis reaction for nanoreactor DOI

Jiaojiao Su,

Guangyu Wu, Yaning Zhang

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114638 - 114638

Published: May 1, 2025

Language: Английский

Citations

0
Biomineralization‐Inspired Membranization Toward Structural Enhancement of Coacervate Community DOI Creative Commons
Chunyu Zhao, Xiaoliang Wang,

Lianning Li

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 16, 2025

Abstract The design and assembly of protocell models that can mimic the features functions life present a significant research challenge with potential for far‐reaching impact. Inspired by natural phenomenon microbe‐induced mineralization, way is developed to induce spontaneous formation mineralized membrane on surface coacervate droplets utilizing Fe 3+ ions. In particular, effect ions microstructure at molecular level dissected combining theoretical experimental approaches. reversible process be regulated redox reactions involving 2+ /Fe within coacervate. not only enhances stability prevents aggregation coalescence, but also allows adjacent together. membranized assemblages retain inherent properties biomolecule sequestration enzyme catalysis, demonstrate excellent resistance high temperatures pressures as well good over 30 days. This study will offer new platform coacervate‐based life‐like biomimetic systems, enhance understanding interactions underlying various biological phenomena level.

Language: Английский

Citations

0
Spatio‐chemical and spatio‐temporal processes of hierarchical multicompartments: Diffusion‐controlled communication between nano‐ and microcompartments DOI Creative Commons
Dietmar Appelhans, Xin Qiao, Haixu Chen

et al.

Angewandte Chemie International Edition, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Exploring the synergy of feedback behavior and molecular communication between micro- nanocompartments is great implication for development advanced hierarchical living-like materials. Non-covalent interactions are driving forces dynamic temporal events in biomimetic structures. Herein, pH-responsive multi-compartments (HMC) constructed via hydrophobic-hydrophobic azobenzene units phospholipid layers through integration two distinct structural units: phospholipid-membranized coacervates (Coa@DMPC) azobenzene-functionalized polymersomes (Azo-Psomes). This enables us to study spatio-temporal signal pathways pH homeostasis triggering feedback-controlled peroxidase-like Azo-Psomes within HMC. Compared with undocking systems, information transmission process HMC shows a high efficiency. Besides continuous addition nutrients, synchronization different reactions requires spatial loading glucose oxidase L-phenylalanine ammonia lyase or beta-cyclodextrin/hemin complexes Azo-Psomes. exhibit behavior. The membrane responsible activity lumen-integrated Finally, this strategy provides new approach constructing more complex systems by interconnecting at least membrane-containing compartments further explore synergistic mechanisms behaviors among artificial cell communities.

Language: Английский

Citations

0
Construction of hybrid chiral microcompartment of Au NPs grafted penicillamine and BSA-PNIPAAm conjugate with enantiomatically modulated interfacial catalytic efficiency DOI

Jiaojiao Su,

Yaning Zhang,

Mingli Yue

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 143602 - 143602

Published: May 1, 2025

Language: Английский

Citations

0
Osmotic Pressure Induced Morphological Transformation of Membranized Coacervates DOI
Xin Qiao, Xiaoliang Wang, Haixu Chen

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: May 9, 2025

The stimulus-response behavior of protocells under environmental osmotic pressure changes has long been a subject scientific inquiry. Herein, we demonstrate way to membranized coacervate microdroplets based on cholesterol anchoring phospholipids, which provides enhanced stability, enabling morphological transformations instead dissociation during subsequent changes. In hypotonic environments, these coacervates equilibrate through transient internal vacuole formation, concomitant with transmembrane substrate influx that triggers enzymatic reaction acceleration. By contrast, in hypertonic environment, the responds bursting-like deformation can then quickly recover due effect phospholipids. Notably, it is found such could even successfully induce endocytosis Staphylococcus aureus by coacervates. Furthermore, integration Coa@DMPC's responsiveness, actin polymerization activated endocytic S. achieved. Not only our proposed method phospholipid membranization contribute new model mimic more complex bionic structures, but also revealed response various expected help explain stress behaviors and emerging unique properties cells similar environments.

Language: Английский

Citations

0
Interactions of Clay Minerals with Biomolecules and Protocells Complex Structures in the Origin of Life: A Review DOI
Ying Yan, Huaming Yang

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 21, 2024

Abstract The origin of life (OoL) has always been a mysterious and challenging topic that puzzles human beings. Clay minerals have unique properties wide distribution in early Earth environments. They can not only adsorb biological small molecules to catalyze their polymerization, but play an active role the formation evolution protocells. In this review, research progress on interactions clay with biomolecules protocells complex structures field OoL based chemical theory is summarized. types, minerals, protocell models related are introduced detail. mechanism interaction between molecules, construction formation, structure stability systematically described. Finally, future priorities challenges discussed. It aspired review further advance exploration from new perspective, also bring some interesting findings ideas interdisciplinary materials, biology, chemistry other disciplines.Clay variety biomolecules, which be used as structural functional templates promote organic synthesis protocells, playing non‐negligible OoL.

Language: Английский

Citations

2