Design of metal ion-catecholate complexes towards advanced materials
Yuan Zou,
No information about this author
Xianheng Wang,
No information about this author
Yiwen Li
No information about this author
et al.
Materials Today,
Journal Year:
2024,
Volume and Issue:
79, P. 112 - 133
Published: Aug. 8, 2024
Language: Английский
Construction of natural hydrogels consisting of oxidized dextran, quaternized chitosan and cuttlefish ink nanoparticles for treating diabetic oral ulcers
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
283, P. 137737 - 137737
Published: Nov. 17, 2024
Language: Английский
Bio‐Inspired Self‐Renewing Implant Surfaces With Sequential Biofunctional Adaptation for Infectious Diabetic Tissue Repair
Bin Cui,
No information about this author
Min Wen,
No information about this author
Zhe Cai
No information about this author
et al.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
Abstract
The
clinical
success
of
bioinert,
tissue‐interfacing
metallic
implants
is
greatly
jeopardized
by
complications
such
as
infections,
inflammation,
and
poor
regeneration
or
biointegration,
especially
concerning
diabetics.
Implants
featuring
self‐renewable
surfaces
that
sequentially
dictate
antibacterial/anti‐inflammatory,
immunomodulatory,
pro‐healing/‐regenerative
functionalities
represent
an
emerging
solution.
Herein,
fusing
triple
marine
bioinspirations,
namely
the
multilayered
interlocked
interfaces
mollusk
shells,
adhesive/reactive
chemistries
mussels,
self‐renewing,
release‐active
mucus
layers
corals,
a
self‐adaptive
interfacial
engineering
strategy
imparts
self‐renovating
temporally‐activatable
biofunctionalities
to
various
inert
biometallic
devices
presented.
Specifically,
sandwich‐like
coatings
are
in
situ
constructed,
comprising
substrate‐derived
micro/nanostructured
prelayer,
mussel‐inspired
bioadhesive
interlayer,
polyphenol–antibiotic
dynamically‐crosslinked
therapeutic
gel
toplayer.
dynamic
bonds
within
allowed
pH/reactive
oxygen
species‐responsive
surface
degradation,
localized
release
multifunctional
therapeutics,
conditional
exposure
cell‐supportive
chemical
moieties
micro/nanotopographies.
Systematic
in‐vitro,
in‐ovo,
in‐vivo
(spanning
osseous,
subcutaneous,
wound‐closure
implantations)
studies
demonstrated
functionalized
bone
wound
closure
staples
possessed
adaptive
biocompatibility
(cyto‐/hemo/‐tissue‐compatibility)
combat
device‐associated
infections
spur
diabetic
tissue
repair.
This
study
underscores
potential
coating
strategies
for
orchestrating
complex
(even
contradictory)
biological
functions
addressing
challenging
medical
conditions
require
implant
intervention.
Language: Английский
A greener prescription: the power of natural organic materials in healthcare
RSC Sustainability,
Journal Year:
2024,
Volume and Issue:
2(8), P. 2190 - 2198
Published: Jan. 1, 2024
Natural
organic
materials
might
offer
a
sustainable
solution
at
the
crossroads
of
technological
progress
and
environmental
degradation.
Language: Английский
Unearthing the Potential Therapeutic Effects of Oxyresveratrol Based on Intrinsic Links between Pharmacological Effects: Implications for the Gut–Liver–Brain Axis
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(8), P. 1063 - 1063
Published: Aug. 13, 2024
Oxyresveratrol
is
a
stilbene
compound
with
simple
chemical
structure
and
various
therapeutic
potentials.
This
study
summarized
analyzed
the
multiple
pharmacological
effects
mechanisms
of
oxyresveratrol,
identifying
its
prominent
performance
in
neuroprotection,
hepatoprotection,
anti-inflammatory
activities
intestines.
By
integrating
oxyresveratrol
insights
from
network
pharmacology
molecular
docking
interactions
targets
linked
to
gut-liver-brain
axis
disorders,
it
has
been
shown
that
may
hold
promise
for
treatment
axis-related
disorders.
The
synergistic
effect
between
inspired
further
research
development
oxyresveratrol's
application
value.
Language: Английский
Disclosing novel melanogenesis pathways: Formation of unexpected biphenyl-type dimers through radical–radical coupling by solid-state oxidation of the melanin biosynthetic precursor 5,6-dihydroxyindole
Bioorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
153, P. 107928 - 107928
Published: Oct. 30, 2024
Language: Английский