Nanocarriers for intracellular delivery of molecular payload triggered by visible light DOI Creative Commons

Ashutosh Kanojiya,

Julian Terglane,

Volker Gerke

et al.

Soft Matter, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

Stimuli-responsive nanocontainers have emerged as promising vehicles to deliver molecular payloads into the cytosol of cells in a spatially, temporally and dosage-controlled manner. These respond specific type stimulus such change redox status, enzymatic activity, pH, heat, light, others. In this work, we introduce photoresponsive based on self-assembly vesicles with surface-confined cyclodextrin-adamantane host-guest chemistry. The nanocontainer surface is protected by polymer shell tetrazine cross-linker that enables triggered delivery upon exposure green light (515 nm). We show release vesicle-encapsulated payload achieved also visible which less harmful than UV-light responsive reported previously for

Language: Английский

Stimuli-responsive polymers at the interface with biology DOI Creative Commons
Nathan R. B. Boase, Elizabeth R. Gillies, Rubayn Goh

et al.

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

Inspired by the responsiveness of natural systems to their surrounding environments, researchers have sought understand these biological processes and develop functional stimuli-responsive polymeric for a wide range applications such as drug delivery, imaging, regenerative medicine. Both synthetic polymers biopolymers been studied incorporated into assemblies different morphologies well hydrogels with diverse shapes dimensions. This special issue highlights recent research advances in this area, exciting challenges be tackled upcoming years.

Language: Английский

Citations

0
Functional stimuli-responsive polymers on micro- and nano-patterned interfaces DOI
Jin Ge, Eugene B. Caldona,

Rigoberto C. Advincula

et al.

Polymer, Journal Year: 2024, Volume and Issue: 317, P. 127958 - 127958

Published: Dec. 15, 2024

Language: Английский

Citations

1
Probing the inner structure and dynamics of pH-sensitive block copolymer nanoparticles with nitroxide radicals using scattering and EPR techniques DOI
Svetlana Lukáš Petrova, Alessandro Jäger,

Ewa Pavlova

et al.

European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113473 - 113473

Published: Sept. 1, 2024

Language: Английский

Citations

0
Nanocarriers for intracellular delivery of molecular payload triggered by visible light DOI Creative Commons

Ashutosh Kanojiya,

Julian Terglane,

Volker Gerke

et al.

Soft Matter, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

Stimuli-responsive nanocontainers have emerged as promising vehicles to deliver molecular payloads into the cytosol of cells in a spatially, temporally and dosage-controlled manner. These respond specific type stimulus such change redox status, enzymatic activity, pH, heat, light, others. In this work, we introduce photoresponsive based on self-assembly vesicles with surface-confined cyclodextrin-adamantane host-guest chemistry. The nanocontainer surface is protected by polymer shell tetrazine cross-linker that enables triggered delivery upon exposure green light (515 nm). We show release vesicle-encapsulated payload achieved also visible which less harmful than UV-light responsive reported previously for

Language: Английский

Citations

0