Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107031 - 107031
Published: May 1, 2025
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107031 - 107031
Published: May 1, 2025
Language: Английский
Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(3)
Published: March 1, 2025
ABSTRACT This work presents the synthesis of a polymeric nanosystem from poly(ethylene glycol) methyl ether methacrylate (PEGMEMA) brushes anchored on polydopamine nanoparticles (PDA@PEGMEMA) via surface‐initiated ARGET ATRP technique. The PDA nanoparticle was prepared by polymerizing dopamine in an aqueous buffer solution tris(hydroxymethyl)methylamine. Then, surface modified lysine to form effective group surface, which can be easily with polymers for drug delivery application. Besides that, behavior anticancer doxorubicin (DOX) uptake/release loaded system PDA@PEGMEMA, showed conjugation efficiency 52%, and its effect cancer cells have been investigated. successful confirmed SEM, size distribution 300–400 nm. Poly(ethylene successfully conjugated PDA, investigated FTIR, DLS, XPS. In vitro studies, exhibit excellent biocompatibility, controlled release, enhanced DOX therapeutic efficacy (caco‐2) cell lines, makes them promising candidates as treatment.
Language: Английский
Citations
0Bioorganic & Medicinal Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown, P. 130211 - 130211
Published: March 1, 2025
Language: Английский
Citations
0ACS Applied Electronic Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 3, 2025
Language: Английский
Citations
0Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107031 - 107031
Published: May 1, 2025
Language: Английский
Citations
0