Nanotechnology in Glioblastoma Therapy: Advances in Drug Delivery Systems and Diagnostic Approaches DOI Creative Commons

Maimoona Qindeel,

Mahnoor Irfan,

Sami Ullah

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 102, P. 106322 - 106322

Published: Oct. 24, 2024

Language: Английский

Advanced Nanoparticle Engineering for Precision Therapeutics of Brain Diseases DOI
Muhammad Ismail, Jiayi Liu,

Ningyang Wang

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: 318, P. 123138 - 123138

Published: Jan. 28, 2025

Language: Английский

Citations

1

AI-Driven Innovations in Smart Multifunctional Nanocarriers for Drug and Gene Delivery: A Mini-Review DOI

H. Noury,

Abbas Rahdar, Luiz Fernando Romanholo Ferreira

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104701 - 104701

Published: March 1, 2025

Language: Английский

Citations

1

Application of Multifunctional Metal Nanoparticles in the Treatment of Glioma DOI Creative Commons
Yanhong Ren, Han Yang, Duo Xu

et al.

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 625 - 638

Published: Jan. 1, 2025

Glioma is the most common primary malignant brain tumor with a poor survival rate.It characterized by diffuse and invasive growth heterogeneity, which limits identification complete resection.Therefore, precise detection postoperative adjuvant therapy of gliomas have become increasingly important urgent.Nanotechnology, its excellent biocompatibility controllable chemical properties, has attracted much attention in recent decades.Metal nanoparticles are widely used field biomedical imaging detection, shown promising applications targeted drug delivery therapy.The current review aims to systematically summarize application different types metal treatment glioma.We also discussed advantages mechanisms when for glioma therapy, including chemotherapy, radiotherapy photothermal therapy.We hope promote metallic diagnosis treatment, moving towards clinical translation benefit patients.

Language: Английский

Citations

0

Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications DOI Open Access
Farangis Shahi,

Sara Zarei,

Razhan Salah Othman

et al.

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 1, 2025

ABSTRACT Recent developments in polymer materials have led to an increased implementation of hydrogels biomedical settings, especially the creation smart hydrogels. Traditional single‐network often exhibit challenges, such as poor mechanical strength, insufficient biocompatibility, and slow response rates. To address these issues, researchers introduced Interpenetrating Polymer Network (IPN) hydrogels, which significantly improve strength via topological entanglements physical interactions. This dual‐network design not only enhances biocompatibility but also responsiveness stimuli, endowing with distinctive properties like cell adhesion, conductivity, hemostatic functions, antioxidant abilities, color‐changing properties. The purpose this article is elucidate factors that trigger stimuli IPN their impacts on cellular behavior, various applications they can serve. A comprehensive overview provided regarding classification, mechanisms, performance attributes, related subjects. Ultimately, review emphasizes promise hold fulfilling increasing need for innovative improved features sector.

Language: Английский

Citations

0

Stimuli-responsive polymers at the interface with biology DOI Creative Commons
Nathan R. B. Boase, Elizabeth R. Gillies, Rubayn Goh

et al.

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

Inspired by the responsiveness of natural systems to their surrounding environments, researchers have sought understand these biological processes and develop functional stimuli-responsive polymeric for a wide range applications such as drug delivery, imaging, regenerative medicine. Both synthetic polymers biopolymers been studied incorporated into assemblies different morphologies well hydrogels with diverse shapes dimensions. This special issue highlights recent research advances in this area, exciting challenges be tackled upcoming years.

Language: Английский

Citations

0

Enhanced Vitamin D3 Adsorption Through Novel Hydrophobic Halloysite–Alginate Biopolymer Composites DOI Open Access
Mervenur Kirazoğlu, B. Gönül

Polymers, Journal Year: 2025, Volume and Issue: 17(8), P. 1083 - 1083

Published: April 17, 2025

This study presents a sustainable strategy to enhance polymer encapsulation, adsorption, and functional properties by chemically modifying sodium alginate with hydrophobic groups. Hydrophobic derivatives were synthesized via solvent-free method using hexadecyl trimethylammonium bromide, resulting in nanoparticles capable of effectively capturing non-polar compounds. To further improve compatibility within alginate-based biocomposites, halloysite nanotubes modified through ball milling surfactant-assisted treatments. The nanocomposites (MBHA MHHA) exhibited significantly enhanced adsorption controlled release behavior, as confirmed FTIR analysis ester conjugation. Vitamin D3 followed the Langmuir isotherm, high correlation coefficients (R2 = 0.998 for MBHA R2 0.991 MHHA), indicating monolayer on homogenous surface. Kinetic modeling revealed that process adhered pseudo-second-order model 0.9969 0.999 suggesting chemisorption was dominant rate-controlling mechanism. These results demonstrate critical role surface modification designing nano-engineered biopolymers superior stability, profiles, offering applications medicine, agriculture, environmental remediation.

Language: Английский

Citations

0

Stimuli-Responsive Peptide/siRNA Nanoparticles as a Radiation Sensitizer for Glioblastoma Treatment by Co-Inhibiting RELA/P65 and EGFR DOI Creative Commons
Bohong Cen, Jiän Zhang, Xinghua Pan

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 11517 - 11537

Published: Nov. 1, 2024

To develop a novel approach for increasing radiosensitivity in glioblastoma (GBM) by using targeted nanoparticles to deliver siRNA aimed at silencing the EGFR and RELA/P65 genes, which are implicated radioresistance.

Language: Английский

Citations

3

Nanotechnology in Glioblastoma Therapy: Advances in Drug Delivery Systems and Diagnostic Approaches DOI Creative Commons

Maimoona Qindeel,

Mahnoor Irfan,

Sami Ullah

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 102, P. 106322 - 106322

Published: Oct. 24, 2024

Language: Английский

Citations

1