Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(41), P. 22720 - 22727
Published: Oct. 4, 2023
Construction
of
gold-based
metal-organic
frameworks
(Au-MOFs)
would
bring
the
merits
gold
chemistry
into
MOFs.
However,
it
still
remains
challenging
because
cations
are
easily
reduced
to
metallic
under
solvothermal
conditions.
Herein,
we
present
first
example
Au-MOFs
prepared
from
networking
cyclic
trinuclear
gold(I)
complexes
by
formal
transimination
reaction
in
a
rapid
(<15
min)
and
scalable
(up
1
g)
fashion
ambient
condition.
The
feature
uniform
porosity,
high
crystallinity,
superior
chemical
stability
toward
base
(i.e.,
20
M
NaOH).
With
open
Au(I)
sites
skeleton,
as
heterogeneous
catalysts
delivered
good
performance
substrate
tolerance
for
carboxylation
reactions
alkynes
with
CO2.
This
work
demonstrates
facile
approach
reticularly
synthesize
combining
coordination
dynamic
covalent
chemistry.
Chemical Reviews,
Journal Year:
2021,
Volume and Issue:
122(2), P. 1543 - 1625
Published: Oct. 8, 2021
In
recent
years,
visible
light-induced
transition
metal
catalysis
has
emerged
as
a
new
paradigm
in
organic
photocatalysis,
which
led
to
the
discovery
of
unprecedented
transformations
well
improvement
known
reactions.
this
subfield
complex
serves
double
duty
by
harvesting
photon
energy
and
then
enabling
bond
forming/breaking
events
mostly
via
single
catalytic
cycle,
thus
contrasting
established
dual
photocatalysis
an
exogenous
photosensitizer
is
employed.
addition,
approach
often
synergistically
combines
catalyst–substrate
interaction
with
photoinduced
process,
feature
that
uncommon
conventional
photoredox
chemistry.
This
Review
describes
early
development
advances
emerging
field.
Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
123(8), P. 4237 - 4352
Published: Jan. 24, 2023
The
emergence
of
modern
photocatalysis,
characterized
by
mildness
and
selectivity,
has
significantly
spurred
innovative
late-stage
C–H
functionalization
approaches
that
make
use
low
energy
photons
as
a
controllable
source.
Compared
to
traditional
strategies,
photocatalysis
paves
the
way
toward
complementary
and/or
previously
unattainable
regio-
chemoselectivities.
Merging
compelling
benefits
with
workflow
offers
potentially
unmatched
arsenal
tackle
drug
development
campaigns
beyond.
This
Review
highlights
photocatalytic
strategies
small-molecule
drugs,
agrochemicals,
natural
products,
classified
according
targeted
bond
newly
formed
one.
Emphasis
is
devoted
identifying,
describing,
comparing
main
mechanistic
scenarios.
draws
critical
comparison
between
established
ionic
chemistry
photocatalyzed
radical-based
manifolds.
aims
establish
current
state-of-the-art
illustrate
key
unsolved
challenges
be
addressed
in
future.
authors
aim
introduce
general
readership
functionalization,
specialist
practitioners
evaluation
methodologies,
potential
for
improvement,
future
uncharted
directions.
Chemical Reviews,
Journal Year:
2021,
Volume and Issue:
121(14), P. 8478 - 8558
Published: Feb. 8, 2021
The
catalyst-directed
divergent
synthesis,
commonly
termed
as
"divergent
catalysis",
has
emerged
a
promising
technique
it
allows
chartering
of
structurally
distinct
products
from
common
substrates
simply
by
modulating
the
catalyst
system.
In
this
regard,
gold
complexes
powerful
catalysts
they
offer
unique
reactivity
profiles
compared
to
various
other
transition
metal
catalysts,
primarily
due
their
salient
electronic
and
geometrical
features.
Owing
tunable
soft
π-acidic
nature,
not
only
evolved
superior
contenders
for
catalyzing
reactions
alkynes,
alkenes,
allenes
but
also,
more
intriguingly,
have
been
found
provide
reaction
pathways
over
π-acid
such
Ag,
Pt,
Pd,
Rh,
Cu,
In,
Sc,
Hg,
Zn,
etc.
recent
past
witnessed
renaissance
in
examples
wherein,
choosing
or
fine-tuning
ligands,
counteranions
oxidation
states
itself,
complete
switch
was
observed.
However,
reviews
documenting
are
sporadic;
result,
most
reports
kind
remained
scattered
literature,
thereby
hampering
further
development
burgeoning
field.
By
conceptualizing
idea
"Divergent
Gold
Catalysis
(DGC)",
review
aims
consolidate
all
unified
approach
necessary
pave
way
advancement
exciting
area.
Based
on
factors
governing
divergence
product
formation,
an
explicit
classification
DGC
provided.
To
gain
fundamental
understanding
observed
reactivities
selectivities,
is
accompanied
mechanistic
insights
at
appropriate
places.
Chemical Society Reviews,
Journal Year:
2021,
Volume and Issue:
50(18), P. 10422 - 10450
Published: Jan. 1, 2021
This
review
highlights
a
decade-long
journey
of
Au-catalyzed
1,2-difunctionalization
reactions
C–C
multiple
bonds
that
have
been
realized
due
to
the
productive
integration
Au(
i
)/Au(
iii
)catalysis
with
unique
π-activation
mode
gold
complexes.
Journal of the American Chemical Society,
Journal Year:
2022,
Volume and Issue:
144(16), P. 7089 - 7095
Published: April 18, 2022
Presented
herein
is
the
first
report
of
enantioselective
Au(I)/Au(III)
redox
catalysis,
enabled
by
a
newly
designed
hemilabile
chiral
(P,N)-ligand
(ChetPhos).
The
potential
this
concept
has
been
demonstrated
development
1,2-oxyarylation
and
1,2-aminoarylation
alkenes
which
provided
direct
access
to
medicinally
relevant
3-oxy-
3-aminochromans
(up
88%
yield
99%
ee).
DFT
studies
were
carried
out
unravel
enantiodetermining
step,
revealed
that
stronger
trans
influence
phosphorus
allows
selective
positioning
substrate
in
C2-symmetric
environment
present
around
nitrogen,
imparting
high
level
enantioselectivity.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(16), P. 8810 - 8816
Published: April 16, 2023
Herein,
we
report
a
gold-catalyzed
Heck
reaction
facilitated
by
the
ligand-enabled
Au(I)/Au(III)
redox
catalysis.
The
elementary
organometallic
steps
such
as
migratory
insertion
and
β-hydride
elimination
have
been
realized
in
catalytic
fashion
for
first
time
gold
chemistry.
present
methodology
not
only
overcomes
limitations
of
previously
known
transition
metal-catalyzed
reactions
requirement
specialized
substrates
formation
mixture
regioisomeric
products
result
undesirable
chain-walking
process
but
also
offers
complementary
regioselectivity
compared
to
other
metal
