Enzyme-Immobilized Porous Crystals for Environmental Applications DOI
Hao Wang,

Xiaoxue Kou,

Rui Gao

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(27), P. 11869 - 11886

Published: June 28, 2024

Developing efficient technologies to eliminate or degrade contaminants is paramount for environmental protection. Biocatalytic decontamination offers distinct advantages in terms of selectivity and efficiency; however, it still remains challenging when applied complex matrices. The main challenge originates from the instability difficult-to-separate attributes fragile enzymes, which also results issues compromised activity, poor reusability, low cost-effectiveness, etc. One viable solution harness biocatalysis environments known as enzyme immobilization, where a flexible tightly fixed solid carrier. In case reticular crystal utilized support, feasible engineer next-generation biohybrid catalysts functional complicated media. This can be interpreted by three aspects: (1) highly crystalline skeleton shield immobilized against external stressors. (2) porous network ensures high accessibility interior catalytic decontamination. And (3) adjustable unambiguous structure framework favors in-depth understanding interfacial interaction between enzyme, turn guide us designing active biocomposites. Review aims introduce this emerging technology involving pollutant degradation greenhouse gas (carbon dioxide) conversion, with emphasis on immobilization protocols diverse catalysis principles including single catalysis, cascades, photoenzyme-coupled catalysis. Additionally, remaining challenges forward-looking directions field are discussed. We believe that may offer useful biocatalytic contribute green sustainable manner will inspire more researchers at intersection environment science, biochemistry, materials science communities co-solve problems.

Language: Английский

Opportunities of CO2-based biorefineries for production of fuels and chemicals DOI Creative Commons
Zihe Liu, Shuobo Shi,

Yuchao Ji

et al.

Green Carbon, Journal Year: 2023, Volume and Issue: 1(1), P. 75 - 84

Published: Sept. 1, 2023

Biorefinery production of fuels and chemicals represents an attractive route for solving current energy crisis, as well reducing green-house gas (GHG) emissions from ships, planes, long-haul trucks. The biorefinery industry is under transition the use food (1 G, 1st generation), to biomass (2 2nd generation). Moreover, atmospheric CO2 (3 3rd generation) has caught increased attention possible next-generation biorefinery. Here we discuss how microorganisms can be engineered CO2-based biorefineries produce chemicals. We start through reviewing different metabolic pathways that recruited fixation, followed by opportunities either co-consumption with sugars or used sole carbon source. Key challenges future research directions advancing 3rd-generation are also discussed.

Language: Английский

Citations

53
Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems DOI Creative Commons
Souvik Ghosh, Mathieu G. Baltussen, Nikita M. Ivanov

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2553 - 2582

Published: March 4, 2024

The intricate and complex features of enzymatic reaction networks (ERNs) play a key role in the emergence sustenance life. Constructing such vitro enables stepwise build up complexity introduces opportunity to control activity using physicochemical stimuli. Rational design modulation network motifs enable engineering artificial systems with emergent functionalities. Such functional are useful for variety reasons as creating new-to-nature dynamic materials, producing value-added chemicals, constructing metabolic modules synthetic cells, even enabling molecular computation. In this review, we offer insights into chemical characteristics ERNs while also delving their potential applications associated challenges.

Language: Английский

Citations

26
Photocatalytic CO2 Reduction Using CO2‐Binding Enzymes DOI Creative Commons
Henrik Terholsen, H Huerta-Zerón, Christina Möller

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(16)

Published: Feb. 7, 2024

Abstract Novel concepts to utilize carbon dioxide are required reach a circular economy and minimize environmental issues. To achieve these goals, photo‐, electro‐, thermal‐, biocatalysis key tools realize this, preferentially in aqueous solutions. Nevertheless, catalytic systems that operate efficiently water scarce. Here, we present general strategy for the identification of enzymes suitable CO 2 reduction based on structural analysis potential binding sites subsequent mutations. We discovered phenolic acid decarboxylase from Bacillus subtilis (BsPAD) promotes photocatalytic selectively monoxide presence ruthenium photosensitizer sodium ascorbate. With engineered variants BsPAD, TONs up 978 selectivities 93 % (favoring desired over H generation) were achieved. Mutating active site region BsPAD further improved turnover numbers generation. This also revealed electron transfer is rate‐limiting occurs via multistep tunneling. The generality this approach was proven by using eight other enzymes, all showing activity underlining range proteins capable reduction.

Language: Английский

Citations

22
Molecular modulation of nickel–salophen organic frameworks enables the selective photoreduction of CO2 at varying concentrations DOI
Xiaohan Yu, Mingzi Sun,

Tianran Yan

et al.

Energy & Environmental Science, Journal Year: 2024, Volume and Issue: 17(6), P. 2260 - 2268

Published: Jan. 1, 2024

Metal–salophen organic frameworks with dispersed metal centers and precise coordination environments were synthesized. The optimal sample exhibited great photocatalytic activity near-unity CO selectivity over a wide range of 2 concentrations.

Language: Английский

Citations

19
Engineering carbon assimilation in plants DOI Open Access
Kezhen Qin,

Xingyan Ye,

Shanshan Luo

et al.

Journal of Integrative Plant Biology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

Abstract Carbon assimilation is a crucial part of the photosynthetic process, wherein inorganic carbon, typically in form CO 2 , converted into organic compounds by living organisms, including plants, algae, and subset bacteria. Although several carbon fixation pathways have been elucidated, Calvin–Benson–Bassham (CBB) cycle remains fundamental to metabolism, playing pivotal role biosynthesis starch sucrose cyanobacteria. However, Ribulose‐1,5‐bisphosphate carboxylase/oxygenase (RuBisCO), key carboxylase enzyme CBB cycle, exhibits low kinetic efficiency, substrate specificity, high temperature sensitivity, all which potential limit flux through this pathway. Consequently, RuBisCO needs be present at very concentrations, one factors contributing its status as most prevalent protein on Earth. Numerous attempts made optimize catalytic efficiency thereby promote plant growth. Furthermore, limitations process highlight benefits engineering or discovering more efficient mechanisms, either improving itself introducing alternative pathways. Here, we review advances artificial engineering, integration synthetic biology, genetic metabolic pathway optimization, intelligence order create plants capable performing photosynthesis. We additionally provide perspective current challenges solutions alongside personal opinion promising future directions emerging field.

Language: Английский

Citations

3
From green to circular chemistry paved by biocatalysis DOI Creative Commons
Pedro Lozano, Eduardo Garcı́a-Verdugo

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(18), P. 7041 - 7057

Published: Jan. 1, 2023

Biocatalysts raised by the green chemistry and circular principles can constitute most important efficient strategy for achieving many of 17 Sustainable Development Goals launched UN.

Language: Английский

Citations

29
Synergistic effects of core–shell poly(ionic liquids)@ZIF-8 nanocomposites for enhancing additive-free CO2 conversion DOI

Jiqing Dong,

Han Zhang, Jingjing Ma

et al.

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 661, P. 1000 - 1010

Published: Feb. 6, 2024

Language: Английский

Citations

17
Assessing various CO2 utilization technologies: a brief comparative review DOI
Zafar Turakulov, Azizbek Kamolov, Adham Norkobilov

et al.

Journal of Chemical Technology & Biotechnology, Journal Year: 2024, Volume and Issue: 99(6), P. 1291 - 1307

Published: Jan. 31, 2024

Abstract Carbon dioxide (CO 2 ) utilization technologies have emerged as a promising approach to address the direct and indirect consequences of climate change need for sustainable resource management. Those innovative aim capture utilize CO by converting it into valuable products or directly using chemical feedstock in various industries, thus, avoiding their release atmosphere. In this study, different pathways including chemicals fuels, building materials, enhanced oil recovery (EOR), bio‐products are discussed terms status – economic, environmental technology readiness level performances. Moreover, comparatively analyzed considering advantages drawbacks, uptake potentials, overall benefits. According comparison results, photocatalytic electrochemical reduction along with bio‐fixation gaining more attention recent research investigations, from energy intensity point view, whereas EOR remains dominant scalability, maturity economic However, limitations related capacity, life cycle geolocations, well complexities other mature approaches make room emerging be energy‐effective environmentally friendly. Overall, most techniques either technologically immature limited scale deploy globally. One main barriers reusing is associated high cost ‐based production low value market. © 2024 Society Chemical Industry (SCI).

Language: Английский

Citations

16
Application of Immobilized Enzymes in Flow Biocatalysis for Efficient Synthesis DOI
Zhongyao Tang, Yuri Oku, Tomoko Matsuda

et al.

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: 28(5), P. 1308 - 1326

Published: March 8, 2024

Flow chemistry as well biocatalysis contribute to achieve green industries and sustainable development. Now there is an approach that combines them, called flow biocatalysis, which attracts more attention. In enzyme immobilization plays a powerful role in promoting its This review begins with general introduction of then provides update on the application immobilized enzymes biocatalysis. Oxidation–reduction, hydrolysis–esterification, transferase reaction, condensation, carboxylation, multistep cascade reactions continuous-flow process are discussed detail.

Language: Английский

Citations

16
Atomically Dispersed Metal Catalysts for the Conversion of CO2 into High‐Value C2+ Chemicals DOI
Qihao Yang,

Hao Liu,

Yichao Lin

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(37)

Published: May 19, 2024

Abstract The conversion of carbon dioxide (CO 2 ) into value‐added chemicals with two or more carbons (C 2+ is a promising strategy that cannot only mitigate anthropogenic CO emissions but also reduce the excessive dependence on fossil feedstocks. In recent years, atomically dispersed metal catalysts (ADCs), including single‐atom (SACs), dual‐atom (DACs), and single‐cluster (SCCs), emerged as attractive candidates for fixation reactions due to their unique properties, such maximum utilization active sites, tunable electronic structure, efficient elucidation catalytic mechanism, etc. This review provides an overview significant progress in synthesis characterization ADCs utilized photocatalytic, electrocatalytic, thermocatalytic toward high‐value C compounds. To provide insights designing chemical originating from , key factors influence activity selectivity are highlighted. Finally, relevant challenges opportunities discussed inspire new ideas generation ‐based products over ADCs.

Language: Английский

Citations

13