Journal of Materials Chemistry A, Journal Year: 2024, Volume and Issue: 12(27), P. 16457 - 16465
Published: Jan. 1, 2024
An eye-wearable Ti 3 C 2 T x MXene-based micro-supercapacitor was fabricated on a soft hemispherical substrate, which can be used as an efficient power unit for intraocular pressure applications.
Language: Английский
Advanced Materials, Journal Year: 2024, Volume and Issue: 36(35)
Published: June 19, 2024
Abstract Despite of the substantial potential human‐derived retinal organoids, degeneration ganglion cells (RGCs) during maturation limits their utility in assessing functionality later‐born cell subtypes. Additionally, conventional analyses primarily rely on fluorescent emissions, which detection actual while risking damage to 3D cytoarchitecture organoids. Here, an electrophysiological analysis is presented monitor RGC development early mid‐stage and compare distinct features with fully‐mature mouse retina. This approach utilizes high‐resolution printing liquid‐metal microelectrodes, enabling precise targeting specific inner layers within The adaptable distribution softness these microelectrodes facilitate spatiotemporal recording signals. study not only demonstrates functional properties RGCs organoid but also provides insights into synaptic connectivity, reminiscent fetal native retinas. Further comparison retina vivo verifies features, highlighting early‐stage organoids biomedical research.
Language: Английский
Citations
6
Advanced Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 11, 2024
Abstract The low electrical conductivity of conductive hydrogels limits their applications as soft conductors in bioelectronics. This originates from the high water content hydrogels, which impedes facile carrier transport between fillers. study presents a highly and stretchable hydrogel nanocomposite comprising whiskered gold nanosheets. A dry network nanosheets is fabricated then incorporated into wet matrices. preserve tight interconnection despite content, providing high‐quality percolation even under stretched states. Regardless type matrix, gold‐hydrogel nanocomposites exhibit ≈520 S cm −1 stretchability ≈300% without requiring dehydration process. reaches maximum ≈3304 when density controlled. gold‐adhesive nanocomposite, can achieve conformal adhesion to moving organ surfaces, for bioelectronics demonstrations. adhesive electrode outperforms elastomer‐based electrodes vivo epicardial electrogram recording, pacing, sciatic nerve stimulation.
Language: Английский
Citations
5
Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 379, P. 920 - 926
Published: Jan. 31, 2025
Language: Английский
Citations
0
Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)
Published: Nov. 2, 2023
Abstract Despite the existence of numerous eye drops in market, most them are not sufficiently effective because quick clearance and barriers within eye. To increase delivery drugs to eye, various new formulations have been explored recent decades. These aim enhance drug retention penetration, while enabling sustained release over extended periods. One such innovative approach is utilization contact lenses, which were originally designed for cosmetic purposes vision correction. Contact lenses appeared as a promising formulation ocular delivery, they can bioavailability diminish unwanted side effects. They specifically appropriate treating chronic conditions, making an area interest researchers field ophthalmology. This review outlines potential nanomaterial-laden diagnosis treatment glaucoma. It classifies therapeutic approaches based on nanomaterial type, summarizes diagnostic advances, discusses improvement properties, covers marketing perspectives, acknowledges challenges these glaucoma management.
Language: Английский
Citations
12
Journal of Materials Chemistry A, Journal Year: 2024, Volume and Issue: 12(27), P. 16457 - 16465
Published: Jan. 1, 2024
An eye-wearable Ti 3 C 2 T x MXene-based micro-supercapacitor was fabricated on a soft hemispherical substrate, which can be used as an efficient power unit for intraocular pressure applications.
Language: Английский
Citations
4