Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 20, 2024
Comprehensive
Summary
Deep‐tissue
physiological
signals
are
critical
for
accurate
disease
diagnosis.
Current
clinical
equipment,
however,
often
falls
short
of
enabling
continuous,
long‐term
monitoring.
Wearable
and
implantable
flexible
electronics
offer
a
promising
avenue
addressing
this
limitation,
allowing
in
vivo
signal
collection
paving
the
way
early
diagnosis
personalized
treatment.
A
major
challenge
lies
ensuring
that
these
devices
seamlessly
integrate
with
diverse
microenvironments
throughout
human
body.
Mechanoadaptive
bioelectronics
is
emerging
as
key
solution
to
optimize
acquisition
device
robustness.
This
review
provides
comprehensive
overview
characteristics
various
organs
types
they
generate.
Furthermore,
it
explores
recent
advancements
mechanoadaptive
bioelectronics,
systematically
categorizes
their
strategies,
underscores
potential
revolutionize
healthcare.
Finally,
we
delve
into
ongoing
challenges
field
highlight
directions
advance
adaptability
further.
Key
Scientists
In
2017,
researchers
developed
an
ionic
skin
enhanced
mechanical
compatibility
through
strain‐hardening
properties.
[1]
Three
years
later,
neural
interface
platform
called
adaptive
self‐healing
electronic
epineurium
(A‐SEE)
was
reported.
[2]
minimized
stress
on
tissue
by
dynamically
relaxing
stress.
2021,
hydrogel
hybrid
probe
tracking
isolated
neuroelectric
activity,
optogenetics,
behavioral
studies
circuits.
also
utilized
hydration‐induced
softening
minimize
foreign
body
response.
[3]
same
year,
shape‐adaptive
imager
Kirigami
design
proposed.
[4]
following
morphing
(MorphE)
reported,
which
exhibited
attractive
viscoelasticity
minimal
growing
nerve
during
implantation.
[5]
2023,
standardized
tissue‐electronic
developed,
can
be
implanted
minimally
invasive
cardiac
procedures
rapidly
beating
heart.
[6]
Recently,
needle‐like
microfiber
based
biphasic
liquid
metal
created.
reach
target
site
simply
puncturing
enable
multifunctional
sensing.
[7]
At
about
time,
amalgamated
living
synthetic
components
studying
treating
inflammatory
disease.
[8]
enables
real‐time
digital
updates
potentially
treatment
non‐resolving
inflammation,
enlightening
new
generation
bioelectronics.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 26, 2024
Abstract
The
flexible
pressure
sensors
with
a
broad
range
and
unsaturated
sensitivity
are
highly
desired
in
practical
applications.
However,
by
piezoresistive
effect
always
limited
the
compressibility
of
sensing
layers,
resulting
theoretically
decreasing
less
than
100%.
Here,
unique
strategy
is
proposed
that
utilizes
strain
effect,
simultaneously
achieving
trade‐off
between
wider
detection
sensitivity.
Ascribed
to
layers
induced
interlaced
microdomes,
possess
an
increased
(5.22–70
MPa
−1
)
over
ultrawide
(45
Pa–4.1
MPa),
high‐pressure
resolution
(5
Pa),
fast
response/recovery
time
(30/45
ms),
robust
response
under
loading
3.5
for
more
5000
cycles.
These
superior
performances
allow
sensor
monitor
large
pressure.
array
can
assist
doctors
restoring
neutral
mechanical
axis,
tracking
knee
flexion
angles,
extracting
gait
features.
Moreover,
be
integrated
into
joint
motion
surveillance
system
map
balance
medial–lateral
contact
forces
on
metal
compartments
real
time,
demonstrating
potential
further
development
precise
medical
human–machine
interfaces
during
total
replacement
surgery.
Cyborg and Bionic Systems,
Journal Year:
2024,
Volume and Issue:
5
Published: Jan. 1, 2024
With
the
prevalence
of
cardiovascular
disease,
it
is
imperative
that
medical
monitoring
and
treatment
become
more
instantaneous
comfortable
for
patients.
Recently,
wearable
implantable
optoelectronic
devices
can
be
seamlessly
integrated
into
human
body
to
enable
physiological
in
an
imperceptible
spatiotemporally
unconstrained
manner,
opening
countless
possibilities
intelligent
healthcare
paradigm.
To
achieve
biointegrated
cardiac
healthcare,
researchers
have
focused
on
novel
strategies
construction
flexible/stretchable
systems.
Here,
we
overview
progress
flexible
stretchable
optoelectronics
devices.
Firstly,
device
design
addressed,
including
mechanical
design,
interface
adhesion,
encapsulation
strategies.
Next,
practical
applications
monitoring,
optogenetics,
nongenetic
stimulation
are
presented.
Finally,
outlook
systems
discussed.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(22), P. 12738 - 12843
Published: Nov. 5, 2024
The
quest
to
imbue
machines
with
intelligence
akin
that
of
humans,
through
the
development
adaptable
neuromorphic
devices
and
creation
artificial
neural
systems,
has
long
stood
as
a
pivotal
goal
in
both
scientific
inquiry
industrial
advancement.
Recent
advancements
flexible
electronics
primarily
rely
on
nanomaterials
polymers
owing
their
inherent
uniformity,
superior
mechanical
electrical
capabilities,
versatile
functionalities.
However,
this
field
is
still
its
nascent
stage,
necessitating
continuous
efforts
materials
innovation
device/system
design.
Therefore,
it
imperative
conduct
an
extensive
comprehensive
analysis
summarize
current
progress.
This
review
highlights
applications
neuromorphics,
involving
inorganic
(zero-/one-/two-dimensional,
heterostructure),
carbon-based
such
carbon
nanotubes
(CNTs)
graphene,
polymers.
Additionally,
comparison
summary
structural
compositions,
design
strategies,
key
performance,
significant
these
are
provided.
Furthermore,
challenges
future
directions
pertaining
materials/devices/systems
associated
neuromorphics
also
addressed.
aim
shed
light
rapidly
growing
attract
experts
from
diverse
disciplines
(e.g.,
electronics,
science,
neurobiology),
foster
further
for
accelerated
development.
Nano Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 17, 2025
Strain
sensors
based
on
conductive
elastomers
face
challenges
like
baseline
drift
and
noise
due
to
inherent
viscoelasticity
weak
electrode
interfaces
under
dynamic
strains.
Herein,
a
synergistic
structure
with
biphasic
hierarchical
networks
stable
is
proposed
address
these
issues.
The
sensor
employs
multilayer
polydimethylsiloxane
(PDMS)
substrate,
carbon
nanotube-doped
PDMS
(CNT-PDMS),
Ag
film.
Electrodes
are
fixed
using
rigid
island
reinforced
mortise
tenon
joint
formed
CNT-PDMS.
film
dominates
resistance
during
release,
significantly
reducing
drift.
Strain-insensitive
further
reduce
noise.
This
optimized
design
ensures
99.999%
recovery
without
delay,
even
at
high-speed
(800
mm/min)
large
(80%)
exhibits
high
gauge
factor
of
55442,
low
detection
limit
(0.02%),
excellent
stability
(5000
cycles).
With
the
designed
algorithms,
single-channel
achieves
98.2%
decoding
accuracy
for
various
gestures,
demonstrating
great
potential
wearable
electronics.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(46)
Published: July 18, 2024
Abstract
Ion‐conductive
elastomers
capable
of
damping
can
significantly
mitigate
the
interference
caused
by
mechanical
noise
during
data
acquisition
in
wearable
and
biomedical
devices.
However,
currently
available
often
lack
robust
properties
have
a
narrow
temperature
range
for
effective
damping.
Here,
precise
modulation
weak
to
strong
ion‐dipole
interactions
plays
crucial
role
bolstering
network
stability
tuning
relaxation
behavior
supramolecular
ion‐conductive
(SICEs).
The
SICEs
exhibit
impressive
properties,
including
modulus
13.2
MPa,
toughness
65.6
MJ
m
−3
,
fracture
energy
74.9
kJ
−2
.
Additionally,
they
demonstrate
remarkable
capabilities,
with
capacity
91.2%
peak
tan
δ
1.11.
Furthermore,
entropy‐driven
rearrangement
ensures
SICE
remain
stable
even
at
elevated
temperatures
(18–200
°C,
>
0.3),
making
it
most
thermally
resistant
elastomer
reported
date.
Moreover,
proves
filtering
out
various
noises
physiological
signal
detection
strain
sensing,
highlighting
its
vast
potential
flexible
electronics.
Macromolecular Chemistry and Physics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 18, 2025
Abstract
Functional‐hydrogel‐based
wearable
sensors
are
a
rapidly
evolving
field
in
the
modern
era
due
to
their
various
attractive
features.
Functional
hydrogels
have
great
ability
for
multiple
applications
because
of
unusual
combination
biocompatibility,
flexibility,
and
responsiveness
different
stimuli.
Wearable
electronics
illustrate
next‐generation
technology,
seamlessly
incorporating
sophisticated
features
into
everyday
accessories
provide
continuous
health
monitoring,
real‐time
data
collecting,
improved
human–computer
interactions.
This
review
provides
an
extensive
summary
state
functional
electronics.
The
basic
ideas
behind
first
introduced,
emphasizing
how
they
work
together
harmoniously.
types
synthesis
methods
hydrogels,
including
chemical
physical
cross‐linking
methods,
highlighted.
A
comprehensive
investigation
is
carried
out
intrinsic
properties
conductivity,
mechanical
strength,
stimuli‐responsiveness.
Subsequently,
explored
electronics,
motion
sensors,
electrophysiological
respiratory
gas
body
fluid
biomarker
wound
healing
monitoring.
Recent
developments
valuable
used
show
these
materials
can
revolutionize
design
technology.
researchers
traversing
interdisciplinary
fields
polymer,
bioelectronics,
chemistry.
Interdisciplinary materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 29, 2025
ABSTRACT
To
foster
sustainable
development,
a
pivotal
trend
lies
in
harnessing
energy
supplies
that
propel
modern
economic
and
societal
progress.
Recent
advancements
living
materials
for
applications
have
sparked
groundbreaking
research
area:
engineered
(ELEMs),
which
seamlessly
integrate
biological
artificial
systems
efficient
conversion
storage.
consolidate
this
area,
herein,
we
summarize
delve
into
the
evolution
of
ELEMs.
Firstly,
provide
an
overview
structural
features
mechanisms
employed
by
bio‐modules
spanning
proteins,
organelles,
entire
organisms.
They
can
be
directly
used
as
components
constructing
ELEMs
or
inspirations
design
such
entities.
Then,
comprehensively
review
latest
strides
based
on
their
distinct
modes.
Finally,
discuss
challenges
confronting
envision
future
trajectories.
The
progress
holds
immense
potential
to
catalyze
interdisciplinary
endeavors
encompassing
medicine,
environmental
science,
technologies.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 30, 2025
Abstract
The
ear
harbors
a
wealth
of
critical
physiological
and
pathological
information,
positioning
it
as
an
ideal
site
for
healthcare
monitoring.
However,
the
intricate
geometry
sensitivity
pose
formidable
technical
hurdles
to
effective
Soft
electronics,
renowned
their
mechanical
deformability,
excellent
skin
conformability,
biocompatibility,
offer
compelling
advantages,
particularly
within
emerging
contexts
fifth‐generation
technology
Internet
Things.
These
innovations
provide
essential
support
achieving
comprehensive
monitoring
via
ear‐area
soft
electronics.
This
review
comprehensively
outlines
recent
advancements
in
electronics
advanced
authors
begin
by
elucidating
properties
external,
middle,
inner
from
clinical
perspectives.
Subsequently,
leveraging
these
anatomical
insights,
state‐of‐the‐art
bioelectric,
biophysical,
biochemical,
multimodal
are
explored.
Furthermore,
insights
offered
into
enduring
challenges
prospective
directions
systematic
sensor
design,
data
processing
methodologies,
translational
applications.
As
whole,
will
new
paradigms
shift
evolution
wearable
implantable
thereby
fostering
rapid
high‐quality
development
systems.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 1, 2025
Noncommunicable
diseases
(NCDs)
associated
with
cardiovascular,
neurological,
and
gastrointestinal
disorders
remain
a
leading
cause
of
global
mortality,
sounding
the
alarm
for
urgent
need
better
diagnostic
therapeutic
solutions.
Wearable
implantable
biointegrated
electronics
offer
groundbreaking
solution,
combining
real-time,
high-resolution
monitoring
innovative
treatment
capabilities
tailored
to
specific
organ
functions.
In
this
comprehensive
review,
we
focus
on
affecting
brain,
heart,
organs,
bladder,
adrenal
gland,
along
their
physiological
parameters.
Additionally,
provide
an
overview
characteristics
these
parameters
explore
potential
bioelectronic
devices
in
situ
sensing
applications
highlight
recent
advancements
deployment
across
organs.
Finally,
analyze
current
challenges
prospects
implementing
closed-loop
feedback
control
systems
integrated
sensor-therapy
applications.
By
emphasizing
organ-specific
advocating
systems,
review
highlights
future
bioelectronics
address
needs
serves
as
guide
researchers
navigating
interdisciplinary
fields
diagnostics,
therapeutics,
personalized
medicine.