Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 20, 2024
Comprehensive
Summary
Deep‐tissue
physiological
signals
are
critical
for
accurate
disease
diagnosis.
Current
clinical
equipment,
however,
often
falls
short
of
enabling
continuous,
long‐term
monitoring.
Wearable
and
implantable
flexible
electronics
offer
a
promising
avenue
addressing
this
limitation,
allowing
in
vivo
signal
collection
paving
the
way
early
diagnosis
personalized
treatment.
A
major
challenge
lies
ensuring
that
these
devices
seamlessly
integrate
with
diverse
microenvironments
throughout
human
body.
Mechanoadaptive
bioelectronics
is
emerging
as
key
solution
to
optimize
acquisition
device
robustness.
This
review
provides
comprehensive
overview
characteristics
various
organs
types
they
generate.
Furthermore,
it
explores
recent
advancements
mechanoadaptive
bioelectronics,
systematically
categorizes
their
strategies,
underscores
potential
revolutionize
healthcare.
Finally,
we
delve
into
ongoing
challenges
field
highlight
directions
advance
adaptability
further.
Key
Scientists
In
2017,
researchers
developed
an
ionic
skin
enhanced
mechanical
compatibility
through
strain‐hardening
properties.
[1]
Three
years
later,
neural
interface
platform
called
adaptive
self‐healing
electronic
epineurium
(A‐SEE)
was
reported.
[2]
minimized
stress
on
tissue
by
dynamically
relaxing
stress.
2021,
hydrogel
hybrid
probe
tracking
isolated
neuroelectric
activity,
optogenetics,
behavioral
studies
circuits.
also
utilized
hydration‐induced
softening
minimize
foreign
body
response.
[3]
same
year,
shape‐adaptive
imager
Kirigami
design
proposed.
[4]
following
morphing
(MorphE)
reported,
which
exhibited
attractive
viscoelasticity
minimal
growing
nerve
during
implantation.
[5]
2023,
standardized
tissue‐electronic
developed,
can
be
implanted
minimally
invasive
cardiac
procedures
rapidly
beating
heart.
[6]
Recently,
needle‐like
microfiber
based
biphasic
liquid
metal
created.
reach
target
site
simply
puncturing
enable
multifunctional
sensing.
[7]
At
about
time,
amalgamated
living
synthetic
components
studying
treating
inflammatory
disease.
[8]
enables
real‐time
digital
updates
potentially
treatment
non‐resolving
inflammation,
enlightening
new
generation
bioelectronics.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 30, 2025
Abstract
The
ear
harbors
a
wealth
of
critical
physiological
and
pathological
information,
positioning
it
as
an
ideal
site
for
healthcare
monitoring.
However,
the
intricate
geometry
sensitivity
pose
formidable
technical
hurdles
to
effective
Soft
electronics,
renowned
their
mechanical
deformability,
excellent
skin
conformability,
biocompatibility,
offer
compelling
advantages,
particularly
within
emerging
contexts
fifth‐generation
technology
Internet
Things.
These
innovations
provide
essential
support
achieving
comprehensive
monitoring
via
ear‐area
soft
electronics.
This
review
comprehensively
outlines
recent
advancements
in
electronics
advanced
authors
begin
by
elucidating
properties
external,
middle,
inner
from
clinical
perspectives.
Subsequently,
leveraging
these
anatomical
insights,
state‐of‐the‐art
bioelectric,
biophysical,
biochemical,
multimodal
are
explored.
Furthermore,
insights
offered
into
enduring
challenges
prospective
directions
systematic
sensor
design,
data
processing
methodologies,
translational
applications.
As
whole,
will
new
paradigms
shift
evolution
wearable
implantable
thereby
fostering
rapid
high‐quality
development
systems.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 1, 2025
Noncommunicable
diseases
(NCDs)
associated
with
cardiovascular,
neurological,
and
gastrointestinal
disorders
remain
a
leading
cause
of
global
mortality,
sounding
the
alarm
for
urgent
need
better
diagnostic
therapeutic
solutions.
Wearable
implantable
biointegrated
electronics
offer
groundbreaking
solution,
combining
real-time,
high-resolution
monitoring
innovative
treatment
capabilities
tailored
to
specific
organ
functions.
In
this
comprehensive
review,
we
focus
on
affecting
brain,
heart,
organs,
bladder,
adrenal
gland,
along
their
physiological
parameters.
Additionally,
provide
an
overview
characteristics
these
parameters
explore
potential
bioelectronic
devices
in
situ
sensing
applications
highlight
recent
advancements
deployment
across
organs.
Finally,
analyze
current
challenges
prospects
implementing
closed-loop
feedback
control
systems
integrated
sensor-therapy
applications.
By
emphasizing
organ-specific
advocating
systems,
review
highlights
future
bioelectronics
address
needs
serves
as
guide
researchers
navigating
interdisciplinary
fields
diagnostics,
therapeutics,
personalized
medicine.
Nano Letters,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 12, 2024
Stretchable
supercapacitors
are
essential
components
in
wearable
electronics
due
to
their
low
heat
generation
and
seamless
integration
capabilities.
Thermoplastic
polyurethane
elastomers,
recognized
for
dynamic
hydrogen-bonding
structure,
exhibit
excellent
stretchability,
making
them
well-suited
these
applications.
This
study
introduces
fluorine-based
interactions
the
hard
segments
of
thermoplastic
polyurethanes,
resulting
polyurethanes
with
a
elastic
modulus,
high
fracture
strength,
exceptional
fatigue
resistance,
self-healing
properties.
By
utilizing
as
binders
meshed
fabric
scaffolds,
we
developed
highly
stretchable
conductors.
These
conductors
maintain
resistance
(∼26
ohms)
under
biaxial
stretching
stable
bidirectional
conductivity
after
1600
cycles.
The
fabricated
supercapacitor
electrode,
incorporating
current
collectors,
polyurethane,
MXene,
achieves
an
ultrahigh
areal
specific
capacitance
7200
mF
cm
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 20, 2024
Comprehensive
Summary
Deep‐tissue
physiological
signals
are
critical
for
accurate
disease
diagnosis.
Current
clinical
equipment,
however,
often
falls
short
of
enabling
continuous,
long‐term
monitoring.
Wearable
and
implantable
flexible
electronics
offer
a
promising
avenue
addressing
this
limitation,
allowing
in
vivo
signal
collection
paving
the
way
early
diagnosis
personalized
treatment.
A
major
challenge
lies
ensuring
that
these
devices
seamlessly
integrate
with
diverse
microenvironments
throughout
human
body.
Mechanoadaptive
bioelectronics
is
emerging
as
key
solution
to
optimize
acquisition
device
robustness.
This
review
provides
comprehensive
overview
characteristics
various
organs
types
they
generate.
Furthermore,
it
explores
recent
advancements
mechanoadaptive
bioelectronics,
systematically
categorizes
their
strategies,
underscores
potential
revolutionize
healthcare.
Finally,
we
delve
into
ongoing
challenges
field
highlight
directions
advance
adaptability
further.
Key
Scientists
In
2017,
researchers
developed
an
ionic
skin
enhanced
mechanical
compatibility
through
strain‐hardening
properties.
[1]
Three
years
later,
neural
interface
platform
called
adaptive
self‐healing
electronic
epineurium
(A‐SEE)
was
reported.
[2]
minimized
stress
on
tissue
by
dynamically
relaxing
stress.
2021,
hydrogel
hybrid
probe
tracking
isolated
neuroelectric
activity,
optogenetics,
behavioral
studies
circuits.
also
utilized
hydration‐induced
softening
minimize
foreign
body
response.
[3]
same
year,
shape‐adaptive
imager
Kirigami
design
proposed.
[4]
following
morphing
(MorphE)
reported,
which
exhibited
attractive
viscoelasticity
minimal
growing
nerve
during
implantation.
[5]
2023,
standardized
tissue‐electronic
developed,
can
be
implanted
minimally
invasive
cardiac
procedures
rapidly
beating
heart.
[6]
Recently,
needle‐like
microfiber
based
biphasic
liquid
metal
created.
reach
target
site
simply
puncturing
enable
multifunctional
sensing.
[7]
At
about
time,
amalgamated
living
synthetic
components
studying
treating
inflammatory
disease.
[8]
enables
real‐time
digital
updates
potentially
treatment
non‐resolving
inflammation,
enlightening
new
generation
bioelectronics.
