Biophysical Journal, Journal Year: 2024, Volume and Issue: 123(10), P. 1165 - 1166
Published: April 15, 2024
Language: Английский
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Nov. 8, 2024
The hydration behavior of amino acids, essential for biological macromolecules, is influenced by ammonium biomaterials. protic ionic liquids (PILs) are gaining attention in the food and pharmaceutical industries due to their nontoxicity adjustable properties. Thus, study such as L-proline, presence PILs crucial understanding behavior. In this work, effect PILs, including mono, bis, tris (2-hydroxyethyl)ammonium acetate that might be naturally produced human body, on L-proline was studied using COSMO calculations thermophysical measurements. Measurements were density, speed sound, viscosity, refractive index data solutions (L-proline + water) at various PIL concentrations temperatures (298.15 318.15) K under atmospheric pressure. indicates has weaker interactions with water compared ([2-HEA][Ac], [bis-2-HEA][Ac], [tris-2-HEA][Ac]) its compact structure lower negative dielectric energy. interact more strongly through hydrogen bonding. Increasing temperature affects L-proline's layer, releasing molecules solutions. This pronounced [tris-2-HEA][Ac], likely larger size complex structure. While promotes an ordered structure, can disrupt rearranging forming own bonds.
Language: Английский
Citations
2
Biophysical Reviews and Letters, Journal Year: 2024, Volume and Issue: 19(01), P. 1 - 16
Published: March 1, 2024
A key biophysical process in biological systems, liquid–liquid phase separation (LLPS) is responsible for constructing membrane-less organelles and modulating cellular activities. The mechanisms underlying LLPS are explored this paper, with an emphasis on multivalent interactions, entropy-driven processes, how they affect organization. We investigate the impact of external stimuli behavior clarify physiological roles biomolecular condensates, from stress response modulation to gene expression regulation. In addition, we study dysregulated human disorders, providing information about possible therapeutic targets approaches innovative therapeutics. Through interdisciplinary approach, aim improve our knowledge its effects health illness, opening door new that focus proteins structure cells.
Language: Английский
Citations
1
Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(11), P. 6697 - 6699
Published: June 12, 2024
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTIntroduction: Molecular CrowdingAnnalisa Pastore*Annalisa PastoreImperial College London, South Kensington Campus, SW7 2AZ U.K.King's The Wohl Institute, 5 Cutcombe Rd, SW59RT U.K.Elettra Sincrotrone Trieste, Strada Statale 14 - km 163,5 in AREA Science Park, 34149 Basovizza, Italy*[email protected]More by Annalisa PastoreView Biographyhttps://orcid.org/0000-0002-3047-654X, Germán Rivas CaballeroGermán CaballeroCIB Margarita Salas − CSIC, Ramiro de Maeztu 9, 28040 Madrid, SpainMore CaballeroView Biographyhttps://orcid.org/0000-0003-3450-7478, and Piero Andrea TemussiPiero TemussiDipartimento di Scienze Chimiche, Università degli Studi Napoli Federico II, Via Cintia 21, 80126 Napoli, ItalyMore TemussiView Biographyhttps://orcid.org/0000-0001-6032-4291Cite this: Chem. Rev. 2024, 124, 11, 6697–6699Publication Date (Web):June 12, 2024Publication History Received15 April 2024Published online12 June inissue 12 2024https://pubs.acs.org/doi/10.1021/acs.chemrev.4c00287https://doi.org/10.1021/acs.chemrev.4c00287editorialACS PublicationsCopyright © Published 2024 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions free to access through this site. Learn MoreArticle Views414Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated reflect usage leading up last few days.Citations number other articles citing article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence for given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail (1 MB) Get e-AlertscloseSUBJECTS:Computational modeling,Genetics,Molecular dynamics simulations,Phase separation,Stress e-Alerts
Language: Английский
Citations
1
Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 336, P. 103361 - 103361
Published: Nov. 29, 2024
Language: Английский
Citations
1
Biophysical Journal, Journal Year: 2024, Volume and Issue: 123(10), P. 1165 - 1166
Published: April 15, 2024
Language: Английский
Citations
0