Optical Detection of Hydrogen Sulfide by Turn-ON Chemosensors Based on 2-Nitro-5,10,15,20-tetraphenylporphyrins DOI
Carla I. M. Santos,

Ana M. Santiago,

Cristina J. Dias

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112801 - 112801

Published: April 1, 2025

Language: Английский

Selenenylsulfide Bond as a General Scaffold for Constructing Thiol Probes with Enhanced Response Rate DOI
Tao Ma, Jintao Zhao, Bingbing Chang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Leveraging disulfide (-S-S-) or diselenide (-Se-Se-) units as triggers in the design of small-molecule fluorescent probes for detecting intracellular reductive species has demonstrated high efficacy. However, selenenylsulfides, which exhibit reactivity between diselenides and disulfides, remain relatively unexplored. In this work, we compare efficiency -S-S-, seleno-sulfur (-Se-S-), sulfur-selenium (-S-Se-) structural constructing thiol probes, disclose scaffold -Se-S- a versatile recognition site thiols, successfully apply unit to near-infrared (NIR) probe, ASC-SeS. The mechanism reveals that breaking bond leads selenolate, undergoes faster cyclization than corresponding thiolate is from cleavage -S-S- -S-Se- bond. Conjugation trigger with multiple NIR fluorophores validates general applicability linear selenenylsulfides accelerating response rate thiols. By harnessing superior responsiveness ASC-SeS, employ probe live cells vivo, elucidate severe depletion thiols drug-induced liver injury (DILI).

Language: Английский

Citations

0
A biodegradable and biocompatibile polymer-shell to develop a H2S sensing device. DOI Creative Commons

Alessio Trerotola,

Paola Rizzo,

Angela Erbaggio

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112786 - 112786

Published: March 1, 2025

Language: Английский

Citations

0
Monitoring variations in mitochondrial hydrogen sulfide using two-photon cyclometalated iridium(III) complex probe: A new strategy for ischemia-reperfusion drug discovery and efficacy evaluation DOI
Peng Du,

Tianao Zhang,

Ying Wu

et al.

Talanta, Journal Year: 2025, Volume and Issue: 292, P. 128021 - 128021

Published: March 30, 2025

Language: Английский

Citations

0
Simple Strategy to Develop Multifunctional NIR Fluorescent Probes for Simultaneous Identification of H2S and SO2 DOI
Wei Xing, Shuying Wu, Heng Liu

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

H2S and SO2 have been considered as important gaseous signaling molecules in biological systems, functioning regulatory roles many physiological processes of organisms. To better understand the crosstalk synergetic effects between developing a single fluorescent probe for dual-channel fast detection is highly urgent. We herein report simple strategy to develop multifunctional near-infrared (NIR) probes simultaneous identification SO2. Based on idea modulating reactivity benzopyrylium core with electron donors, two new NIR (SW1 SW2) were synthesized evaluated. The SW2 could not only rapidly sense different fluorescence signals but also be used reversible investigate flux H2O2 Moreover, was successfully applied visualizing living cells mice. These results suggest that serve useful tool understanding complex relationships systems.

Language: Английский

Citations

0
Optical Detection of Hydrogen Sulfide by Turn-ON Chemosensors Based on 2-Nitro-5,10,15,20-tetraphenylporphyrins DOI
Carla I. M. Santos,

Ana M. Santiago,

Cristina J. Dias

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112801 - 112801

Published: April 1, 2025

Language: Английский

Citations

0