Nanostructured Bubble Thin Films—From Simple Fabrication to Scalable Applications: A Review DOI Creative Commons
Naif Ahmed Alshehri

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(11), P. 868 - 868

Published: June 4, 2025

Several applications for nanotechnology necessitate the assembly of nanomaterials over large areas with precise orientation and density. Some techniques, such as Langmuir–Blodgett, contact printing, electric field directed assembly, flow-assisted alignment, have been used to meet a requirement. However, it remains uncertain whether these techniques can be scaling up nanomaterial thin films onto solid flexible substrates. Accordingly, this review paper addresses an issue by reviewing two recent scalable methods: blown bubble (BBFs) deposition method (BDM). It specifically offers comprehensive account film methods along their applications. also discusses how are made fabricate devices. finally provides some recommendations further research

Language: Английский

Metal–organic framework MIL-101(Fe) functionalized with folic acid as a multifunctional nanocarrier for targeted chemotherapy–photodynamic therapy DOI
Eman Serag, Esmail M. El‐Fakharany, Sherif Hammad

et al.

Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A novel folic acid-conjugated, iron-based metal framework MIL-101 (Fe) MOF loaded with 1,8-acridinediones (DO8) was developed for targeted photodynamic therapy (PDT).

Language: Английский

Citations

1

Engineered Photoactivatable Nanomicelles for Ferroptosis-like Combinational Tumor Therapy In Vitro and In Vivo DOI
Yandai Lin, Xinru Kong, Zhe Liu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Nitric oxide (NO)-based gas therapy has attracted increasing attention as a promising approach for tumor treatment, but elevated levels of glutathione (GSH) in the microenvironment significantly limit their therapeutic effectiveness. In this study, type engineered photoactivatable nanomicelles Ce6/NI@PEP@HA (CNPH) were developed combinational photodynamic and NO therapy. CNPH was capable targeted accumulation to tumors, where it depleted GSH released effectively produce reactive oxygen species (ROS) with oxidative damage under laser irradiation at 660 nm. The consumption induced deactivation peroxidase activity, leading enhanced toxic lipid peroxide enabled ferroptosis-like outcome. Additionally, effective production ROS resulted mitochondrial dysfunction, characterized by disruption membrane potential decreased adenosine triphosphate concentration. vivo animal experiments indicated that achieved inhibition 89.1%, proven be more strategy contrast any single modality. consequence, opened up new horizon cutting-edge noninvasive paradigm advanced treatments.

Language: Английский

Citations

0

Deciphering the tumor immune microenvironment: Microscale measurements for precision detection and multidimensional analysis DOI Creative Commons
Lu Wang,

Fan Yin,

Rongping Luo

et al.

View, Journal Year: 2025, Volume and Issue: unknown

Published: March 20, 2025

Abstract The precision of cancer immunotherapy is critically dependent on accurately characterizing the tumor immune microenvironment (TIME), which represents a complex interplay cellular components, cytokines, and metabolic factors. Traditional diagnostic methods lack resolution to capture dynamic molecular interactions within TIME at microscale level. This review focuses recent advancements in measurements for identifying novel immune‐oncology biomarkers therapeutic targets TIME, emphasizing importance high‐fidelity data infiltrates significance longitudinal high‐dimensional analysis predicting treatment responses. Furthermore, discusses impact reprogramming potential new responses immunotherapy. role nanotechnology enhancing detection checkpoints development AI‐based sensors real‐time predictive modeling also explored, highlighting these advanced technologies revolutionize field

Language: Английский

Citations

0

Fe3O4@Bi2S3 Nanoparticles Mediated MRI-Guided Precision Radiosensitization for Orthotopic Glioblastoma via External Magnetism DOI
Xiaowei Song, Liang Xiao, Lingling Xu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Radioresistance in tumors and the excess damage normal tissues during radiotherapy (RT) restrict clinical application of glioblastoma RT. Image-guided radiosensitization is hopefully adopted to achieve precision Nevertheless, therapeutic effect radiosensitizers unsatisfactory due limitations blood–brain barrier poor tumor targeting. Herein, Fe3O4@Bi2S3 nanoparticles coated with a cell membrane (denoted as FBM) have been designed sensitize FBM accumulates precisely within via external magnetism homologous adhesion capability. Afterward, releases high-Z atoms (Bismuth) ionizing radiation micro acidic environments that interact generate high densities secondary radiation, which leads enhanced dose deposits. Simultaneously, generates reactive oxygen species, lipid peroxidation Fe2+, depletes glutathione, downregulates glutathione peroxidase 4 activate ferroptosis. Notably, growth inhibition rate FBM-mediated RT increases 75.49% orthotopic model. Besides, magnetic resonance imaging performance shows potential diagnosis therapy surveillance, thereby reducing adjacent realizing MRI-guided Hence, novel multifunctional nanoplatform offers for image-guided induced by activating ferroptosis, thus presenting an efficient radiotherapeutic approach glioblastoma.

Language: Английский

Citations

0

Manganese(III)-containing ionic liquids with liquid crystalline properties: Synthesis, structural insights, and functional applications DOI
Nazmun Sharmin, Md. Hafizul Islam, Md. Hafizul Islam

et al.

Next Materials, Journal Year: 2025, Volume and Issue: 8, P. 100682 - 100682

Published: May 9, 2025

Language: Английский

Citations

0

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics DOI Creative Commons
Jingyu Shi, Yadi Fan, Qin Zhang

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 16, 2025

Abstract The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment monitoring diseases. Photo‐energy conversion‐based nanomaterials have emerged as versatile that utilizes unique properties light activate with high spatial temporal precision. This review provides comprehensive overview recent developments in photo‐energy conversion using nanomaterials, highlighting their applications disease theranostics. discussion begins by exploring fundamental principles including types materials used various light‐triggered mechanisms, such photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered SERS, photodynamic processes. Following this, delves broad spectrum emphasizing role diagnosis major diseases, cancer, neurodegenerative disorders, retinal degeneration, osteoarthritis. Finally, challenges opportunities technologies are discussed, aiming advance personalized medicine.

Language: Английский

Citations

0

Smart nanomaterials for multimodal theranostics and tissue regeneration DOI
Hyun Lee, Kyoung Sub Kim, Iman Zare

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 541, P. 216801 - 216801

Published: May 17, 2025

Language: Английский

Citations

0

Promising biomedical applications using superparamagnetic nanoparticles DOI Creative Commons
Yosri A. Fahim, Ibrahim W. Hasani,

Waleed Mahmoud Ragab

et al.

European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)

Published: June 2, 2025

Abstract Magnetic nanoparticles (MNPs) have emerged as powerful tools in biomedicine due to their distinct physicochemical characteristics, including a high surface-area-to-volume ratio, adjustable size, magnetic sensitivity, and compatibility with biological systems. These properties enable precise control through external fields, making MNPs highly effective targeted therapeutic diagnostic applications. Although not inherently intelligent, they can exhibit programmable responsive behavior under influence, enhancing utility drug delivery hyperthermia-based treatments. In the medical field, been extensively explored for role resonance imaging (MRI) enhancement, selective transport, hyperthermia cancer therapy, biomolecular separation. Within oncology, facilitate direct of compounds tumors, reducing systemic side effects increasing treatment specificity. Additionally, capacity produce localized heat when exposed alternating fields makes them instrumental where malignant cells are selectively eradicated. A key advantage is adaptable surface chemistry, which allows functionalization biocompatible polymers, ligands, other stabilizing agents. modifications enhance stability, minimize immune responses, optimize performance physiological environments. Functionalized contributed significantly improving MRI contrast, refining mechanisms, effectiveness This review examines recent breakthroughs MNP-based technologies, an emphasis on tumor targeting, across blood–brain barrier,

Language: Английский

Citations

0

Nanostructured Bubble Thin Films—From Simple Fabrication to Scalable Applications: A Review DOI Creative Commons
Naif Ahmed Alshehri

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(11), P. 868 - 868

Published: June 4, 2025

Several applications for nanotechnology necessitate the assembly of nanomaterials over large areas with precise orientation and density. Some techniques, such as Langmuir–Blodgett, contact printing, electric field directed assembly, flow-assisted alignment, have been used to meet a requirement. However, it remains uncertain whether these techniques can be scaling up nanomaterial thin films onto solid flexible substrates. Accordingly, this review paper addresses an issue by reviewing two recent scalable methods: blown bubble (BBFs) deposition method (BDM). It specifically offers comprehensive account film methods along their applications. also discusses how are made fabricate devices. finally provides some recommendations further research

Language: Английский

Citations

0