Advanced Synthesis & Catalysis,
Journal Year:
2018,
Volume and Issue:
361(5), P. 1124 - 1129
Published: Dec. 15, 2018
Abstract
An
efficient
visible‐light‐induced
α‐oxidation
of
N
‐substituted
tetrahydroisoquinolines
to
dihydroisoquinolones
has
been
developed
using
eosin
Y
as
an
organo‐photocatalyst
and
oxygen
a
green
oxidant.
The
reactions
were
carried
out
under
mild
reaction
conditions;
the
desired
obtained
in
up
96%
yield
at
room
temperature
atmosphere.
This
transformation
provides
convenient
route
with
wide
range
substrates.
magnified
image
Chemical Society Reviews,
Journal Year:
2021,
Volume and Issue:
50(14), P. 8067 - 8101
Published: Jan. 1, 2021
Molecular
oxygen
as
a
green,
inexpensive
oxidant
and
source
has
displayed
lots
of
advantages
compared
to
other
oxidants.
This
review
introduces
the
recent
advances
radical
processes
in
molecular
oxygen-mediated
oxygenation
reactions.
Chemical Society Reviews,
Journal Year:
2020,
Volume and Issue:
49(15), P. 5310 - 5358
Published: Jan. 1, 2020
This
review
highlights
the
developments
in
iron
and
cobalt
catalyzed
C(sp3)–H
bond
functionalization
reactions
with
emphasis
on
their
applications
organic
synthesis,
i.e.
natural
products
pharmaceuticals
synthesis
and/or
modification.
Nature Communications,
Journal Year:
2021,
Volume and Issue:
12(1)
Published: Jan. 20, 2021
Abstract
Recently,
with
the
boosted
development
of
radical
chemistry,
enantioselective
functionalization
C(
sp
3
)–H
bonds
via
a
pathway
has
witnessed
renaissance.
In
principle,
two
distinct
catalytic
modes,
distinguished
by
steps
in
which
stereochemistry
is
determined
(the
formation
step
or
step),
can
be
devised.
This
Perspective
discusses
state-of-the-art
area
involving
intermediates
as
well
future
challenges
and
opportunities.
Chemical Society Reviews,
Journal Year:
2023,
Volume and Issue:
53(1), P. 137 - 162
Published: Nov. 29, 2023
Natural
metalloenzymes
with
astonishing
reaction
activity
and
specificity
underpin
essential
life
transformations.
Nevertheless,
enzymes
only
operate
under
mild
conditions
to
keep
sophisticated
structures
active,
limiting
their
potential
applications.
Artificial
that
recapitulate
the
catalytic
of
can
not
circumvent
enzymatic
fragility
but
also
bring
versatile
functions
into
practice.
Among
them,
metal-organic
frameworks
(MOFs)
featuring
diverse
site-isolated
metal
sites
supramolecular
have
emerged
as
promising
candidates
for
move
toward
unparalleled
properties
behaviour
enzymes.
In
this
review,
we
systematically
summarize
significant
advances
in
MOF-based
metalloenzyme
mimics
a
special
emphasis
on
active
pocket
engineering
at
atomic
level,
including
primary
secondary
coordination
spheres.
Then,
deep
understanding
mechanisms
advanced
applications
are
discussed.
Finally,
perspective
emerging
frontier
research
is
provided
advance
bioinspired
catalysis.
Chemical Society Reviews,
Journal Year:
2020,
Volume and Issue:
49(22), P. 8137 - 8155
Published: Jan. 1, 2020
Biocatalytic
methods
for
selective
C–H
oxyfunctionalization
reactions
are
rapidly
emerging
and
hold
significant
potential
to
streamline
complex
molecule
synthesis.
This
review
highlights
key
advances
in
this
area
developed
within
the
past
decade.
Chemical Science,
Journal Year:
2019,
Volume and Issue:
10(48), P. 10974 - 10978
Published: Jan. 1, 2019
The
Dakin
and
Baeyer-Villiger
(BV)
oxidation
reactions
require
addition
of
peroxides
as
oxidants
an
acid
or
a
base
catalyst.
Reaction
times
range
from
hours
to
days
obtain
target
products.
Previously,
we
reported
that
hydrogen
peroxide
(H2O2)
is
spontaneously
generated
in
water
microdroplets
without
any
added
chemicals
applied
electrical
potential.
Here,
report
the
BV
occur
modest
yields
within
milliseconds
aqueous
at
room-temperature
external
catalysts.
H2O2
generation
result
special
environment
microdroplet
surface,
which
promotes
autoionization.
We
find
increasing
content
decreasing
droplet
size
improve
product
yield
reactions,
supporting
contention
amount
could
induce
two
near
air-water
interface
surface.
Biology,
Journal Year:
2018,
Volume and Issue:
7(3), P. 42 - 42
Published: Aug. 2, 2018
Flavoprotein
monooxygenases
create
valuable
compounds
that
are
of
high
interest
for
the
chemical,
pharmaceutical,
and
agrochemical
industries,
among
others.
Monooxygenases
use
flavin
as
cofactor
either
single-
or
two-component
systems.
Here
we
summarize
current
knowledge
about
adenine
dinucleotide
(FAD)-dependent
describe
their
biotechnological
relevance.
Two-component
FAD-dependent
catalyze
hydroxylation,
epoxidation,
halogenation
reactions
physiologically
involved
in
amino
acid
metabolism,
mineralization
aromatic
compounds,
biosynthesis
secondary
metabolites.
The
monooxygenase
component
these
enzymes
is
strictly
dependent
on
reduced
FAD,
which
supplied
by
reductase
component.
More
more
representatives
have
been
discovered
characterized
recent
years,
has
resulted
identification
novel
physiological
roles,
functional
properties,
a
variety
biocatalytic
opportunities.
Green Chemistry,
Journal Year:
2020,
Volume and Issue:
22(13), P. 4357 - 4363
Published: Jan. 1, 2020
A
light
and
oxygen-enabled
sodium
trifluoromethanesulfinate-mediated
selective
oxidation
of
C–H
bonds
has
been
developed.
High-value-added
aromatic
ketones
carboxylic
acids
were
easily
prepared
in
high-to-excellent
yields
using
readily
available
starting
materials.
