International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(24), P. 13391 - 13391
Published: Dec. 13, 2021
In
the
present
work,
a
convenient
and
straightforward
approach
to
preparation
of
borylated
amidines
based
on
closo-dodecaborate
anion
[B12H11NCCH3NHR]−,
R=H,
Alk,
Ar
was
developed.
This
method
has
two
stages.
A
nitrile
derivative
general
form
[B12H11NCCH3]−
obtained,
using
modified
technique,
in
first
stage.
On
second
stage
resulting
molecular
system
interacted
with
primary
amines
target
amidine
products.
is
characterised
by
simple
chemical
apparatus,
mild
conditions
high
yields
final
The
mechanism
addition
amine
studied,
quantum-chemical
methods.
interaction
between
NH3
ammonia
chosen
as
an
example.
It
found
that
structure
transition
state
determines
stereo-selectivity
process.
study
biological
properties
sodium
salts
indicated
substances
had
low
toxicity
could
accumulate
cancer
cells
significant
amounts.
Journal of the American Chemical Society,
Journal Year:
2020,
Volume and Issue:
142(22), P. 9890 - 9895
Published: May 12, 2020
Described
herein
is
the
first
iridium-catalyzed
cyclative
indenylation
through
sequential
B(4)–C
and
intramolecular
C–C
bond
formation
from
o-carboranes
propargyl
alcohols,
leading
to
of
B(4)-indenylated
with
excellent
regioselectivity
via
direct
B–H
activation.
Moreover,
regioselective
1,3-dienylation
has
been
accessed
activation,
dehydration,
decarboxylation,
producing
B(4)-dienylated
o-carboranes.
Journal of the American Chemical Society,
Journal Year:
2019,
Volume and Issue:
142(1), P. 327 - 334
Published: Nov. 29, 2019
For
decades,
chemists
have
strived
to
mimic
the
intricate
design
and
diverse
functions
of
naturally
occurring
systems
through
bioinspired
synthesis
programmable
inorganic
nanomaterials.
The
development
thiol-capped
gold
nanoparticles
(AuNPs)
has
driven
advancement
in
this
area;
however,
although
versatile
readily
accessible,
hybrid
AuNPs
are
rarely
atomically
precise,
which
limits
control
over
their
surface
topology
therefore
study
complex
structure–function
relationships.
Here,
we
present
a
bottom-up
approach
systematic
assembly
precise
nanoclusters
employing
strategy
that
mimics
synthetic
ease
with
normally
constructed,
while
producing
well-defined
covalent
nanoscale
assemblies
topologies.
first
time,
using
structurally
characterized
cluster-based
organometallic
building
block,
demonstrate
multivalent
binding
capabilities
protein
targets.
Journal of the American Chemical Society,
Journal Year:
2020,
Volume and Issue:
142(15), P. 6940 - 6945
Published: March 31, 2020
Copper-catalyzed
electrochemical
selective
cage
B–H
oxygenation
of
o-carboranes
has
been
achieved
for
the
first
time.
Under
a
constant
electric
current
(4.0
mA)
at
room
temperature,
copper-catalyzed
cross-coupling
carboranyl
amides
with
lithium
phenolates
results
in
formation
B(4,5)-diphenolated
via
direct
activation,
whereas
use
tert-butoxide
affords
B(4)-monooxygenated
products.
This
reaction
does
not
require
any
additional
chemical
oxidants
and
generates
H2
salt
as
byproducts.
Control
experiments
indicated
that
high-valent
Cu(III)
species
is
likely
involved
process.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(24), P. 13391 - 13391
Published: Dec. 13, 2021
In
the
present
work,
a
convenient
and
straightforward
approach
to
preparation
of
borylated
amidines
based
on
closo-dodecaborate
anion
[B12H11NCCH3NHR]−,
R=H,
Alk,
Ar
was
developed.
This
method
has
two
stages.
A
nitrile
derivative
general
form
[B12H11NCCH3]−
obtained,
using
modified
technique,
in
first
stage.
On
second
stage
resulting
molecular
system
interacted
with
primary
amines
target
amidine
products.
is
characterised
by
simple
chemical
apparatus,
mild
conditions
high
yields
final
The
mechanism
addition
amine
studied,
quantum-chemical
methods.
interaction
between
NH3
ammonia
chosen
as
an
example.
It
found
that
structure
transition
state
determines
stereo-selectivity
process.
study
biological
properties
sodium
salts
indicated
substances
had
low
toxicity
could
accumulate
cancer
cells
significant
amounts.
