Aerobic Microbial Transformation of Fluorinated Liquid Crystal Monomer: New Pathways and Mechanism DOI

Xifen Zhu,

Yuanyuan Yu,

Weikun Meng

et al.

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 58(1), P. 510 - 521

Published: Dec. 15, 2023

Fluorinated liquid crystal monomers (FLCMs) have been suggested as emerging contaminants, raising global concern due to their frequent occurrence, potential toxic effects, and endurance capacity in the environment. However, environmental fate of FLCMs remains unknown. To fill this knowledge gap, we investigated aerobic microbial transformation mechanisms an important FLCM, 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3, 5-difluoro-4′-propylbiphenyl (DTMDPB), using enrichment culture termed BG1. Our findings revealed that 67.5 ± 2.1% initially added DTMDPB was transformed 10 days under optimal conditions. A total 14 products obtained a series reactions (e.g., reductive defluorination, ether bond cleavage, demethylation, oxidative hydroxylation aromatic ring opening, sulfonation, glucuronidation, O-methylation, thiolation) were identified. Consortium BG1 harbored essential genes could transform DTMDPB, such dehalogenation-related [e.g., glutathione S-transferase gene (GST), 2-haloacid dehalogenase (2-HAD), nrdB, nuoC, nuoD]; hydroxylating-related hcaC, ubiH, COQ7; opening-related ligB catE; methyltransferase ubiE ubiG. Two DTMDPB-degrading strains isolated, which are affiliated with genus Sphingopyxis Agromyces. This study provides novel insight into FLCMs. The implications for development bioremediation strategies aimed at addressing sites contaminated

Language: Английский

Percutaneous penetration of typical Organophosphate esters under catalysis by Carboxylesterase: Characteristics, mechanism and prediction model DOI Creative Commons
Yang Yan, Yuan-Qiao Hou, Yonglong Liao

et al.

Environment International, Journal Year: 2025, Volume and Issue: unknown, P. 109419 - 109419

Published: March 1, 2025

Language: Английский

Citations

0
Environmental behavior, toxic potencies, and risks of liquid crystal monomers: A critical review DOI

Jiawei Cheng,

Xiaojuan Li, Yawen Yuan

et al.

Critical Reviews in Environmental Science and Technology, Journal Year: 2024, Volume and Issue: 54(24), P. 1902 - 1919

Published: July 11, 2024

Language: Английский

Citations

3
Determination of potential dermal exposure rates of phosphorus flame retardants via the direct contact with a car seat using artificial skin DOI

Mai Shindo,

Maho Ishida,

Masahiro Tokumura

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 353, P. 141555 - 141555

Published: Feb. 26, 2024

Language: Английский

Citations

2
Current status and perspectives for 3D biomimetic epidermal tissue: From tissue reconstruction to biomedical application DOI

Shengsheng He,

Zhiyuan Wang, Rui Wang

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 97, P. 105722 - 105722

Published: April 26, 2024

Language: Английский

Citations

2
A review of liquid crystal monomers (LCMs) as emerging contaminants: Environmental occurrences, emissions, exposure routes and toxicity DOI
Yulin Wang, Qianqian Jin, Huiju Lin

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 135894 - 135894

Published: Sept. 19, 2024

Language: Английский

Citations

2
Comprehensive Characterization of Organic Light-Emitting Materials in Breast Milk by Target and Suspect Screening DOI
Shuping Zheng, Jingsheng Wang, Kai Luo

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(11), P. 5103 - 5116

Published: March 6, 2024

Organic light-emitting materials (OLEMs) are emerging contaminants in the environment and have been detected various samples. However, limited information is available regarding their contamination within human body. Here, we developed a novel QuEChERS (quick, easy, cheap, effective, rugged, safe) method coupled with triple quadrupole/high-resolution mass spectrometry to determine OLEMs breast milk samples, employing both target suspect screening strategies. Our analysis uncovered presence of seven out 39 targeted comprising five liquid crystal monomers two commonly used organic diode displays. The cumulative concentrations each sample ranged from ND 1.67 × 103 ng/g lipid weight, mean median concentration 78.76 0.71 respectively, which were higher compared that typical pollutants such as polychlorinated biphenyls polybrominated diphenyl ethers. We calculated estimated daily intake (EDI) rates for infants aged 0–12 months, EDI during lactation range 30.37 54.89 ng/kg bw/day. Employing approach, additionally identified 66 potential OLEMs, them, cholesteryl hydrogen phthalate benzoate, further confirmed using pure reference standards. These substances belong cholesteric raise concerns about endocrine-disrupting effects, indicated by silico predictive models. Overall, our present study established robust identification shedding light on findings indicate exposure should be investigated, including health risks.

Language: Английский

Citations

1
First Report on the Trophic Transfer and Priority List of Liquid Crystal Monomers in the Pearl River Estuary DOI

Yiye Jiang,

Yan‐Hong Zeng, Ling Long

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(36), P. 16131 - 16141

Published: Aug. 27, 2024

Liquid crystal monomers (LCMs) are emerging organic pollutants due to their potential persistence, toxicity, and bioaccumulation. This study first characterized the levels compositions of 19 LCMs in organisms Pearl River Estuary (PRE), estimated bioaccumulation trophic transfer potential, identified priority contaminants. were generally accumulated from sediment, LCM concentrations all ranged 32.35 1367 ng/g lipid weight. The main biphenyls analogues (BAs) (76.6%), followed by cyanobiphenyls (CBAs) (15.1%), least fluorinated (FBAs) (11.2%). most abundant BAs, FBAs, CBAs 1-(4-propylcyclohexyl)-4-vinylcyclohexane 1-ethoxy-2,3-difluoro-4-(4-(4-propylcyclohexyl) cyclohexyl) benzene (EDPBB, 10.1%), 4'-propoxy-4-biphenylcarbonitrile (5.1%), respectively. niche studies indicated that PRE food web was composed terrestrial-based diet marine chains. Most exhibited biodilution chains, except for EDPBB 4,4'-bis(4-propylcyclohexyl) biphenyl (BPCHB). hydrophobicity, position fluorine substitution LCMs, biological habits may be important factors affecting LCMs. BPCHB, 1-(prop-1-enyl)-4-(4-propylcyclohexyl) cyclohexane, as reports processes mechanisms biomonitoring PRE.

Language: Английский

Citations

1
Liquid Crystal Monomers in Human, Dog and Cat Feces from the United States DOI
Yuan Liu, Kurunthachalam Kannan

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136144 - 136144

Published: Oct. 11, 2024

Language: Английский

Citations

1
Identifying the toxic mechanisms of emerging electronic contaminations liquid crystal monomers and the construction of a priority control list for graded control DOI
Wei He, Hao Yang, Yunxiang Li

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175398 - 175398

Published: Aug. 14, 2024

Language: Английский

Citations

1
Evaluating the Environmental Persistence of Liquid Crystal Monomers Indoors and Outdoors DOI

Paola Miramontes Gonzalez,

Li Li

Environmental Science & Technology Letters, Journal Year: 2023, Volume and Issue: 11(3), P. 216 - 222

Published: Dec. 26, 2023

Liquid crystal monomers (LCMs) exemplify a group of chemicals prevalent in indoor environments. However, current frameworks for assessing the environmental persistence predominantly focus on outdoor environments, often overlooking Here, we model and compare LCMs across multimedia Our findings reveal that, when assessed an context, <10% investigated exhibit overall comparable to those persistent organic pollutants regulated by Stockholm Convention, one-third two-thirds meet Convention's medium-specific half-life thresholds persistence. found notable disparity between persistence: Approximately 90% demonstrate substantially prolonged indoors, 10 times longer average, up ∼150 some cases, compared outdoors. This long is mainly attributed low volatility their high affinity surface compartments. work highlights environment's role as both continuous source human exposure potential reservoir long-term regional contamination. Therefore, tailored, fit-for-purpose assessment "indoor persistence", focusing carries profound implications ecological health.

Language: Английский

Citations

3