Industrial
activities
are
a
major
source
of
organophosphorus
flame
retardants
(OPFRs)
and
plasticizers
in
aquatic
environments.
This
study
investigated
the
distribution
40
OPFRs
river
impacted
by
industrial
manufacturing
plants
Eastern
China
target
analysis.
Nontarget
analysis
using
high-resolution
mass
spectrometry
was
further
employed
to
identify
novel
compounds
(NOPs).
Thirty-four
were
detected
water
samples,
with
total
concentrations
62.9–1.06
×
103
ng/L
(median:
455
ng/L).
Triphenylphosphine
oxide
diphenyl
phosphoric
acid
ubiquitously
up
620
127
ng/L,
respectively.
Among
26
identified
NOPs,
17
reported
for
first
time
environment,
including
14
organophosphate
esters
(especially
4
heterocycles
3
oligomers),
2
organophosphites,
an
organophosphonate.
Bis(2,4-di-tert-butylphenyl)
hydrogen
phosphate
2,2-dimethylpropoxy(propyl)phosphinic
high
predicted
persistence
or
toxicity
widely
detected,
semiquantified
990
1.0
Structurally
similar
exhibited
consistent
variation
trends,
suggesting
common
emission
source.
Estimated
annual
discharges
sea
20.6–37.0
kg/yr
30.8–161
NOPs.
These
findings
indicate
that
contribute
NOPs
catchment
its
estuary,
posing
ecological
risks
both
terrestrial
marine
Organophosphorus
compounds
(OPCs)
pose
potential
hazards
to
human
health
and
aquatic
ecosystems.
However,
limited
knowledge
of
emerging
OPCs
beyond
organophosphate
esters
(OPEs)
hinders
a
thorough
understanding
the
environmental
occurrence
exposure
risks.
Through
target,
suspect,
nontarget
screening
analysis,
64
were
successfully
identified
in
Chinese
estuarine
waters,
including
24
known
OPEs
40
analogues
(i.e.,
quaternary
phosphonium,
phosphine
oxide,
organophosphonate,
organothiophosphate
esters).
Domestic
wastewater
agricultural
industrial
discharges
factors
influencing
OPC
distribution
patterns.
In
particular,
phosphoniums
oxides
accounted
for
over
50%
total
loading
Yellow
Jia
Rivers,
which
likely
polluted
by
phosphorus-related
industries.
Risk
quotient
(RQ)
calculations
showed
that
tetrabutylphosphonium
contributed
most
algae
toxicity
due
biocidal
effects
onium
salts,
while
chloroalkyl
dominated
ecological
risks
daphnia
fish.
The
multicriteria
decision
analysis
approach
was
further
introduced
relative
chemical
ranking
considering
variations
hazard
criteria
occurrence,
fate,
OPCs.
results
indicate
aryl
have
priority
similar
and,
therefore,
require
more
attention.
Environment International,
Journal Year:
2025,
Volume and Issue:
unknown, P. 109445 - 109445
Published: April 1, 2025
Organophosphorus
flame
retardants
and
plasticizers
(OPFRs)
are
prevalent
raise
health
concerns
due
to
their
endocrine-disrupting
properties.
Clinically
detectable
thyroid
nodules
less
common
in
children
than
adults
but
pose
a
higher
malignancy
risk.
The
effects
of
OPFRs
on
children's
relation
oxidative
stress
remain
unknown.
This
cross-sectional
study
analyzed
concentrations
seven
three
biomarkers
(OSBs),
namely
8-oxo-7,8-dihydro-2'-deoxyguanosine
(8-OHdG),
malondialdehyde,
o,
o'-dityrosine
(diY)
521
urine
samples
from
coastal
urbanized
region.
Median
creatinine-adjusted
levels
the
ranged
0.02
0.64
μg/g.
Triphenyl
phosphine
oxide
(TPPO)
was
detected
for
first
time
urine.
Diphenyl
phosphate
(DPHP)
isopropyl
phenyl
(ip-PPP)
were
frequently
detected,
with
median
0.46
μg/g
μg/g,
respectively.
Multiple
linear
regression
analyses
mixture
models
demonstrated
that
positively
associated
OSBs.
Furthermore,
logistic
analysis
revealed
urinary
TPPO
tris(1-chloro-2-propyl)
(TCIPP)
nodule
risk
children,
TCIPP
further
sex-dependent
association
particularly
girls,
although
OSBs
did
not
show
significant
mediating
effects.
Overall,
studies
warranted
explore
potential
mechanisms
linking
exposure
stress,
children.
Environmental Science & Technology,
Journal Year:
2024,
Volume and Issue:
58(39), P. 17441 - 17453
Published: Sept. 19, 2024
This
study
provides
a
comprehensive
investigation
into
the
structure-dependent
uptake,
distribution,
biotransformation,
and
potential
toxicity
effects
of
alkyl
organophosphate
esters
(OPEs)
in
hydroponic
lettuce
(
