Comprehensive Analysis beyond Traditional Organophosphate Esters (OPEs) Uncovers the Prevalence of Novel OPEs and Related Compounds in River Waters DOI
Jingrun Hu, Yi Liu,

Yitao Lyu

et al.

ACS ES&T Water, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 24, 2024

This study aims to comprehensively characterize the occurrence and potential risks of organophosphate esters (OPEs), especially novel OPEs related compounds present in river waters. Using high-resolution mass spectrometry, we conducted a comprehensive analysis OPE-related water samples (n = 90) from Chaobai River Beijing, China. Target screening detected 16 traditional with cumulative concentrations 0.69–1315 ng/L spring 1.5–1218 autumn samples. Suspect nontarget further identified 42 compounds, including 12 triesters, 11 diesters, 7 organophosphonates, 8 organothiophosphate esters, 4 others. The semiquantified these make up, on average, 36% all compounds. Thereinto, 36 were discovered surface for first time. Downstream exhibited more complex OPE profiles higher compared upstream reservoir samples, associated varied watershed characteristics. Hazard assessment risk-based prioritization revealed significant environmental concerns regarding certain chlorinated such as bis((5-ethyl-2-methyl-1,3,2-dioxaphosphorinan-5-yl)methyl) methyl phosphonate P,P'-dioxide, 2-ethylhexyl hydrogen (2-ethylhexyl)phosphonate, dihexyl phosphate. underscores importance understanding contamination water.

Language: Английский

Secondary organophosphate esters: A review of environmental source, occurrence, and human exposure DOI
Xinkai Wang, Yuan Xue, Xianming Zhang

et al.

Critical Reviews in Environmental Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Sept. 12, 2024

Language: Английский

Citations

2
Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment DOI Creative Commons
Meng Gao, Yu Wang, Lai Wei

et al.

Environment International, Journal Year: 2024, Volume and Issue: 195, P. 109205 - 109205

Published: Dec. 11, 2024

Language: Английский

Citations

1
Effect of nitrogen oxides and sulfur oxides to triphenyl phosphate degradation and cytotoxicity on surface of different transition metal salts DOI

Wulve Fan,

Zhiliang Zhu, Xiaochang Liu

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 946, P. 174422 - 174422

Published: July 3, 2024

Language: Английский

Citations

1
A Novel Organophosphate Ester, Tris(2,4-ditert-butylphenyl) Phosphate, Induced Reproductive Toxicity in Male Zebrafish at Environmentally Relevant Concentrations DOI
Yongkang Zhang,

Haiyu Qin,

Boqun Li

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 24, 2024

As a novel organophosphate ester (NOPE), tris(2,4-ditert-butylphenyl) phosphate (TDtBPP) has attracted significant attention due to its unexpectedly high detection in natural environments. However, the ecological toxic effects of environmentally relevant concentrations TDtBPP organisms remain entirely unknown. In this study, 1 month old zebrafish were exposed 0, 50, 500, or 5000 ng/L for 150 days, and reproductive toxicity male fish was evaluated. Results demonstrated that exposure significantly inhibited maturation spermatozoa thus decreased spermatogenesis. Furthermore, abnormal sperm morphology motility also observed. The decrease quantity quality eventually resulted declining fecundity. Moreover, downregulated expression hsd3b1 vivo vitro subsequently synthesis androgens testes Leydig cells. This inhibition androgen appeared be responsible observed fish. Molecular docking dual-luciferase reporter gene experiments elucidated promotion vitamin D on transcription by receptor hsd3b1. Our findings provide first time evidence poses risk reproduction at levels.

Language: Английский

Citations

1
Nationwide Profiling and Source Identification of Organophosphate Esters in Korean Surface Waters Using Target, Suspect, and Non-Target HRMS Analysis DOI
Daeho Kang,

Heewon Jang,

Sori Mok

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: unknown, P. 143579 - 143579

Published: Oct. 1, 2024

Language: Английский

Citations

0
Aqueous secondary formation substantially contributes to organophosphate esters in aerosols DOI Creative Commons
Gan Zhang,

Shaojun Lv,

Lele Tian

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Abstract Chemicals of emerging concern (CECs), like organophosphate esters (OPEs), are toxic substances threatening human/wildlife health. Yet the atmospheric transformation CECs remains poorly understood. Here we combine field measurements and partitioning models to test hypothesis that secondary formation OPEs could be enhanced by heterogenous processes in aerosols. We found hydrophobic absorbed favorably into organic phase, whereas hydrophilic preferably partition aqueous phase. provide evidence occurs winter, magnitude is strongly dependent on aerosol water content. suggest dissolved inorganic salts transitional metals aerosols impact positively particle-bound OPEs, facilitating their and/or oxidation. Our findings highlight important role oxidation chemistry for fate atmosphere, urging a better consideration products future risk assessment chemicals management.

Language: Английский

Citations

0
Comprehensive Analysis beyond Traditional Organophosphate Esters (OPEs) Uncovers the Prevalence of Novel OPEs and Related Compounds in River Waters DOI
Jingrun Hu, Yi Liu,

Yitao Lyu

et al.

ACS ES&T Water, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 24, 2024

This study aims to comprehensively characterize the occurrence and potential risks of organophosphate esters (OPEs), especially novel OPEs related compounds present in river waters. Using high-resolution mass spectrometry, we conducted a comprehensive analysis OPE-related water samples (n = 90) from Chaobai River Beijing, China. Target screening detected 16 traditional with cumulative concentrations 0.69–1315 ng/L spring 1.5–1218 autumn samples. Suspect nontarget further identified 42 compounds, including 12 triesters, 11 diesters, 7 organophosphonates, 8 organothiophosphate esters, 4 others. The semiquantified these make up, on average, 36% all compounds. Thereinto, 36 were discovered surface for first time. Downstream exhibited more complex OPE profiles higher compared upstream reservoir samples, associated varied watershed characteristics. Hazard assessment risk-based prioritization revealed significant environmental concerns regarding certain chlorinated such as bis((5-ethyl-2-methyl-1,3,2-dioxaphosphorinan-5-yl)methyl) methyl phosphonate P,P'-dioxide, 2-ethylhexyl hydrogen (2-ethylhexyl)phosphonate, dihexyl phosphate. underscores importance understanding contamination water.

Language: Английский

Citations

0