Impact of molecular structure on the biological removal efficiency of fluoroquinolone antibiotics: An in-silico approach DOI
Wenyu Xiao, Zhaoyong Bian

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 956, P. 177178 - 177178

Published: Nov. 6, 2024

Language: Английский

Effects of polystyrene microplastic composite with florfenicol on photosynthetic carbon assimilation of rice (Oryza sativa L.) seedlings: Light reactions, carbon reactions, and molecular metabolism DOI

Luoqin Shen,

Zhiheng Li,

Xinting Huang

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 478, P. 135470 - 135470

Published: Aug. 9, 2024

Language: Английский

Citations

4

Multiomics Analysis Reveals Key Targeted Metabolic Pathways Underlying the Hormesis and Detrimental Effects of Enrofloxacin on Rice Plants DOI
Lili Chen,

Zelong Xu,

Yuqing He

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Fluoroquinolone antibiotic enrofloxacin (ENR) is frequently detected in agricultural environments. The hormesis and detrimental effects of ENR on crops have been extensively observed. However, the molecular mechanisms underlying these crops' responses to remain limited. Here, integrated physiological, transcriptomic, metabolomic analysis revealed key metabolic pathway ENR-induced rice. results showed that mainly affected three pathways: 'biosynthesis amino acids', "tryptophan metabolism", 'phenylpropanoid/flavonoid biosynthesis'. A low level treatment promoted root elongation enhanced antioxidant capacity by increasing phytohormone gibberellin A3 flavonol quercetin-3-O-neohesperidoside, respectively. high dose significantly stimulated ROS production, inhibited photosynthesis, ultimately impaired plant growth. In response toxicity, plants accumulated more quercetin derivatives as antioxidants produced defense-related substances, such N-hydroxytryptamine, indole-3-acetonitrile, jasmonic acid, combat biotic stress. conclusion, this study provides new insights into mechanism accounting for ecological pollution farmland.

Language: Английский

Citations

0

Herbicide prometryn aggravates the detrimental effects of heat stress on the potential for mutualism of Symbiodiniaceae DOI

Yanyu Zhou,

Fucun Liu,

Meile Yuan

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 137389 - 137389

Published: Jan. 1, 2025

Language: Английский

Citations

0

Design, synthesis, and biological evaluation of oxime ether derivatives containing 1,5‐dimethyl‐6‐thioxo‐1,3,5‐triazinane‐2,4‐dione as protoporphyrinogen IX oxidase inhibitors DOI Open Access

Dingfeng Luo,

Yuanhui Wan,

Yingying Wang

et al.

Pest Management Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Abstract BACKGROUND Herbicides based on protoporphyrinogen IX oxidase (PPO; EC 1.3.3.4) are widely used for weeding control in agricultural fields to safeguard food security. PPO herbicides, because of their low dosage, rapid action weeds, slow accumulation the environment and toxicity mammals, have become an important field research development new herbicides. This study presents a novel molecular scaffold with remarkably potent herbicidal activity. RESULTS A series oxime ether derivatives containing 1,5‐dimethyl‐6‐thioxo‐1,3,5‐triazinane‐2,4‐dione 6a–6z were designed synthesized bioisosterism substructure splicing, characterized by 1 H 13 C nuclear magnetic resonance spectroscopies, high‐resolution mass spectrometry. The configuration compound 6u was confirmed single‐crystal X‐ray diffraction. Compound 6r displayed excellent activity >95% against Echinochloa crus‐galli , Digitaria sanguinalis Medicago sativa Conyza canadensis at dosage 37.5 g hm–2 glasshouse. At 75 hm–2, safe application rice showed (>200 μg g–1) towards Apis mellifera . Transcriptomics analysis E. treated using oxadiazon as positive control, revealed compound's mode‐of‐action. There eight metabolic biosynthetic pathways DEGs ‘photosynthesis’, ‘porphyrin metabolism’, ‘carotenoid biosynthesis’ so between same. Scaffold94.443 (coproporphyrinogen‐III oxidase) upstream changes downregulated quantitative reverse transcription PCR combined chlorophyll biosynthesis. target may be Nt inhibitory effects, represented K i, 30.34 n m vitro Molecular docking that could form two hydrogen bonds Arg98. CONCLUSION Through we successfully developed lead exhibiting activity, no harm honeybees. Further herbicides this is warranted. © 2025 Society Chemical Industry.

Language: Английский

Citations

0

Exploring the phytotoxicity mechanisms of PET nanoplastics and 6:2 FTSA in water hyacinth under individual and combined exposure scenarios DOI
Zhiheng Li,

Zhangchao Yao,

Shuping Wang

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137675 - 137675

Published: Feb. 19, 2025

Language: Английский

Citations

0

Dealkylation metabolites of Atrazine: A previously Neglected Contributor to soybean phytotoxicity within atrazine residue DOI Creative Commons
Nan Wang,

Yabo Liang,

Wangjing Zhai

et al.

Environment International, Journal Year: 2025, Volume and Issue: 199, P. 109498 - 109498

Published: April 25, 2025

Language: Английский

Citations

0

The phototoxicity of sulfamethoxazole stress on pakchoi cabbage (Brassica rapa var. chinensis) seedlings: From the perspective of photoreaction and omics analysis DOI

L. Shen,

Liangyu Zhang,

Jiaojun Jin

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 950, P. 175391 - 175391

Published: Aug. 8, 2024

Language: Английский

Citations

1

Effective periodate activation of direct Z-scheme g-C3N4/Cu2O heterojunction for photocatalytic norfloxacin degradation, anti-bacterial activity and toxicity assessment DOI
Qinyi Gu, Jian Rong, Yuzhe Zhang

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 159143 - 159143

Published: Dec. 1, 2024

Language: Английский

Citations

1

Response of Ceratophyllum demersum L. and its epiphytic biofilms to 6PPD and 6PPD-Q exposure: Based on metabolomics and microbial community analysis DOI
Xiang Li, Weitao Liu,

Yichen Ge

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 480, P. 136420 - 136420

Published: Nov. 5, 2024

Language: Английский

Citations

1

Variable cyanobacterial death modes caused by ciprofloxacin in the aquatic environment: Prioritizing antibiotic-photosynthetic protein interactions for risk assessment DOI
Yinjie Zhu,

Shishi Yao,

Xiaoxiong Wang

et al.

Water Research, Journal Year: 2024, Volume and Issue: 271, P. 122885 - 122885

Published: Nov. 29, 2024

Language: Английский

Citations

1