Breaking the mold: 3D cell cultures reshaping the future of cancer research DOI Creative Commons
Sandra Cordeiro, Beatriz B P P Oliveira, Rúben Valente

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 26, 2024

Despite extensive efforts to unravel tumor behavior and develop anticancer therapies, most treatments fail when advanced clinical trials. The main challenge in cancer research has been the absence of predictive models, accurately mimicking tumoral processes response treatments. microenvironment (TME) shows several human-specific physical chemical properties, which cannot be fully recapitulated by conventional 2D cell cultures or

Language: Английский

Breaking the mold: 3D cell cultures reshaping the future of cancer research DOI Creative Commons
Sandra Cordeiro, Beatriz B P P Oliveira, Rúben Valente

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 26, 2024

Despite extensive efforts to unravel tumor behavior and develop anticancer therapies, most treatments fail when advanced clinical trials. The main challenge in cancer research has been the absence of predictive models, accurately mimicking tumoral processes response treatments. microenvironment (TME) shows several human-specific physical chemical properties, which cannot be fully recapitulated by conventional 2D cell cultures or

Language: Английский

Citations

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