Effect of per- and polyfluoroalkyl substances on neurodevelopment: Evidence-based risk assessment in the TRAEC strategy context DOI Creative Commons
Jie Ning,

Chaoshun Ding,

Haoyi Xu

et al.

Environment International, Journal Year: 2024, Volume and Issue: unknown, P. 109003 - 109003

Published: Sept. 1, 2024

Although emerging evidence on the association between per- and polyfluoroalkyl substances (PFASs) neurodevelopment have been investigated, there is no consensus effect of maternal PFASs in offspring. Here, we assessed risk exposure offspring using a novel Targeted Risk Assessment Environmental Chemicals (TRAEC) strategy based multiple evidence. The from five online databases were analyzed neurodevelopment. potential was evaluated by TRAEC strategy, which conducted comprehensive scoring system with reliability, correlation, outcome fitness integrity. studies additional researchers' experiments included present study to proceed following assessment. Based framework evaluation health risks classified as low (absolute value 0-4), medium 4-8), high 8-10). In study, medium-risk level 5.61 overall risk-score. population-attributable (PAR) 8.26 % for exposure. identified low-risk prenatal ASD behavioral disabilities. chain length, type neurodevelopmental trajectories contributed Consistent results four criteria-based tools (ToxRTool, SciRAP, OHAT IRIS), assessment demonstrated robustness reliability study. These illustrated disorders addition, provided scientific structured method disorders, promoting consistency validation

Language: Английский

Per- and polyfluorinated substances in reservoir water from a metropolitan city in the Guangdong-Hong Kong-Macao Greater Bay Area, China, and their ecological risks DOI Creative Commons

Yiming Ge,

Yi Huang,

Linshen Xie

et al.

Environmental Chemistry and Ecotoxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

New Sources of Very Persistent and Very Mobile (vPvM) Substances: A Case Study of the Fluorinated Herbicide Pyroxasulfone DOI
Xingwang Hou, Jeremy R. Gauthier, Pranav Nair

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

With the increasing use of fluorinated agrochemicals, more compounds enter into environment. Pyroxasulfone (PYS), a broad-spectrum herbicide containing an aromatic CF3 (Ar-CF3), is expected to grow significantly in application. Although several transformation products (TPs) PYS have been reported, their distribution and contribution processes remain largely unknown. This study combined laboratory simulations field study. In soil incubation surface photolysis experiments, (5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanesulfonic acid (TFPSA) was identified as main TP soil, accounting for over 90% all TPs. Field results showed that TFPSA were species (6.48 ± 1.82 1.54 0.90 ng g-1 wet weight) corn plants (2.55 2.61 31.1 39.6 dry weight roots) before harvest. Surface water experiments TP246 major TPs no significant photodegradation observed. Persistent (P) mobile (M) property assessment indicated TFPSA, TP246, other Ar-CF3 various agrochemicals could be potential very P M (vPvM) substances. More attention should paid

Language: Английский

Citations

0

Effect of per- and polyfluoroalkyl substances on neurodevelopment: Evidence-based risk assessment in the TRAEC strategy context DOI Creative Commons
Jie Ning,

Chaoshun Ding,

Haoyi Xu

et al.

Environment International, Journal Year: 2024, Volume and Issue: unknown, P. 109003 - 109003

Published: Sept. 1, 2024

Although emerging evidence on the association between per- and polyfluoroalkyl substances (PFASs) neurodevelopment have been investigated, there is no consensus effect of maternal PFASs in offspring. Here, we assessed risk exposure offspring using a novel Targeted Risk Assessment Environmental Chemicals (TRAEC) strategy based multiple evidence. The from five online databases were analyzed neurodevelopment. potential was evaluated by TRAEC strategy, which conducted comprehensive scoring system with reliability, correlation, outcome fitness integrity. studies additional researchers' experiments included present study to proceed following assessment. Based framework evaluation health risks classified as low (absolute value 0-4), medium 4-8), high 8-10). In study, medium-risk level 5.61 overall risk-score. population-attributable (PAR) 8.26 % for exposure. identified low-risk prenatal ASD behavioral disabilities. chain length, type neurodevelopmental trajectories contributed Consistent results four criteria-based tools (ToxRTool, SciRAP, OHAT IRIS), assessment demonstrated robustness reliability study. These illustrated disorders addition, provided scientific structured method disorders, promoting consistency validation

Language: Английский

Citations

1