Wastewater-based surveillance of respiratory viruses in Northern Tuscany (Italy): Challenges and added value for public health purposes DOI Creative Commons
Annalaura Carducci, Ileana Federigi, Alessandra Almeida Castro Pagani

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177752 - 177752

Published: Nov. 30, 2024

During the COVID-19 pandemic, wastewater-based surveillance (WBS) showed great potential as an early warning system and could complement human clinical surveillance. This study aimed to highlight added value of WBS for respiratory infections alongside different systems. Sewage collected at entry four Wastewater Treatment Plants in Northern Tuscany (Italy) were analyzed SARS-CoV-2, Human Adenovirus (HAdV), Respiratory Syncytial Virus (RSV) Influenza (IV), over two years. Clinical data available area, while other viruses came from national virological For correlation was highly significant between hospitalization (ρ = 0.8460), but not wastewater or 0.1682 ρ 0.0569, respectively). SARS-CoV-2 RNA found even period when cases reported, indicating a continuous community circulation. HAdVs detected 74.3 % samples, most sequences identified belonged enteric species (HAdV-F41), need distinguishing causing diseases RSV only winter 2022-2023, IV had been wastewater, probably due poor test sensitivity. In conclusion, although there may be various challenges testing targets, can provide pathogen-specific situational assessment which complements existing

Language: Английский

Wastewater-based surveillance of respiratory viruses in Northern Tuscany (Italy): Challenges and added value for public health purposes DOI Creative Commons
Annalaura Carducci, Ileana Federigi, Alessandra Almeida Castro Pagani

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177752 - 177752

Published: Nov. 30, 2024

During the COVID-19 pandemic, wastewater-based surveillance (WBS) showed great potential as an early warning system and could complement human clinical surveillance. This study aimed to highlight added value of WBS for respiratory infections alongside different systems. Sewage collected at entry four Wastewater Treatment Plants in Northern Tuscany (Italy) were analyzed SARS-CoV-2, Human Adenovirus (HAdV), Respiratory Syncytial Virus (RSV) Influenza (IV), over two years. Clinical data available area, while other viruses came from national virological For correlation was highly significant between hospitalization (ρ = 0.8460), but not wastewater or 0.1682 ρ 0.0569, respectively). SARS-CoV-2 RNA found even period when cases reported, indicating a continuous community circulation. HAdVs detected 74.3 % samples, most sequences identified belonged enteric species (HAdV-F41), need distinguishing causing diseases RSV only winter 2022-2023, IV had been wastewater, probably due poor test sensitivity. In conclusion, although there may be various challenges testing targets, can provide pathogen-specific situational assessment which complements existing

Language: Английский

Citations

0