A Critical Review of Populations with Occupational Exposure to Per- and Polyfluoroalkyl Substances: External Exposome, Internal Exposure Levels, and Health Effects DOI

Anen He,

Yong Liang,

Juan Li

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: May 29, 2025

The relationship between per- and polyfluoroalkyl substances (PFAS) exposure human health has received widespread attention. This review focuses on the key distinctions in PFAS occupational population general from different countries. A systematic summary is made external environment, pathways, internal levels, effects of population. manufacturing, use, disposal processes increase their concentration levels ambient leading to significantly higher concentrations than background areas. Different pathways may lead molecular initiating events outcomes Moreover, are nearly one hundred times those Mixed more unknown another important feature Although not associated with mortality, can disrupt metabolic cause adverse liver, kidney, lipid homeostasis. Therefore, stringent protections for necessary reduce risks.

Language: Английский

A Critical Review of Populations with Occupational Exposure to Per- and Polyfluoroalkyl Substances: External Exposome, Internal Exposure Levels, and Health Effects DOI

Anen He,

Yong Liang,

Juan Li

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: May 29, 2025

The relationship between per- and polyfluoroalkyl substances (PFAS) exposure human health has received widespread attention. This review focuses on the key distinctions in PFAS occupational population general from different countries. A systematic summary is made external environment, pathways, internal levels, effects of population. manufacturing, use, disposal processes increase their concentration levels ambient leading to significantly higher concentrations than background areas. Different pathways may lead molecular initiating events outcomes Moreover, are nearly one hundred times those Mixed more unknown another important feature Although not associated with mortality, can disrupt metabolic cause adverse liver, kidney, lipid homeostasis. Therefore, stringent protections for necessary reduce risks.

Language: Английский

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