Langmuir,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
Block
copolymer
micelles
have
been
increasingly
used
for
the
solubilization
and
delivery
of
hydrophobic
drugs.
There
exists
a
possibility
dissociation
formation
other
association
structures
in
contact
with
gastrointestinal
fluid.
In
this
study,
we
demonstrated
effect
fed-state
intestinal
fluid
(FeSSIF)
upon
characteristics
bare
quercetin
(QCT)-loaded
pluronic
123
(P123)
micelles.
Characterizations
were
performed
using
dynamic
light
scattering
(DLS),
Tenside Surfactants Detergents,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 17, 2025
Abstract
This
study
investigates
the
effects
of
10
%
v/v
dimethyl
sulfoxide
(DMSO),
acetonitrile
(ACN),
and
1-propanol
(1-PrOH)
on
micellar
surface
behavior
three
ionic
surfactants:
sodiumdodecyl
sulfate
(SDS),
dodecyltrimethylammonium
bromide
(DTAB),
cetylpyridinium
chloride
(CPC).
The
addition
co-solvents
increased
critical
micelle
concentration
(CMC),
with
1-PrOH
causing
largest
increase
due
to
its
strong
disruption
hydrogen
bonding
network
water.
Surface
tension
measurements
revealed
a
decreased
excess
(
Γ
max
)
indicating
reduced
adsorption.
minimum
area
per
molecule
A
min
organic
solvents,
particularly
in
1-PrOH-water
mixtures,
reflecting
less
efficient
packing
surfactant
molecules
at
surface.
parameter
P
mixed
especially
1-PrOH,
suggesting
shift
from
spherical
elongated
structures.
Aggregation
numbers
N
agg
were
lower
solvent
systems,
smaller
stable
micelles.
free
energy
adsorption
∆Gadso
${\increment}{G}_{ads}^{o}$
became
negative,
spontaneity
for
formation
adsorption,
strongest
impact
seen
1-PrOH.
overall
trend
was
>
ACN
DMSO,
highlighting
role
polarity
amphiphilicity
altering
behavior.
These
results
provide
valuable
insights
optimization
surfactant-based
formulations.
Royal Society Open Science,
Journal Year:
2025,
Volume and Issue:
12(2)
Published: Feb. 1, 2025
Micellization
behaviour,
thermodynamics
and
dye-surfactant
interactions
are
the
main
topics
of
this
investigation
into
relationship
between
Remalan
Brilliant
Blue
R
(RBBR)
dye
n-alkyltrimethylammonium
chloride
(C
n
TAC;
=
12,
14,
16
18)
surfactants.
Conductometric
analysis
revealed
that
critical
micelle
concentration
decreased
with
increasing
alkyl
chain
length,
suggesting
longer
chains
formed
better
micelles.
Due
to
electrostatic
interactions,
spectrophotometric
analyses
notable
alterations
in
RBBR
absorption
following
contact
C
TAC.
Benesi-Hildebrand
Scott
equations
were
used
compute
binding
constant
(K
b),
which
increased
indicating
stronger
dye-micelle
interactions.
The
spontaneous
micelles
confirmed
by
thermodynamic
analysis,
showed
negative
Gibbs
free
energy
values
(ΔG).
stability
complexes
is
attributed
hydrophobic
forces,
as
seen
greater
ΔG
was
produced
chains.
Interestingly,
surfactant
concentrations
changed
equilibrium
adsorption
breaking
up
pre-formed
RBBR-C
TAC
complexes.
These
results
highlight
how
important
length
for
formation,
parameters
As
grew,
sequence
strength
found
be
C12TAC
<
C14TAC
C16TAC
C18TAC.
Langmuir,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 6, 2025
N-Acyl
amino
acids
are
biodegradable
anionic
amphiphilic
molecules
made
up
of
linear
fatty
as
hydrophobic
tails
and
polar
heads,
which
promising
for
their
applicability
in
different
technological
fields.
In
the
light
widening
use,
a
deeper
understanding
interactions
with
biological
membranes
is
required,
especially
to
further
assess
toxicological
profile.
We
investigated
interaction
between
N-decanoyl
acid
surfactants
phospholipid
bilayers
simple
vitro
models
comparison
sodium
dodecyl
sulfate
using
neutron
scattering
techniques.
The
information
from
small
angle
(SANS,
q
range
0.008
0.25
Å-1)
focusing
on
liposome-to-surfactant
reflectivity
(NR,
Q
measured
at
three
incident
angles
θ
=
0.35,
0.65,
1.5°)
lipid
bilayer-to-surfactant
was
combined
provide
detailed
characterization.
All
(C10-alanine,
C10-glycine,
C10-leucine,
C10-methionine,
C10-serine,
C10-proline)
exhibited
similar
behavior
terms
incorporation
liposomes
removal
well
adsorption
profiles
critical
micelle
concentration
(CMC).
Notably,
bilayer
destabilization
occurred
all
(except
C10-serine
C10-alanine)
CMC
2×
CMC.
Such
result
demonstrates
exceptional
ability
C10-alanine
integrate
into
without
disruption
concentrations
high
∼3-4×
These
findings
support
lower
cytotoxic
effect
surfactants,
observed
previous
studies,
new
insights
mechanism
membranes.
Tenside Surfactants Detergents,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 8, 2025
Abstract
The
oxidation
of
amino
acids
is
interesting
due
to
the
different
molecules
generated
by
oxidants.
This
research
crucial
understand
role
in
redox
processes
and
identify
active
species
Ru(III)
diperiodatocuprate(III)
(DPC).
purpose
present
analyze
effect
cationic
surfactant
on
catalysed
l
-tyrosine
(
-Tyr)
DPC.
progression
reaction
was
evaluated
using
pseudo-first-order
scenario
as
a
metric
for
[OH
−
],
[DPC],
ionic
strength,
[
-Tyr],
[Ru(III)],
[IO
4
[surfactant],
temperature.
Over
range
concentrations
studied,
observed
exhibits
kinetic
order
less
than
one
with
respect
both
]
negative
fractional
first-order
dependence
[Ru(III)]
[DPC].
constancy
rate
electrolyte
addition
suggests
zero
salt
effect.
markedly
increased
solution
acting
catalyst
at
ppm
concentration.
micellar
media
cetylpyridinium
chloride
(CPC)
significantly
accelerates
desired
reaction,
achieving
fourfold
increase.
compatibility
CPC
-Tyr
DPC
particularly
noteworthy.
