Molecules,
Journal Year:
2019,
Volume and Issue:
24(2), P. 334 - 334
Published: Jan. 18, 2019
The
reliable
and
efficient
production
of
radioisotopes
for
diagnosis
therapy
is
becoming
an
increasingly
important
capability,
due
to
their
demonstrated
utility
in
Nuclear
Medicine
applications.
Starting
from
the
first
processes
involving
separation
99mTc
irradiated
materials,
several
methods
concepts
have
been
developed
selectively
extract
interest.
Even
though
initial
were
based
on
liquid-liquid
extraction
(LLE)
approaches,
perceived
difficulty
automating
such
has
slowly
moved
focus
towards
resin
methods,
whose
basic
chemical
principles
are
often
similar
LLE
ones
terms
chelators
phases.
However,
emerging
field
flow
chemistry
allows
be
easily
automated
operated
a
continuous
manner,
resulting
even
improved
efficiency
reliability.
In
this
contribution,
we
will
outline
fundamentals
translation
into
flow-based
apparatuses;
addition,
provide
examples
radioisotope
separations
that
achieved
using
methods.
This
article
intended
offer
insights
about
future
potential
purify
medically
relevant
radioisotopes.
Journal of Separation Science,
Journal Year:
2019,
Volume and Issue:
43(1), P. 202 - 225
Published: Nov. 6, 2019
Advances
in
the
area
of
sample
preparation
are
significant
and
have
been
growing
significantly
recent
years.
This
initial
step
analysis
is
essential
must
be
carried
out
properly,
consisting
a
complicated
procedure
with
multiple
stages.
Consequently,
it
corresponds
to
potential
source
errors
will
determine,
at
end
process,
either
satisfactory
result
or
fail.
One
advances
this
field
includes
miniaturization
extraction
techniques
based
on
conventional
procedures
such
as
liquid-liquid
solid-phase
extraction.
These
modern
gained
prominence
face
traditional
methods
since
they
minimize
consumption
organic
solvents
volume.
As
another
feature,
possible
reuse
sorbents,
its
coupling
chromatographic
systems
might
automated.
The
review
emphasize
main
liquid-phase
microextraction,
well
those
upon
use
sorbents.
first
group
currently
popular
single
drop
hollow
fiber
dispersive
microextraction.
In
second
group,
microextraction
in-tube
stir
bar
sorptive
extraction,
micro
by
packed
sorbent
highlighted.
approaches,
common,
aim
determination
analytes
low
concentrations
complex
matrices.
article
describes
some
characteristics,
advances,
trends
miniaturized
techniques,
their
current
applications
food,
environmental,
bioanalysis
fields.
Advanced Materials Interfaces,
Journal Year:
2023,
Volume and Issue:
11(2)
Published: Oct. 27, 2023
Abstract
Separation
and
identification
of
molecules
biomolecules
such
as
nucleic
acids,
proteins,
polysaccharides
from
complex
fluids
are
known
to
be
important
due
unmet
needs
in
various
applications.
Generally,
many
different
separation
techniques,
including
chromatography,
electrophoresis,
magnetophoresis,
have
been
developed
identify
the
target
precisely.
However,
these
techniques
expensive
time
consuming.
“Lab‐on‐a‐chip”
systems
with
low
cost
per
device,
quick
analysis
capabilities,
minimal
sample
consumption
seem
ideal
candidates
for
separating
particles,
cells,
blood
samples,
molecules.
From
this
perspective,
microfluidic‐based
extensively
past
two
decades
separate
samples
origins.
In
review,
“lab‐on‐a‐chip”
methods
by
passive,
active,
hybrid
approaches
decade
comprehensively
discussed.
Due
wide
variety
field,
it
will
impossible
cover
every
facet
subject.
Therefore,
review
paper
covers
passive
active
generally
used
biomolecule
separation.
Then,
an
investigation
combined
sophisticated
is
highlighted.
The
spotlight
also
shined
on
elegance
successes
recent
years,
remainder
article
explores
how
permit
development
novel
techniques.
Critical Reviews in Environmental Science and Technology,
Journal Year:
2018,
Volume and Issue:
49(1), P. 1 - 31
Published: Dec. 3, 2018
Highly
radioactive
and
hazardous
radionuclides
in
nuclear-spent
fuel
are
harmful
to
the
environment
hinder
further
development
of
nuclear
energy
industry.
Microextractors,
with
advantages
a
small
volume,
fast
extraction
kinetics,
passive
operation
mode,
ability
integrate
detection
instruments,
considered
perfect
candidates
for
mitigation
risks
related
spent
reprocessing.
The
applications
microextractors
reprocessing
can
be
classified
into
two
groups.
first
one
includes
micro/mini
plants,
other
encompasses
radiochemical
analysis.
This
review
introduces
both
groups
detail,
including
their
basic
concepts,
principles,
research
status.
