Doping Detection Based on the Nanoscale: Biosensing Mechanisms and Applications of Two-Dimensional Materials

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 227 - 227

Published: April 3, 2025

Doping undermines fairness in sports and threatens athlete health, while conventional detection methods like LC-MS GC-MS face challenges such as complex procedures, matrix interferences, lengthy processing times, limiting on-site applications. Two-dimensional (2D) materials, including graphene, MoS2, metal–organic frameworks (MOFs), offer promising solutions due to their large surface areas, tunable electronic structures, special interactions with doping agents, hydrogen bonding, π-π stacking, electrostatic forces. These materials enable signal transduction through changes conductivity or fluorescence quenching. This review highlights the use of 2D detection. For example, reduced graphene oxide–MOF composites show high sensitivity for detecting anabolic steroids testosterone, NiO/NGO nanocomposites exhibit strong selectivity stimulants ephedrine. However, environmental instability production costs hinder widespread application. Future efforts should focus on improving material stability chemical modifications, reducing costs, integrating these into advanced systems machine learning. Such advancements could revolutionize detection, ensuring protecting health.

Language: Английский

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Segregation of Constitutional Isomers of Some Aromatic Amines Exploiting the Changes of Photo‐Luminescence Behaviour of Isoreticular Metal‐Organic Frameworks

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Abstract Three different two dimensional Cd(II)‐based metal−organic frameworks (MOFs) have been synthesized by utilizing same N,N′‐donor ligand and three functionalized dicarboxylate linkers namely isophthalate, 5‐nitroisophthalate 5‐hydroxyisophthalate for compound 1 , 2 3 respectively. The compounds that are isoreticular bi‐walled 2D frameworks, show dual fluorescence emission spectra their π‐π* n‐π* excitation. Compound is consists of unsubstituted bridging isophthalate whereas made with substituted electron withdrawing –NO group donating –OH These electronic environments in MOFs found effective to respond differently towards the constitutional isomers aromatic amines having suitable environment. responses non‐polar –CH containing picolylamine moieties, showing maximum enhancement 2‐picolylamine comparison 3‐ 4‐ isomer derivates. consisting group, more significantly rich phenylenediamines quenching case m‐phenylenediamine compared ortho para isomers. change functionalisation from helps detect deficient aminopyridines; where has observed presence 3‐aminopyridine contrast its other

Language: Английский

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Two-Dimensional Cu-Based MOF for Selective Staining of the Cellular Nucleus through Fluorescence Imaging and Selective Sorption of Dye Molecules in Aqueous Medium

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 63(29), P. 13439 - 13449

Published: July 9, 2024

A two-dimensional copper-based metal-organic framework, [Cu(C

Language: Английский

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Regulating electrical conductivity and Schottky nature of d10 metal ion based nanoarchitectonics of coordination polymers

CrystEngComm, Journal Year: 2024, Volume and Issue: 26(46), P. 6618 - 6626

Published: Jan. 1, 2024

This study emphasizes the impact of a d 10 metal ion [Cd( ii )/Zn( )] on charge transportation and Schottky barrier diode behavior coordination polymers based highly conjugated ligand 4-(1-naphthylvinyl)pyridine.

Language: Английский

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