Rapid synthesis of CuTA/Cur@ZIF-8 multifunctional drug delivery system towards cancer treatment

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136321 - 136321

Published: Feb. 1, 2025

Language: Английский

Cu(II) Metal–Organic Framework as a Recyclable Heterogeneous Catalyst for Substituted Pyridine Synthesis from Cyclic Ketones with Propargylamine

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

The creation of efficient and stable metal-organic framework (MOF) catalysts with coordinatively unsaturated metal sites is critical in modern organic synthesis. Herein, we reported one new Cu(II)-MOF the chemical formula {[Cu(L)(H2O)]·2DMA·H2O}∞ (1) (H2L = 4,4'-((4R,5R)-4,5-diphenylimidazolidine-1,3-diyl)dibenzoic acid) for annulation cyclic ketones propargylamine. Compound 1 possesses a 2-fold interpenetrating 3D kagome net channel opening about 20 Å diameter. Framework 1' exhibits high permanent porosity (778 m2/g, BET) recyclable catalytic activity propargylamine one-pot tandem reaction, affording series substituted pyridines good yield. X-ray photoelectron spectroscopy analysis indicates that Cu(II) reduced to active Cu(I) species reaction system, while selectively activate triple bond promote annulation. successful preparation heterogeneous presents opportunities developing highly Cu or other transformations mediated by Cu.

Language: Английский

Development of a Self-Driven Electron Transfer Metal-Organic Framework for Reactive Oxygen Species (ROS) Generation in Gsh-Depleted Cancer Therapy

Published: Jan. 1, 2025

Language: Английский