Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies DOI Creative Commons
Fan Xu, Yao Liu, Zujun Que

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Metastasis is the leading cause of death in patients with lung cancer. Multidisciplinary comprehensive treatments (MDT), including surgery, chemotherapy, radiotherapy, gene-targeted therapy, immunotherapy, antibody-drug conjugate (ADC), natural products, etc., have been currently used for cancer metastasis. The MDT model has shown promising efficacy against metastasis clinical practice. However, these therapies some limitations, such as unusual toxic side effects, drug resistance, limited indications, and high costs. Therefore, emerging technological platforms are imperative to overcome bottlenecks. Nanomedicine can be prepare efficient delivery systems owing its good biocompatibility, targeting, responsive release, multidrug codelivery plays an important role synergistic antimetastasis because optical, acoustic, electrical, thermal, magnetic functions. This review analyses limitations model, briefly outlines advantages nanotechnology, introduces nanodrug systems, summarizes nanostrategies based on invasion-metastasis cascade process, provides a summary prospects challenges translation nanomedicines.

Language: Английский

Unveiling the Racemization in Ferroelectrics with Coupled Ferroelectricity and Optical Activity DOI
Xiang‐Bin Han, Chengdong Liu,

Chang‐Qing Jing

et al.

The Journal of Physical Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown, P. 642 - 649

Published: Jan. 9, 2025

The most distinctive features of ferroelectrics are spontaneous polarization and depolarization. Ferroelectricity was first observed in Rochelle salt, a compound with chiral component which the molecular chirality is not affected by For structurally (SCFs), such as triglycine sulfate, lacks components, depolarization effect on presents an intriguing unexplored topic. In this study, we focus newly proposed optical topic optically active coupled ferroelectricity activity. We examined activity these ferroelectric materials employed chiral-environment crystallization solid-state circular dichroism (CD) techniques to elucidate racemization-depolarization mechanism SCF for time. polar nonchiral ferroelectrics, averaged out powder state, resulting no CD signal. Additionally, experimentally validated consistency between measurements theory across four point groups (m, mm2, 4̅, 4̅2m). These findings could advance development spintronic devices leveraging tune spin selectivity.

Language: Английский

Citations

0
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies DOI Creative Commons
Fan Xu, Yao Liu, Zujun Que

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Metastasis is the leading cause of death in patients with lung cancer. Multidisciplinary comprehensive treatments (MDT), including surgery, chemotherapy, radiotherapy, gene-targeted therapy, immunotherapy, antibody-drug conjugate (ADC), natural products, etc., have been currently used for cancer metastasis. The MDT model has shown promising efficacy against metastasis clinical practice. However, these therapies some limitations, such as unusual toxic side effects, drug resistance, limited indications, and high costs. Therefore, emerging technological platforms are imperative to overcome bottlenecks. Nanomedicine can be prepare efficient delivery systems owing its good biocompatibility, targeting, responsive release, multidrug codelivery plays an important role synergistic antimetastasis because optical, acoustic, electrical, thermal, magnetic functions. This review analyses limitations model, briefly outlines advantages nanotechnology, introduces nanodrug systems, summarizes nanostrategies based on invasion-metastasis cascade process, provides a summary prospects challenges translation nanomedicines.

Language: Английский

Citations

0