Current Microwave Chemistry,
Journal Year:
2023,
Volume and Issue:
10(2), P. 180 - 197
Published: Sept. 1, 2023
Abstract:
Microwave-assisted
synthesis
is
a
powerful
tool
in
organic
chemistry,
providing
rapid
and
efficient
method
for
the
of
bioactive
heterocycles.
The
application
micro-waves
significantly
reduces
reaction
times
increases
percentage
yields
with
high
purity
final
product.
To
make
synthetic
protocol
greener,
magnetic
nanocata-lyst
rapidly
growing
area
interest
nowadays.
Magnetic
nanocatalyst,
its
unique
fea-tures
like
separable
facile
recovery
from
media
heterogeneously,
makes
overall
strategy
cleaner,
faster,
cost-effective.
Aiming
this,
present
review,
we
will
focus
on
infusion
nanocatalyst
to
microwave-assisted
vari-ous
classes
azaheterocyclic
compounds,
including
pyridines,
pyrimidines,
quinolines,
ben-zimidazoles.
methodologies
involved
preparation
these
heterocycles
are
highlighted,
along
their
biological
activities.
Furthermore,
this
most
recent
advanced
strategies
incorporate
nanocatalysts
nat-ural
products
containing
moieties
drug
discovery
programs
elucidated
detail,
incoming
future
scope
challenges.
Langmuir,
Journal Year:
2023,
Volume and Issue:
39(26), P. 9069 - 9077
Published: June 26, 2023
A
Dioscorea
opposita
Thunb
polysaccharide
(DOP)-modified
ZIF8
material
was
developed
in
this
study,
which
can
be
used
as
a
"smart"
glucose-responsive
carrier
to
control
the
slow
release
of
drugs.
The
3-aminophenylboronic
acid
(APBA)
functionalized
carboxylated
long-chain
polymer
poly(ethylene
glycol)
(PEG)
segments,
were
first
modified
on
surface
nanoparticles
with
hydrogen
bond
and
then
chemically
cross-linked
DOP
through
borate
ester
bond,
leading
drugs
loaded
being
"closed"
PBS
but
"open"
via
taking
off
coating
high
concentrations
glucose;
thus,
leakage
prevented
drug
glucose-triggered
effectively
result.
Moreover,
materials
showed
good
biocompatibility
released
trans-N-p-coumaroyltyramine
(NCT)
could
work
synergistically
improve
insulin
resistance
promote
glucose
consumption
insulin-resistant
HepG2
cells.
Journal of Fungi,
Journal Year:
2024,
Volume and Issue:
10(8), P. 519 - 519
Published: July 25, 2024
Difenoconazole-loaded
(CS-DIF)
microcapsules
were
synthesized
by
encapsulating
difenoconazole
into
biocompatible
chitosan.
The
physical
and
chemical
properties
indicated
that
the
encapsulation
loading
rates
85.58%
61.98%,
respectively.
exhibited
prominent
controlled-release
surface
stability
performance.
cumulative
release
rate
was
only
33.6%
in
168
h,
contact
angle
decreased
11.73°
at
120
s
compared
with
difenoconazole.
antifungal
activity
of
CS-DIF
against
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 23, 2024
Abstract
Thymelaceaous
trees
are
prized
for
accumulating
fragrant
resins
composed
of
hundreds
secondary
metabolites
in
their
woody
tissues.
Slow
growth
and
increasing
consumer
demand
have
stretched
natural
sources
agarwood
to
being
endangered
alternative
production
modes,
including
silviculture
tissue
culture,
currently
investigated.
Dedifferentiated
culture
provides
a
means
cell
propagation
independent
environmental
context.
However,
metabolite
accumulation,
as
found
resins,
occurs
largely
response
wounding.
Here,
we
investigated
the
application
metal-organic
frameworks
(MOFs)
potential
elicitors
formation
Aquilaria
crassna
samples.
Callus
cultures
were
exposed
five
commercially
available
MOFs:
UiO-67,
MOF-808,
HKUST-1,
ZIF-67,
MOF-74,
ethanol
extracts
used
quantify
accumulation
compared
untreated
cultures.
Samples
that
Zr-based
MOFs
exhibited
similar
profiles,
(trans-2-Carboxy-cyclo-hexyl)-acetic
acid
was
reduced
presence
all
MOFs,
Cu-containing
HKUST-1
MOF
increased
palmitic
levels,
MOF-808
ZIF-67
elicit
highest
with
fragrance
applications.
These
results
demonstrate
possibility
eliciting
from
dedifferentiated
tree
may
provide
an
sourcing
specialty
chemicals
these
plants.
Current Microwave Chemistry,
Journal Year:
2023,
Volume and Issue:
10(2), P. 180 - 197
Published: Sept. 1, 2023
Abstract:
Microwave-assisted
synthesis
is
a
powerful
tool
in
organic
chemistry,
providing
rapid
and
efficient
method
for
the
of
bioactive
heterocycles.
The
application
micro-waves
significantly
reduces
reaction
times
increases
percentage
yields
with
high
purity
final
product.
To
make
synthetic
protocol
greener,
magnetic
nanocata-lyst
rapidly
growing
area
interest
nowadays.
Magnetic
nanocatalyst,
its
unique
fea-tures
like
separable
facile
recovery
from
media
heterogeneously,
makes
overall
strategy
cleaner,
faster,
cost-effective.
Aiming
this,
present
review,
we
will
focus
on
infusion
nanocatalyst
to
microwave-assisted
vari-ous
classes
azaheterocyclic
compounds,
including
pyridines,
pyrimidines,
quinolines,
ben-zimidazoles.
methodologies
involved
preparation
these
heterocycles
are
highlighted,
along
their
biological
activities.
Furthermore,
this
most
recent
advanced
strategies
incorporate
nanocatalysts
nat-ural
products
containing
moieties
drug
discovery
programs
elucidated
detail,
incoming
future
scope
challenges.
