Differential characteristics of chemical composition, fermentation metabolites and antioxidant effects of polysaccharides from Eurotium Cristatum and Fu-brick tea

Food Chemistry, Journal Year: 2024, Volume and Issue: 461, P. 140934 - 140934

Published: Aug. 22, 2024

Language: Английский

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The dynamic of physicochemical properties, volatile compounds and microbial community during the fermentation of Chinese rice wine with diverse cereals

Food Research International, Journal Year: 2024, Volume and Issue: 198, P. 115319 - 115319

Published: Nov. 10, 2024

Language: Английский

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Artificial protein coronas: directing nanoparticles to targets

Trends in Pharmacological Sciences, Journal Year: 2024, Volume and Issue: 45(7), P. 602 - 613

Published: May 28, 2024

Language: Английский

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Enhancing bioavailability and functionality of plant peptides and proteins: A review of novel strategies for food and pharmaceutical applications

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144440 - 144440

Published: April 1, 2025

Language: Английский

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Towards Understanding Particle-Protein Complexes: Physicochemical, Structural, and Cellbiological Characterization of β-Lactoglobulin Interactions with Silica, Polylactic Acid, and Polyethylene Terephthalate Nanoparticles

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 253, P. 114702 - 114702

Published: April 22, 2025

Nanoplastic particles and their additives are increasingly present in the food chain, interacting with biomacromolecules not yet known consequences. A protein corona forms around these usually complex matrices, primarily a first contact at surface-active proteins. However, systematic studies on interactions between proteins -especially regarding affinity structural changes due to surface properties like polarity - limited. It is also unclear whether can "mask" particles, mimic properties, induce cytotoxic effects when internalized by mammalian cells. This study aimed investigating physicochemical of model particle-protein complexes, adsorbed proteins, Caco-2 Whey β-lactoglobulin (β-Lg) was used as well-characterized studied mixture nanoparticles varying polarity, specifically silica, polylactic acid (PLA), polyethylene terephthalate (PET). The analyses included measurements hydrodynamic diameter zeta potential, while conformational were analyzed using Fourier-transform-infrared spectroscopy (FTIR) intrinsic fluorescence. Cellular uptake cells assessed through flow cytometry, cell viability measured 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium-bromide (MTT) assay, cellular impedance xCELLigence® technology. results indicated that β-Lg had highest for hydrophilic silica forming silica-β-Lg complexes large aggregates electrostatic interactions. decreased PLA lowest hydrophobic PET, which formed smaller complexes. Adsorption onto caused partial unfolding refolding β-Lg. cells, impairing proliferation. In contrast, PLA- PET-protein internalized, though slightly reduced viability. enhances our understanding adsorption its potential biological effects.

Language: Английский

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Fabrication of glycosylated wheat gliadin hydrolysate nanoparticle for stabilization of quercetin: interaction characteristics, conformational changes and stability

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 144481 - 144481

Published: May 1, 2025

Language: Английский

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Toxicity of Engineered Nanoparticles in Food: Sources, Mechanisms, Contributing Factors, and Assessment Techniques

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 26, 2025

The increasing prevalence of engineered nanoparticles (ENPs) in food systems has raised concerns about their toxicity and potential health risks. To provide a comprehensive evaluation, structured literature search was conducted using databases such as Web Science PubMed, focusing on studies published the past ten years that examine ENP exposure pathways, mechanisms, contributing factors, risk assessment strategies. This review first explores diverse sources ENPs, including additives, nanocarriers, packaging, agricultural practices, environmental contamination. Upon ingestion, ENPs undergo complex transformations within human gastrointestinal tract (GIT), causing oxidative stress, cellular dysfunction, inflammation, gut microbiota dysbiosis, potentially leading to systemic vital organs. is influenced by physicochemical properties, matrix effects, GIT conditions, host-specific factors. further discusses current methodologies, silico, vitro, vivo, emerging technologies. Finally, we identify critical research gaps, lack long-term limited evaluations organic ENPs. By providing analysis ingested toxicity, this aims guide safer applications mitigate

Language: Английский

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Preparation of sodium alginate and chitosan modified curcumin liposomes and study on the formation of protein corona

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139392 - 139392

Published: Dec. 1, 2024

Language: Английский

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A glutenin protein corona ameliorated TiO₂ nanoparticle-induced gut barrier dysfunction and altered the gut microbiota composition

Food & Function, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The formation of glutenin protein corona alleviated gut microbiota dysbiosis, increased the short chain fatty acid production, improved barrier function, mitigated mitochondrial dysfunction, and reduced reactive oxygen species.

Language: Английский

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Tailored protein corona behavior in titanium dioxide nanosheet fluorescence biosensor for protein quantification assays

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 683, P. 106 - 115

Published: Dec. 22, 2024

Language: Английский

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