Biological Activities of Constituents from Rosa roxburghii and Their Mechanisms Based on Network Pharmacology and Biological Verification
Li-juan Xiang,
No information about this author
Shuang Zhang,
No information about this author
Mingliang Luo
No information about this author
et al.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(3), P. 1353 - 1353
Published: Feb. 5, 2025
Rosa
roxburghii
Tratt
is
widely
cultivated
in
southwestern
areas
of
China
for
a
range
purposes,
including
food
and
medicine.
To
enhance
its
application
value,
one
previously
undescribed
compound
(1)
six
known
compounds
(2-7)
were
isolated
from
the
roots
R.
roxburghii.
The
structures
(1-7)
determined
through
NMR,
HR-MS,
CD
experiments,
by
comparison
their
spectroscopic
data
with
values
literature.
Roxbubenzoate
A
contained
benzoyl
glucuronosyl
glycerol
scaffold
featuring
rare
α-glucuronosyl
linkage.
Seven
tested
anti-inflammatory,
α-glucosidase-inhibitory,
radical-scavenging
activities.
Compound
3
showed
significant
inhibitory
effect
on
release
NO
LPS-induced
RAW264.7
macrophages,
an
IC50
value
7.8
±
0.2
μM.
Compounds
2,
4,
7
exhibited
moderate
activity
against
α-glucosidase,
inhibition
rates
50.1%,
46.7%,
41.1%
at
concentration
200
μM,
respectively.
1,
6
ABTS
activity,
107.0
1.1,
142.6
0.8,
128.3
1.2
network
pharmacological
analysis
molecular
docking
results
suggested
that
may
be
able
to
treat
inflammation
binding
TNF-α
IL-6
targets.
Finally,
expression
macrophages
was
detected
ELISA,
strong
release.
These
findings
offer
novel
perspective
development
rich
medicinal
plant
resources
roots.
Language: Английский
Recent progress in chemistry and bioactivity of novel enzyme inhibitors from natural products: a comprehensive review
European Journal of Medicinal Chemistry,
Journal Year:
2025,
Volume and Issue:
289, P. 117481 - 117481
Published: March 7, 2025
Language: Английский
Mechanistic insights into the quality maintenance of postharvest Cili induced by stress from exogenous H2O2 through ‘Physio-Omic-CompBio’ tripartite correlation
Postharvest Biology and Technology,
Journal Year:
2025,
Volume and Issue:
228, P. 113631 - 113631
Published: May 16, 2025
Language: Английский
Dynamic Changes of Active Components and Volatile Organic Compounds in Rosa roxburghii Fruit during the Process of Maturity
Su Xu,
No information about this author
Junyi Deng,
No information about this author
Siyao Wu
No information about this author
et al.
Foods,
Journal Year:
2024,
Volume and Issue:
13(18), P. 2893 - 2893
Published: Sept. 12, 2024
),
native
to
the
southwest
provinces
of
China,
is
a
fruit
crop
important
economic
value
in
Guizhou
Province.
However,
changes
quality
and
flavor
during
Language: Английский
Effects of Different Drying Methods on Drying Kinetic Models, Physicochemical Properties, and Drying Quality Composite Scores of Rosa roxburghii Tratt (Fruit)
Wei Ren,
No information about this author
Jian Xu,
No information about this author
Yong-Ping Zhang
No information about this author
et al.
Journal of Food Biochemistry,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
The
aim
of
this
study
is
to
investigate
efficient,
cost‐effective,
and
high‐quality
drying
technologies
for
Rosa
roxburghii
Tratt.
Five
methods—hot
air
(HAD),
microwave
(MD),
vacuum
(VD),
(MVD),
freeze
(FVD),
were
employed
dry
focused
on
evaluating
characteristics,
colors,
texture
structure,
microstructure,
as
well
the
content
active
ingredients
antioxidant
activity
results
kinetics
indicated
that
Wang
Singh
model
was
most
suitable
FVD,
while
Page
optimal
other
four
methods.
Tratt
subjected
HAD
exhibited
highest
energy
consumption
per
unit
but
lowest
ΔE
TFC.
microstructure
under
different
methods
analyzed.
dried
using
MD
experienced
serious
cell
rupture,
resulting
in
a
large
loss
worst
ability,
it
had
fastest
rate.
On
hand,
VD
with
least
pore
space,
leading
slower
speed
total
polyphenol
content.
MVD
hardness
chewiness,
slightly
better
Δ
E
ingredient
compared
MD.
FVD
took
longest
time
dry,
greatest
difference,
hardness,
Vitamin
C
powerful
ability.
Principal
component
analysis
(PCA)–entropy
weighting
method
used
provide
comprehensive
scores
methods,
HAD,
VD,
MVD,
0.8107,
0.7037,
0.4499,
0.2746,
0.0586
respectively.
Through
analysis,
we
demonstrated
quality
obtained
via
satisfactory.
Additionally,
characterized
by
its
economic
efficiency
convenience,
providing
valuable
insights
industrial
production
drying.
Language: Английский
Unlocking Photosynthetic Potential: Harnessing Rosa roxburghii Derived Carbon Dots as Nanofertilizers for Enhanced Plant Growth
Qing-Yun Xu,
No information about this author
Jae Hee Han,
No information about this author
Dongyu Wang
No information about this author
et al.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 17, 2024
The
synthesis
of
nanomaterials
from
renewable
resources
has
emerged
as
an
environmentally
friendly
alternative.
This
approach
helps
to
reduce
the
use
chemical
fertilizers
in
agricultural
production,
further
reducing
potential
harm
ecosystem
and
effectively
burden
on
environment.
In
this
work,
we
synthesized
Language: Английский