Gold(I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR DOI
Yawen Wang, Xiaoyan Ma, Xuejie Chen

et al.

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 283, P. 117137 - 117137

Published: Dec. 4, 2024

Language: Английский

A dinuclear gold(I) complex with bis(N-heterocyclic carbene) ligands potentiated immune responses against liver cancer via ROS-driven endoplasmic reticulum stress and ferroptosis DOI

Qiuyue Lu,

Min Shan,

Jiaqi Yang

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110940 - 110940

Published: Feb. 1, 2025

Language: Английский

Citations

1
Anticancer Diiron Aminocarbyne Complexes with Labile N-Donor Ligands DOI
Sara Stocchetti, Ján Vančo, Giulio Bresciani

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 286, P. 117304 - 117304

Published: Jan. 21, 2025

Language: Английский

Citations

0
Tuning In Vitro Cytotoxicity in Diruthenium(I) bis‐Cyclopentadienyl Complexes DOI
Benedetta Bertoncini,

Kseniya Glinkina,

Stefano Zacchini

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(5)

Published: April 3, 2025

ABSTRACT A series of diruthenium(I) aminocarbyne complexes general formula [Ru 2 Cp (CO)(L)(μ‐CO){μ‐CNMe (Cy)}] + (L = NH 3 , [ ] ; Py, PPh 4 DMSO, 5 thiourea, 6 ) and (μ‐H)(CO) {μ‐CNMe (Cy)}], 7 were prepared from the tricarbonyl precursor (CO) (μ‐CO){μ‐CNMe . The reactivity vinyliminium complex (CO)(μ‐CO){μ‐η 1 :η ‐C (Ph)CHCNMe was also investigated, providing access to piano stool Ru (II) cyclopentadienyl with a five‐membered metallacyclic ligand containing sulfur. new compounds characterized by IR multinuclear NMR spectroscopy X‐ray diffraction (in three cases). solubility in water, lipophilicity, speciation – ]CF SO water/DMSO cell culture medium are regulated different monodentate ligands. Subsequently, tested vitro against human ovarian cancer cells (A2780 A2780cis) embryonic kidney (HEK293), demonstrating moderate potent cytotoxicity.

Language: Английский

Citations

0
Synthesis of N-heterocyclic carbene‑selenium complexes modulating apoptosis and autophagy in cancer cells: Probing the interactions with biomolecules and enzymes DOI
Rizwan Ashraf,

Zohra Khalid,

Qi‐Pin Qin

et al.

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: 160, P. 108435 - 108435

Published: April 5, 2025

Language: Английский

Citations

0
Metallodrugs: Synthesis, mechanism of action and nanoencapsulation for targeted chemotherapy DOI
Jéssica Andreza Oliveira Rodrigues,

Neelakanta Sarvashiva Kiran,

Ankita Chatterjee

et al.

Biochemical Pharmacology, Journal Year: 2024, Volume and Issue: 231, P. 116644 - 116644

Published: Nov. 20, 2024

Language: Английский

Citations

0
The Effect of a Varying Pyridine Ligand on the Anticancer Activity of Diiron(I) Bis-Cyclopentadienyl Complexes DOI Creative Commons

Annachiara Rossi,

Lorenzo Biancalana, Ján Vančo

et al.

Chemico-Biological Interactions, Journal Year: 2024, Volume and Issue: 406, P. 111318 - 111318

Published: Nov. 26, 2024

Language: Английский

Citations

0
Gold(I) complexes bearing EGFR-inhibiting ligands as anti-HCC agents through dual targeting of EGFR and TrxR DOI
Yawen Wang, Xiaoyan Ma, Xuejie Chen

et al.

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 283, P. 117137 - 117137

Published: Dec. 4, 2024

Language: Английский

Citations

0