SSRN Electronic Journal,
Journal Year:
2021,
Volume and Issue:
unknown
Published: Jan. 1, 2021
5-ethoxymethylfurfural
(EMF)
is
a
potential
biofuel
that
can
be
obtained
from
the
etherification
of
5-hydroxymethylfurfural.
In
this
work,
green
methodology
was
developed
to
produce
product
through
one-pot
tandem
reaction,
starting
directly
fructose,
eliminating
unnecessary
process
steps
and
isolation
intermediates.
For
this,
heating
by
microwave
irradiation
p-sulfonic
acid
calix[4]arene
(CX4SO3H)
as
organocatalyst
were
used.
EMF
in
88%
yield
mixture
ethanol,
fructose
CX4SO3H
(1.0
mol%)
at
140
°C
for
20
min.
addition,
we
highlight
other
advantages
methodology,
such
(i)
use
non-toxic
catalyst,
(ii)
short
reaction
time,
(iii)
efficient
system,
(iv)
metal-free
process,
(v)
formation
two
π
bonds
C-C
one
C-O
sequence,
(vi)
water
sole
waste
(vii)
according
chemistry.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(4), P. 1304 - 1304
Published: Feb. 15, 2022
Diels-Alder
cycloaddition
reaction
is
one
of
the
most
powerful
strategies
for
construction
six-membered
carbocyclic
and
heterocyclic
systems,
in
cases
with
high
regio-
stereoselectivity.
In
this
review,
an
insight
into
relevant
advances
on
sustainable
reactions
since
2010
provided.
Various
environmentally
benign
solvent
systems
are
discussed,
namely
bio-based
derived
solvents
(such
as
glycerol
gluconic
acid),
polyethylene
glycol,
deep
eutectic
solvents,
supercritical
carbon
dioxide,
water
water-based
aqueous
systems.
Issues
such
method's
scope,
efficiency,
selectivity
mechanism,
well
sustainability,
advantages
limitations
these
media,
addressed.
Synthesis,
Journal Year:
2022,
Volume and Issue:
54(14), P. 3162 - 3179
Published: March 10, 2022
Abstract
The
multicomponent
Povarov
reaction
represents
a
powerful
approach
for
the
construction
of
substances
containing
N-heterocyclic
frameworks.
By
using
reaction,
in
addition
to
accessing
tetrahydroquinolines,
quinolines
and
julolidines
single
step,
it
is
possible
form
following
new
bonds:
two
Csp
3–Csp
3
one
3–Nsp
3,
2–Csp
2
2–Nsp
2,
four
1,
respectively.
This
short
review
discusses
main
features
including
its
mechanism,
scope
by
employing
different
catalysts
substrates,
as
well
stereoselective
versions.
1
Introduction
Mechanism
Reaction
Tetrahydroquinolines
4
Quinolines
5
Julolidines
6
Concluding
Remarks
Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
12(9)
Published: July 29, 2023
Abstract
Multicomponent
reactions
(MCRs)
have
emerged
as
powerful
tools
in
synthetic
chemistry
for
the
efficient
synthesis
of
diverse
molecular
scaffolds,
particularly
nitrogen‐containing
heterocycles.
Despite
their
numerous
advantages,
use
transition
metal
catalysts
or
additives
MCRs
can
present
limitations
due
to
cost,
toxicity,
and
environmental
concerns.
In
recent
years,
there
has
been
a
growing
interest
metal‐free
N
‐heterocyclic
compounds.
This
review
provides
comprehensive
concise
overview
advancements
valuable
‐heterocycles
over
past
five
years.
The
is
systematically
organized,
categorizing
discussed
based
on
size
heterocyclic
ring
number
nitrogen
atoms.
Only
that
result
formation
rings
containing
at
least
one
atom
are
included,
while
derivatization
using
falls
outside
scope
this
review.
By
highlighting
developments
field,
aims
showcase
potential
significance
sustainable
strategies
accessing
elimination
metals
not
only
simplifies
reaction
conditions
but
also
contributes
greener
more
environmentally
friendly
approaches.
serves
resource
researchers
interested
design
application
Reaction Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
8(6), P. 1324 - 1333
Published: Jan. 1, 2023
The
fructose
was
subjected
to
a
dehydration
reaction
produce
5-hydroxymethylfurfural
using
deep
eutectic
solvent
composed
of
choline
chloride,
fructose,
water
as
the
third
component
mixture
and
p
-sulfonic
acid
calix[4]arene
an
organocatalyst.
Reaction Chemistry & Engineering,
Journal Year:
2022,
Volume and Issue:
7(10), P. 2132 - 2140
Published: Jan. 1, 2022
Acetals
formed
from
glycerol
find
applications
in
several
areas,
their
use
as
fuel
additives
being
the
most
promising,
since
it
results
total
integration
biodiesel
chain
and
eliminates
one
of
obstacles
to
its
production.
Journal of Heterocyclic Chemistry,
Journal Year:
2021,
Volume and Issue:
58(8), P. 1594 - 1600
Published: April 28, 2021
Abstract
In
this
report,
synthesis
of
julolidines
via
one‐pot
cascade
reaction
aniline
derivatives
with
a
mixture
styrene
and
formaldehyde
in
the
presence
silica
sulfuric
acid
as
an
efficient
catalyst
has
been
studied
under
aerobic
condition.
By
presented
method,
various
are
obtained
mild
transition
metal‐free
conditions.
The
is
proceeded
imine
formation
followed
by
Aza‐Diels‐Alder
cycloaddition
gave
julolidine
derivatives.
can
be
recycled
reused
multiple
times
to
catalyze
reaction.
