Silicon and Carbon nanocages as catalysts of CO 2 reduction reaction DOI Creative Commons

XiLan Li,

Jing Wang, Xiaoli Wei

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: July 10, 2023

Abstract In this study, the catalytic abilities of on Ni-C 50 and Ni-Si nanocages for CO 2 reduction reaction to CO, CH 4 , HCOOH, HCHO 3 OH creation are examined by theoretical methods. The possible mechanisms ΔG steps produce calculated. Results indicated that, rate limiting step production is nanocage-*CO → nanocage-*CHO nanocages. shown that overpotential lower than various metal catalysts. It can be concluded nanocage has more negative values free barrier energy process reduction. demonstrated HCOOH Finally, proposed as novel catalysts species.

Language: Английский

Harnessing alcohols as sustainable reagents for late-stage functionalisation: synthesis of drugs and bio-inspired compounds DOI
Sourajit Bera, Lalit Mohan Kabadwal, Debasis Banerjee

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(9), P. 4607 - 4647

Published: Jan. 1, 2024

This review collectively discussed the utilisation of alcohols in various organic transformations and their application toward intermediates drugs, drug derivatives natural product-like molecules.

Language: Английский

Citations

16
N-Alkylation of Amines by C1–C10 Aliphatic Alcohols Using A Well-Defined Ru(II)-Catalyst. A Metal–Ligand Cooperative Approach DOI
Amit Kumar Guin, Subhasree Pal, Subhajit Chakraborty

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(9), P. 5944 - 5961

Published: April 13, 2023

A Ru(II)-catalyzed efficient and selective N-alkylation of amines by C1-C10 aliphatic alcohols is reported. The catalyst [Ru(L1a)(PPh3)Cl2] (1a) bearing a tridentate redox-active azo-aromatic pincer, 2-((4-chlorophenyl)diazenyl)-1,10-phenanthroline (L1a) air-stable, easy to prepare, showed wide functional group tolerance requiring only 1.0 mol % (for N-methylation N-ethylation) 0.1 loading for with C3-C10 alcohols. array N-methylated, N-ethylated, N-alkylated were prepared in moderate good yields via direct coupling 1a efficiently catalyzes the diamines selectively. It even suitable synthesizing using (aliphatic) diols producing tumor-active drug molecule MSX-122 yield. excellent chemo-selectivity during oleyl alcohol monoterpenoid β-citronellol. Control experiments mechanistic investigations revealed that 1a-catalyzed reactions proceed borrowing hydrogen transfer pathway where removed from dehydrogenation step stored ligand backbone 1a, which subsequent steps transferred situ formed imine intermediate produce amines.

Language: Английский

Citations

22
Recent Advances on Direct Functionalization of Indoles in Aqueous Media DOI
Qiwen Pang,

Wei‐Fang Zuo,

Yang Zhang

et al.

The Chemical Record, Journal Year: 2023, Volume and Issue: 23(3)

Published: Feb. 1, 2023

Abstract Indoles and their derivatives have dominated a significant proportion of nitrogen‐containing heterocyclic compounds play an essential role in synthetic medicinal chemistry, pesticides, advanced materials. Compared with conventional strategies, direct functionalization indoles provides straightforward access to construct diverse indole scaffolds. As we enter era emphasizing green sustainable utilizing environment‐friendly solvents represented by water demonstrates great potential synthesizing valuable derivatives. This review aims depict the critical aspects aqueous‐mediated over past decade discusses future challenges prospects this fast‐growing field. For convenience readers, is classified into three parts according bonding modes (C−C, C−N, C−S bonds), which focus on diversity derivatives, prominent chemical process, types catalyst systems mechanisms. We hope can promote development discovery novel practical organic methods aqueous phase.

Language: Английский

Citations

18
Lanthanide/B(C6F5)3-Promoted Hydroboration Reduction of Indoles and Quinolines with Pinacolborane DOI
Jianping Zhang, Ziyan Chen, Mingxin Chen

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(2), P. 887 - 897

Published: Jan. 5, 2024

We have developed a lanthanide/B(C6F5)3-promoted hydroboration reduction of indoles and quinolines with pinacolborane (HBpin). This reaction provides streamlined access to range nitrogen-containing compounds in moderate excellent yields. Large-scale synthesis further transformations bioactive indicate that the method has potential practical applications. Preliminary mechanistic studies suggest amine additives promote formation indole-borane intermediates, proceeds via intermediates HBpin situ-formed BH3 species, followed by protodeborylation process.

Language: Английский

Citations

7
Transition-Metal-Catalyzed Remote C–H Bond Functionalization of Cyclic Amines DOI Creative Commons
Weijie Chen, Xiaoyu Yang, Xi Cao

et al.

SynOpen, Journal Year: 2022, Volume and Issue: 06(04), P. 286 - 305

Published: Aug. 24, 2022

Abstract C–H bond functionalization is one of the most effective strategies for rapid synthesis cyclic amines containing substituents on ring, which are core structures many bioactive molecules. However, it much more challenging to perform this strategy remote bonds compared α-C–H amines. This graphical review aims provide a concise overview transition-metal-catalyzed methods Examples categorized and demonstrated according mechanistic pathways that initiate reactions amine substrates. Where relevant, selected substrate scope detailed reaction mechanisms given.

Language: Английский

Citations

19
Utilization of methanol for condensation interrupted chemoselective transfer hydrogenation of CC, CO, and CN bonds under low catalyst loading DOI

Anirban Sau,

Divya Mahapatra,

Sadhan Dey

et al.

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(9), P. 2274 - 2286

Published: Jan. 1, 2023

Selective transfer hydrogenation (TH) of unsaturated molecules using methanol is challenging as the in situ generated formaldehyde prone to react with active methylene ( C -methylation) or amine N core desired product.

Language: Английский

Citations

12
Multi-hydroxyl POSS supported iridium complexes as a recyclable catalyst for selective synthesis of N-/C-substituted indoles and the total synthesis of HIV-1 fusion inhibitor DOI
Jiahao Li, Li Chen, Likui Wang

et al.

Journal of Catalysis, Journal Year: 2023, Volume and Issue: 429, P. 115205 - 115205

Published: Nov. 24, 2023

Language: Английский

Citations

12
Synthesis of Pyrazines from Biomass-Derived Vicinal Diols Using Ammonia over Heterogeneous Pt/CeO2/Al2O3 Catalysts DOI
Zhitong Zhou, Weixiang Guan, Xiaoli Pan

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 5664 - 5673

Published: March 21, 2025

Language: Английский

Citations

0
Tandem synthesis of N-methylated tertiary amines via three-component coupling of carbonyl compounds, amines, and methanol DOI
Ishani Borthakur,

Sameer Srivastava,

Saloni Kumari

et al.

Chemical Communications, Journal Year: 2022, Volume and Issue: 58(70), P. 9822 - 9825

Published: Jan. 1, 2022

An Ir-catalyzed tandem synthesis of various N-methylated tertiary amines from three-component coupling carbonyl compounds, amines, and methanol following reductive amination/N-methylation is reported for the first time. A wide array substrates with tolerance different functional groups was demonstrated. The protocol extended to N-methyl containing pharmaceutically important drug molecules. probable catalytic cycle proposed based on control experiments analytical techniques such as NMR, IR ESI-MS.

Language: Английский

Citations

14
Nickel-Catalyzed Direct Synthesis of N-Substituted Indoles from Amino Alcohols and Alcohols DOI
Vinita Yadav,

Sayali G. Jagtap,

Ekambaram Balaraman

et al.

Organic Letters, Journal Year: 2022, Volume and Issue: 24(49), P. 9054 - 9059

Published: Dec. 5, 2022

A one-pot cascade approach for the synthesis of N-substituted indoles from amino alcohols and under additive base-free conditions with liberation water as only stoichiometric byproduct is reported. The commercially available bench-stable Ni(OTf)2 salt in combination 1,2-bis(dicyclohexylphosphino)ethane (dcype) very effective this unprecedented catalytic transformation. broad range substrates including aromatic aliphatic primary alcohols, cyclic acyclic secondary various substituted 2-aminophenyl ethyl are employed reaction to provide a diverse N-alkylated indoles. Mechanistic studies revealed that proceeds through tandem N-alkylation via hydrogen autotransfer followed by cyclization alcohol intermediate.

Language: Английский

Citations

13