Synthesis,
Journal Year:
2023,
Volume and Issue:
56(01), P. 47 - 54
Published: Nov. 23, 2023
Abstract
A
phosphonium-assisted
C–H
cyclization
with
iodonium
ylides
has
been
developed
under
redox-neutral
rhodium(III)
catalysis,
offering
a
wide
variety
of
valuable
isocoumarins
in
moderate
to
good
yields.
This
transformation
proceeds
through
activation,
carbene
insertion,
and
nucleophilic
addition
processes.
The
reaction
occurs
low
catalyst
loading
short
time
does
not
require
an
oxidant.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(9), P. 2512 - 2517
Published: Jan. 1, 2024
A
Rh(
iii
)-catalysed
cascade
C–H
functionalization/[3
+
2]
dipolar
cycloaddition
was
realized
to
deliver
gem
-difluorinated
pentacyclic
indenopyrazolopyrazolones
with
four
continuous
chiral
carbon
centres
in
a
one-pot
fashion.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(25), P. 3775 - 3778
Published: Jan. 1, 2023
An
efficient
method
for
the
construction
of
various
3,4,5-trisubstituted
phenol
derivatives
has
been
achieved
via
Rh(III)-catalyzed
coupling
phosphonium
cations
with
internal
alkynes.
This
protocol
shows
good
substrate
compatibility,
as
an
array
structurally
and
electronically
diverse
compounds
react
efficiently
up
to
87%
yield.
Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
21(4), P. 775 - 782
Published: Dec. 19, 2022
A
rhodium-catalyzed
formal
[4
+
1]-cyclization
reaction
of
aryl
substituted
pyrazoles
with
cyclopropanols
via
C-H
bond
activation/cyclization
processes
to
selectively
construct
a
series
carbonyl
functionalized
pyrazolo[5,1-a]isoindoles
is
described.
The
features
good
functional
group
compatibility
and
broad
substrate
scope
respect
both
cyclization
components
up
84%
yields.
Mechanistic
studies
indicated
that
the
cleavage
might
be
rate-determining
step
in
this
transformation.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 19, 2024
An
efficient
method
for
construction
of
various
fluorenones
has
been
achieved
via
Rh(III)-catalyzed
C–H
activation/[4
+
2]
annulation/aromatization
sequences
simple
and
readily
available
enaminones
1,3-dienes.
This
protocol
showed
good
substrate
compatibility
as
an
array
structurally
electronically
diverse
prepared
efficiently
in
moderate
to
yields
preparative
scale
utility
showing
very
efficiency
the
late-stage
functionalization
complex
valuable
molecules.
Applied Organometallic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 13, 2024
ABSTRACT
A
highly
regioselective
approach
for
constructing
4‐cyclobutene‐isoquinoline
derivatives
through
ruthenium‐catalyzed
domino
C–H
activation/cyclization
of
aryl
imidates
has
been
demonstrated.
This
new
transformation
tolerates
various
substituted
functional
groups
on
and
propargylic
monofluoroalkynes,
resulting
in
the
corresponding
products
being
delivered
moderate
yields.
