A Multicomponent [2+2+1] Cascade Cyclization to Synthesize Thiazol-2(3H)-one DOI
Mingxu Wang, Yuefa Gong, Yuqi Shi

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

A multicomponent [2+2+1] tandem cyclization of alkynones with amines and water using potassium thiocyanate as electrolyte raw material to access thiazol-2(3

Language: Английский

Three Component Synthesis of 4‐Aryl‐2‐aminothiazoles under Transition‐Metal Free Conditions DOI

Xi Cheng,

Da‐Bin Qin,

Zhi‐Bing Dong

et al.

European Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 26(39)

Published: Aug. 25, 2023

Abstract An efficient three‐component synthesis of 4‐aryl‐2‐aminothiazoles was reported. Phenyl‐thioureas reacted with 2‐bromoacetophenones to form through cyclization, and the subsequent C−N bonding benzyl/allyl bromides gave desired disubstituted thiazoles smoothly. The protocol features transition‐metal free, short reaction time, easily available starting materials, good yields broad substrate scope, showing potential synthetic value for a variety biologically or pharmaceutically active compounds.

Language: Английский

Citations

2
Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Environmentally Fridendly Synthesis of Functionalized Fused 2-Iminothiazolines DOI

Shu Shu Yang,

Tingting Guo, Jianbo Ma

et al.

Published: Jan. 1, 2024

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

Language: Английский

Citations

0
Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Synthesis of Functionalized Fused 2-Iminothiazolines DOI

Shu Shu Yang,

Tingting Guo, Jianbo Ma

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13678 - 13690

Published: Sept. 6, 2024

Herein, a visible-light-promoted radical cascade cyclization of heterocyclic ketene aminals (HKAs) and thiocyanates was developed to access functionalized fused 2-iminothiazolines. This novel reaction can be realized under only visible-light irradiation without the help external photocatalysts, oxidants, additives. These multicomponent reactions demonstrate excellent selectivity for

Language: Английский

Citations

0
α-Thiocyanato ketones in the synthesis of heterocycles (microreview) DOI
V. K. Kindop, А. В. Беспалов, В. В. Доценко

et al.

Chemistry of Heterocyclic Compounds, Journal Year: 2024, Volume and Issue: 60(7-8), P. 345 - 347

Published: Aug. 1, 2024

Language: Английский

Citations

0
A Multicomponent [2+2+1] Cascade Cyclization to Synthesize Thiazol-2(3H)-one DOI
Mingxu Wang, Yuefa Gong, Yuqi Shi

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

A multicomponent [2+2+1] tandem cyclization of alkynones with amines and water using potassium thiocyanate as electrolyte raw material to access thiazol-2(3

Language: Английский

Citations

0