Synthesis of Γ-Keto Sulfones Through Sulfonylation/Acylation of Alkenes Merging Nhc- and Photo-Catalysis DOI
Jie Liu,

Xu Sun,

Gan Zhang

et al.

Published: Jan. 1, 2024

Language: Английский

Photoredox/HAT-Catalyzed Intramolecular Hydrocyclization of Alkenes toward 2,3-Fused Quinazolinones and Dihydroquinazolinones DOI
Dong Li,

Xiaoqing Wang,

Yanhui Gou

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 2, 2024

New photochemical approaches to 2,3-fused quinazolinones and dihydroquinazolinones are disclosed. The intramolecular hydrocyclization proceeds in moderate excellent yields across diverse alkenes with high regioselectivity diastereocontrol. Mechanistic studies indicated that the radical cascade processes involve thiophenol acting as single-electron transfer hydrogen atom reagents. success of gram-scale synthesis proves strategy can be used for practical applications.

Language: Английский

Citations

1
Photocatalyzed Acylmethylation/Cyclization of Unactivated Alkenes with Sulfoxonium Ylides towards Acylmethylated Polycyclic Quinazolinones DOI

Yechun Wu,

Lingli Liu, Jin‐Tao Yu

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: unknown

Published: May 16, 2024

Abstract The synthesis of acylmethylatated pyrrolo‐quinazolinones was developed via photo‐induced cascade radical addition/cyclization N ‐(but‐3‐enyl)quinazolin‐4(3 H )‐ones with sulfoxonium ylides using 4CzIPN as the photocatalyst. This approach also suitable for construction piperidino‐quinazolinones. protocol features mild conditions, convenient operation, broad substrate scope and good functional group compatibility.

Language: Английский

Citations

0
Visible-light-induced selective hydrolipocyclization and silylation of alkenes: access to ring-fused quinazolin-4(3H)-ones and their silicon-substituted derivatives DOI
Shoucai Wang, Ziren Chen, Fei Xue

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(21), P. 6019 - 6025

Published: Jan. 1, 2024

A visible-light-induced intermolecular silylation and hydrolipocyclization using hydrosilane as the hydrogen silicon source has been developed, which provided an efficient pathway for synthesis of organosilanes polycyclic quinazolinones.

Language: Английский

Citations

0
Mn-Catalyzed Electrooxidative Radical Cascade Cyclization for the Synthesis of 6-Phosphorylated Quinoxalino[2,1-b]quinazolin-12-ones DOI
Huanping Xie,

Jiongjiong Duan,

Yi Cao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Due to their important potential medicinal value, chemists are pursuing mild and efficient methods synthesize structurally diverse quinazolinone derivatives. In this paper, a series of isocyano-tethered

Language: Английский

Citations

0
Synthesis of Γ-Keto Sulfones Through Sulfonylation/Acylation of Alkenes Merging Nhc- and Photo-Catalysis DOI
Jie Liu,

Xu Sun,

Gan Zhang

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0