A
simple
yet
efficient
approach
towards
the
synthesis
of
β-hydroxy
selenylated
ketones
was
developed
from
easily
accessible
chalcones
and
diphenyl
diselenide
through
an
electrochemical
pathway.
In
this
technique,
water
are
source
PhSe.
hydroxyl
(-OH)
groups
that
can
be
inserted
at
α
β
positions
respectively
producing
in
moderate
to
good
yields.
The
reaction
features
difunctionalization
ketones,
catalyst
free,
mild
conditions,
stereo
regioselectivity
undivided
cell
room
temperature.
For
transformation,
a
plausible
radical
mechanism
has
been
put
out.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(14), P. 3160 - 3165
Published: May 25, 2024
Abstract
A
visible‐light‐induced
method
was
developed
to
synthesize
selenylated
cyclic
boronic
esters
through
intermolecular
oxyselenenylation.
This
can
be
performed
under
additive‐free
and
photocatalyst‐free
conditions
generates
potentially
pharmaceutically
useful
heterocycles.
plausible
reaction
mechanism
proposed
based
on
several
control
experiments
previous
reports.
Applied Organometallic Chemistry,
Journal Year:
2023,
Volume and Issue:
37(10)
Published: Aug. 19, 2023
A
three‐component
reaction
of
olefins,
indoles,
and
diaryl
diselenides
catalyzed
by
copper
chloride
under
irradiation
blue
LED
light
is
disclosed.
Various
including
diheteroaryl
are
suitable
for
this
bifunctionalization
olefins.
This
protocol
provides
26
examples
β‐(hetero)arylselenyl
indoles
in
60%–87%
yields.
The
proposed
mechanism
involves
activation
coordination
with
chloride,
generation
arylselenium
cations
heterolysis
activated
diselenides,
electrophilic
addition
to
styrenes,
then
Friedel–Crafts‐type
alkylation
at
the
3‐position
NH‐indoles.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
366(3), P. 408 - 413
Published: Dec. 15, 2023
Abstract
An
electrocatalytic
approach
for
the
bromide‐mediated
selenocyclization
of
N
‐propargylamides
with
diselenides
is
described,
providing
a
synthetic
route
synthesis
various
seleno‐oxazoles
in
41–73%
yields.
The
success
gram‐scale
experiments
demonstrate
potential
value
this
protocol
chemistry.
Mechanistic
investigations
suggest
that
proceed
through
two
possible
pathways,
including
selenium
cation
and
radical
processes.
Chemistry - An Asian Journal,
Journal Year:
2023,
Volume and Issue:
19(1)
Published: Nov. 11, 2023
Organochalcogen
molecules
have
extensive
applications
in
various
fields.
They
serve
as
pharmaceuticals,
ligands,
organocatalysts,
agrochemicals,
and
other
functional
materials.
Difunctionalization
of
olefins,
which
belong
to
a
class
multicomponent
reactions,
is
successful
technique
for
introducing
two
moieties
single-step
reaction,
both
terms
atom
economy
step
economy.
The
difunctionalization
olefins
with
diorganyl
dichalcogenides
may
effectively
increase
the
molecular
complexity,
has
achieved
significant
advancements
recent
decades.
This
article
describes
diselenides
disulfides.
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 3, 2024
Comprehensive
Summary
Unsymmetric
sulfides
and
selenides
have
great
applications
in
the
pharmaceutical
field.
Herein,
we
describe
reductive
coupling
reaction
of
xanthate
esters
with
sulfur‐containing
selenium‐containing
compounds
(thio(seleno)sulfonates
disulfides(selenides))
under
nickel‐catalyzed
condition.
It
provides
a
mild
effective
method
for
synthesis
unsymmetric
which
has
advantages
conditions,
high
yields
wide
range
substrates.
The Chemical Record,
Journal Year:
2024,
Volume and Issue:
24(7)
Published: July 1, 2024
Abstract
Diorganyl
diselenides
have
emerged
as
privileged
structures
because
they
are
easy
to
prepare,
distinct
reactivity,
and
broad
biological
activity.
They
also
been
used
in
the
synthesis
of
natural
products
an
electrophile
organoselenylation
aromatic
systems
peptides,
reductions
alkenes,
nucleophilic
substitution.
This
review
summarizes
advancements
methods
for
transformations
promoted
by
diorganyl
main
functions
organic
chemistry.
Parallel,
it
will
describe
findings
on
pharmacology
toxicology
diselenides,
emphasizing
anti‐inflammatory,
hypoglycemic,
chemotherapeutic,
antimicrobial
activities.
Therefore,
examination
detailing
reactivity
characteristics
provides
valuable
insights
academic
researchers
industrial
professionals.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(32), P. 23147 - 23151
Published: Jan. 1, 2024
Zn(OTf)2-catalyzed
intra-
and
intermolecular
selenofunctionalization
of
alkenes
was
achieved
with
electrophilic
N-phenylselenophthalimide.
This
method
provides
straightforward
efficient
access
to
various
seleno-substituted
heterocycles
vicinal
Se
heteroatom-disubstituted
molecules
under
mild
conditions.
reaction
is
compatible
substrates/functional
groups,
preliminary
studies
on
the
mechanistic
were
also
conducted.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(47), P. 34811 - 34815
Published: Jan. 1, 2024
The
σ-complex
is
formed
first,
followed
by
the
production
of
two
adduct
isomers,
and
ultimately
yielding
desired
product
through
an
elimination
reaction.
