Construction of N-Ferrocene Substituted Benzodihydrooxazoles via a Catalyst-Free Aza-Michael Addition/C(sp3)-O Bond Formation Tandem Reaction DOI Creative Commons
Mingliang Zhang,

Zhao Pin,

Qilv Liu

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(14), P. 5615 - 5615

Published: July 24, 2023

A catalyst-free aza-Michael addition/C(sp3)-O bond formation tandem reaction of substituted amino ferrocenes with quinone esters was developed, which provided a green and efficient strategy for the construction C(sp3)-O from C(sp3)-H, series N-ferrocene-substituted benzodihydrooxazoles were smoothly produced in moderate to excellent yields (up >99% yield). The mechanism experiments showed that performed as both substrate oxidant. salient features this transformation include good functional group tolerance, broad scope mild conditions.

Language: Английский

Construction of N-Ferrocene Substituted Benzodihydrooxazoles via a Catalyst-Free Aza-Michael Addition/C(sp3)-O Bond Formation Tandem Reaction DOI Creative Commons
Mingliang Zhang,

Zhao Pin,

Qilv Liu

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(14), P. 5615 - 5615

Published: July 24, 2023

A catalyst-free aza-Michael addition/C(sp3)-O bond formation tandem reaction of substituted amino ferrocenes with quinone esters was developed, which provided a green and efficient strategy for the construction C(sp3)-O from C(sp3)-H, series N-ferrocene-substituted benzodihydrooxazoles were smoothly produced in moderate to excellent yields (up >99% yield). The mechanism experiments showed that performed as both substrate oxidant. salient features this transformation include good functional group tolerance, broad scope mild conditions.

Language: Английский

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