An efficient heterogeneous copper oxide nanocatalyst for N-alkylation of amines with carbonyl compounds under H2 atmosphere DOI Creative Commons

M. Sharath Babu,

N. Padmaja,

G. Bhagavanth Reddy

et al.

Results in Chemistry, Journal Year: 2023, Volume and Issue: 5, P. 100947 - 100947

Published: Jan. 1, 2023

The aim of this research is to investigate the potential copper oxide nanoparticles (CuO NPs) as a catalyst for reductive N-alkylation amines with carbonyl compounds in order synthesize secondary an H2 environment. synthesized CuO NPs were characterized using UV–vis DRS, XRD, FT-IR, and TEM techniques, which confirmed their spherical shape, monoclinic phase, average diameter 9 ± 2 nm. results catalytic study indicate that was able produce various excellent yield. also explored effects reaction time, temperature, weight under optimum conditions. Additionally, shown be highly stable could reused three cycles without any loss activity formation amines.

Language: Английский

Highly dispersed ruthenium capsulated in UiO-66-NH2 for hydrogen-borrowing-mediated N-alkylation reactions DOI
Jiahao Li,

Shiguo Ou,

Xinxin Sang

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(7), P. 1958 - 1966

Published: Jan. 1, 2024

Herein, atomically dispersed Ru sites are encapsulated within UiO-66–NH 2 frameworks to serve as a highly active, selective, and stable catalyst for amine synthesis via N -alkylation reactions of o -phenylenediamine with monohydric alcohols.

Language: Английский

Citations

4
Temperature-dependent switchable synthesis of imines and amines via coupling of alcohols and amines using pyrrolyl-imine ruthenium catalysts DOI
Qing Li, Yu Hou,

Mengxuan Bai

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 115895 - 115895

Published: Dec. 1, 2024

Language: Английский

Citations

3
N-Heterocyclic carbene supported zinc catalysed N-formylation of diverse N–H functionalities with carbon dioxide under ambient conditions DOI

Sangita Sahoo,

Subarna Manna,

Arnab Rit

et al.

Catalysis Science & Technology, Journal Year: 2023, Volume and Issue: 13(11), P. 3344 - 3350

Published: Jan. 1, 2023

A heteroditopic NHC ligand supported Zn-catalysed RT N -formylation of diverse N–H moieties with CO 2 (1 bar) using PhSiH 3 was developed, which offers excellent functional group tolerance, chemoselectivity, and synthons for biologically relevant compounds.

Language: Английский

Citations

8
Control over borrowing hydrogen and acceptorless dehydrogenative coupling process for the Co(iii)–NHC catalysed chemoselective alkylation and cyclisation of 1,2-phenylenediamine with alcohols DOI

Misba Siddique,

Biswaranjan Boity,

Arnab Rit

et al.

Catalysis Science & Technology, Journal Year: 2023, Volume and Issue: 13(24), P. 7172 - 7180

Published: Jan. 1, 2023

Chemoselective alkylation and cyclisation of 1,2-phenylenediamine with alcohols via control cobalt–NHC catalysed borrowing hydrogen acceptorless dehydrogenative coupling is achieved by tuning the triazole substituent NHC ligand system.

Language: Английский

Citations

6
Heteroditopic NHC Ligand Supported Manganese(I) Complexes: Synthesis, Characterization, and Activity as Non‐bifunctional Phosphine‐Free Catalyst for the α‐Alkylation of Nitriles DOI
S. N. R. Donthireddy, Arnab Rit

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 30(1)

Published: Oct. 9, 2023

Abstract In the present work, several manganese(I) complexes of chelating heteroditopic ligands Mn1–3 , featuring ImNHC (imidazol‐2‐ylidene) connected to a 1,2,3‐triazole‐N or tzNHC (1,2,3‐triazol‐5‐ylidene) donors via methylene spacer, with possible modifications at triazole backbone have been synthesized and completely characterized. Notably, CO stretching frequencies, electrochemical analysis, frontier orbital analysis certainly suggest that ImNHC‐tzNHC stronger donation capabilities than related ImNHC‐Ntz ligand in complexes. Moreover, these well‐defined phosphine‐free Mn(I)−NHC found be effective non‐bifunctional catalysts for α‐alkylation nitriles using alcohols importantly, catalyst Mn1 containing weaker triazole‐N donor displayed higher activity compared Mn2 / Mn3 an unsymmetrical bis‐carbene (ImNHC tzNHC). A wide range aryl were coupled diverse (hetero)aromatic as well aliphatic get corresponding products good excellent yields (32 examples, up 95 % yield). The detailed mechanistic studies including deuterium labelling experiments reveal reaction follows Borrowing Hydrogen pathway.

Language: Английский

Citations

5
Development of a Mild and Efficient Process for Ir-Catalyzed N-Alkylation of 4-Bromopyridin-2-amine with a Primary Alcohol via Borrowing Hydrogen DOI
Sri Krishna Nimmagadda, K. Srinivas,

Siva Sankar Bondigela

et al.

Organic Process Research & Development, Journal Year: 2024, Volume and Issue: 28(8), P. 3414 - 3422

Published: July 25, 2024

We report herein the development and scale up of an Ir-catalyzed N-alkylation reaction between a 4-bromopyridin-2-amine (1) (4-(5-(1,1-difluoroethyl)-1,2,4-oxadiazol-3-yl)bicyclo[2.2.2]octan-1-yl)methanol (2) proceeding via borrowing hydrogen process. The traditional approach alcohol oxidation followed by reductive amination posed challenges that are attributed to poor nucleophilicity 2-aminopyridine derivative resulting in lower isolated yields. Several catalysts bases were evaluated for successful 1 with 2, Ir (III) catalyst combination LiOt-Bu as base was found provide optimal conversion. process successfully demonstrated on 1.5 kg afforded >70% yield 3 without need sealed reactor or any other specialized equipment.

Language: Английский

Citations

1
Construction of C–X (X = N, O) bonds from benzyl alcohols via Cu-BTC-catalyzed oxidative coupling DOI

Yujuan Wu,

Lianji Zhang,

Huimin Liu

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(15), P. 4366 - 4375

Published: Jan. 1, 2024

Herein, an efficient and environmentally friendly Cu-BTC catalytic system is reported, which can be successfully applied to the oxidative coupling of benzyl alcohols for construction C–X (X = N, O) bonds.

Language: Английский

Citations

1
An efficient heterogeneous copper oxide nanocatalyst for N-alkylation of amines with carbonyl compounds under H2 atmosphere DOI Creative Commons

M. Sharath Babu,

N. Padmaja,

G. Bhagavanth Reddy

et al.

Results in Chemistry, Journal Year: 2023, Volume and Issue: 5, P. 100947 - 100947

Published: Jan. 1, 2023

The aim of this research is to investigate the potential copper oxide nanoparticles (CuO NPs) as a catalyst for reductive N-alkylation amines with carbonyl compounds in order synthesize secondary an H2 environment. synthesized CuO NPs were characterized using UV–vis DRS, XRD, FT-IR, and TEM techniques, which confirmed their spherical shape, monoclinic phase, average diameter 9 ± 2 nm. results catalytic study indicate that was able produce various excellent yield. also explored effects reaction time, temperature, weight under optimum conditions. Additionally, shown be highly stable could reused three cycles without any loss activity formation amines.

Language: Английский

Citations

0