1,6-Conjugate addition of in situ generated aryldiazenes to p-quinone methides
Ajay G. Mamale,
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Sayantan Paul,
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Rajesh G. Gonnade
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et al.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(27), P. 5636 - 5645
Published: Jan. 1, 2024
Herein
we
report
a
transition-metal
free,
base-mediated
1,6-conjugate
addition
of
aryldiazenes
to
para
-quinone
methides
(
p
-QMs).
Language: Английский
Solvent Dictated Organic Transformations
Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 7, 2024
Solvent
plays
an
important
role
in
many
chemical
reactions.
The
C-H
activation
has
been
one
of
the
most
powerful
tools
organic
synthesis.
These
reactions
are
often
assisted
by
solvents
which
not
only
provide
a
medium
for
but
also
facilitate
reaching
to
product
stage.
solvent
helps
reaction
profile
both
chemically
and
energetically
reach
targeted
product.
Organic
transformations
via
from
assistance
perspective
discussed
this
review.
Various
such
as
tetrahydrofuran
(THF),
MeCN,
dichloromethane
(DCM),
dimethoxyethane
(DME),
1,2-dichloroethane
(1,2-DCE),
dimethylformamide
(DMF),
dimethylsulfoxide
(DMSO),
isopropyl
nitrile
(
Language: Английский
C6–H Bond Functionalization of Indoles: A New Gate
Synthesis,
Journal Year:
2023,
Volume and Issue:
55(21), P. 3417 - 3433
Published: March 8, 2023
Abstract
Indoles
are
valuable
precursors
in
medicinal,
bioorganic,
and
material
chemistry
particularly
serve
as
a
platform
for
diversity.
However,
the
scope
of
C6-functionalization
indoles
was
limited
until
recently.
In
this
short
review,
we
summarize
developments
reactions
involving
transition-metal-catalyzed
functionalization
Brønsted
Lewis
acid
catalyzed
processes.
The
regioselectivity
is
controlled
by
remote-C–H
activation
hydrogen
bond
formation.
1
Introduction
2
Transition-Metal-Catalyzed
Functionalization
3
Acid-Catalyzed
Processes
4
Conclusion
Language: Английский