Royal Society of Chemistry eBooks,
Journal Year:
2023,
Volume and Issue:
unknown, P. 301 - 330
Published: Dec. 20, 2023
Since
its
discovery
in
1971,
artemisinin
has
been
and
continues
to
be
at
the
forefront
of
fight
against
malaria.
The
commercial
importance
this
compound
fuelled
historical
breakthrough
innovations
over
past
decades.
Among
them,
synthetic
biology
photochemistry
have
two
transformative
technologies.
focus
book
chapter
is
highlight
tremendous
developments
which
made
field
context.
This
summarizes
early
investigations
on
biosynthesis
total
synthesis
involving
as
a
key
step,
led
foundation
today’s
large
scale
photochemical
process
developed
operated
by
Sanofi
2013.
However,
market
competition
further
investments
developments,
particular
using
continuous
flow
reactors
more
recently,
development
new
recyclable
bifunctional
photocatalytic
systems
well
routes
become
increasingly
cost-efficient
sustainable.
JACS Au,
Journal Year:
2024,
Volume and Issue:
4(8), P. 2746 - 2766
Published: Aug. 8, 2024
Photocatalysis
is
a
versatile
and
rapidly
developing
field
with
applications
spanning
artificial
photosynthesis,
photo-biocatalysis,
photoredox
catalysis
in
solution
or
supramolecular
structures,
utilization
of
abundant
metals
organocatalysts,
sustainable
synthesis,
plastic
degradation.
In
this
Perspective,
we
summarize
conclusions
from
an
interdisciplinary
workshop
young
principal
investigators
held
at
the
Lorentz
Center
Leiden
March
2023.
We
explore
how
diverse
fields
within
photocatalysis
can
benefit
one
another.
delve
into
intricate
interplay
between
these
subdisciplines,
by
highlighting
unique
challenges
opportunities
presented
each
multidisciplinary
approach
drive
innovation
lead
to
solutions
for
future.
Advanced
collaboration
knowledge
exchange
across
domains
further
enhance
potential
photocatalysis.
Artificial
photosynthesis
has
become
promising
technology
solar
fuel
generation,
instance,
via
water
splitting
CO
Journal of the American Chemical Society,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 28, 2025
Iron
is
the
most
abundant
transition
metal
element
and
would
be
ideal
replacement
for
noble
metals
in
many
applications
that
rely
on
luminescent
long-lived
electronically
excited
states.
We
show
efficient
reversible
energy
transfer
between
doublet
states
of
iron
complexes
triplet
organic
ligands
improves
storage
by
up
to
350-fold.
As
a
result,
luminescence
lifetimes
100
ns
are
achieved,
upconversion
from
red
blue
light
becomes
68
times
more
yield
benchmark
photoredox
reactions
significantly
improved.
These
advances
make
coordination
compounds
promising
candidates
lighting,
solar
conversion
photocatalysis.
Organic Process Research & Development,
Journal Year:
2024,
Volume and Issue:
28(8), P. 3307 - 3312
Published: July 24, 2024
A
continuous
flow
approach
for
the
aerobic
photo-oxidation
of
benzylic
substrates
to
ketone
and
aldehyde
products
is
presented.
The
resulting
process
exploits
UV-A
LEDs
(375
nm)
in
combination
with
a
Corning
AFR
reactor
that
ensures
effective
gas-liquid
mixing
leads
short
residence
times
1
min.
variety
are
converted
their
corresponding
carbonyl
products,
scalability
demonstrated
produce
multigram
quantities
within
few
hours.
Overall,
this
offers
several
improvements
over
alternative
oxidation
methods
due
combined
use
air
as
an
oxidant
SAS
(sodium
anthraquinone-2
sulfonate)
water-soluble
photocatalyst.
greener
safer
conditions
together
intensification
principles
renders
attractive
further
industrial
applications.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
366(2), P. 168 - 182
Published: Dec. 16, 2023
Abstract
Photoinduced
chemical
transformations
have
become
a
promising
aspect
of
organic
synthesis.
This
review
focuses
on
the
recent
advancements
in
harnessing
photoinduced
processes
for
formation
carbon‐chalcogen
(C−O,
C−S,
C−Se,
and
C−Te)
bonds
under
catalyst‐free
conditions.
These
pathways
typically
involve
either
radical
mechanism
or
creation
electron‐donor‐acceptor
(EDA)
complexes.
The
explores
intricacies
underlying
mechanisms,
discusses
limitations,
evaluates
applicability
various
methodologies
this
field.
Notably,
photocatalyst
transition
metal‐free
photochemical
reactions
offer
effective
alternatives
to
enhance
sustainability
research
area.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
11(43), P. 15674 - 15684
Published: Oct. 15, 2023
Photochemical
activation
using
red
or
near-infrared
light
has
recently
emerged
as
a
potential
remedy
for
solving
fundamental
issues
in
photochemistry
such
selectivity
and
scale
up.
However,
this
is
particularly
challenging
the
case
of
photooxidation
chemistry
due
to
low
resistance
photobleaching
poor
solubility
photocatalysts
absorbing
region
electromagnetic
spectrum.
In
study,
we
report
use
commercially
available
Si-phthalocyanines
robust
environmentally
friendly
class
soluble
photosensitizers
activated
under
light.
Interestingly,
while
exhibit
lower
singlet
oxygen
generation
(ϕΔ)
quantum
yields
compared
classical
photosensitizers,
their
high
stability
enables
us
achieve
comparable
efficiencies
at
ultralow
catalytic
loadings
(ppb
range).
This
unique
feature
provides
performances
range
photooxidative
processes
substrate
concentrations
ultimately
leading
safe
efficient
solvent-free
continuous
flow
applied
multigram-scale
synthesis.
Catalysis Science & Technology,
Journal Year:
2024,
Volume and Issue:
14(19), P. 5755 - 5763
Published: Jan. 1, 2024
A
green
and
scalable
heterogeneous
photocatalysis
platform
is
efficiently
established
for
multigram
juglone
production
using
photomicroreactors,
which
are
at
the
forefront
of
sustainable
flow
chemistry.
Toxicological Sciences,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 7, 2024
There
is
a
variety
of
electrophiles
in
the
environment.
In
addition,
there
are
precursor
chemicals
that
undergo
metabolic
activation
by
enzymes
and
conversion
to
body.
Although
covalently
bind
protein
nucleophiles,
they
also
form
adducts
associated
with
adaptive
or
toxic
responses.
Low
molecular
weight
compounds
containing
sulfur
capable
blocking
such
adduct
formation
capturing
electrophiles.
this
review,
we
present
out
findings
on
capture
inactivation
1)
intracellular
glutathione,
2)
reactive
species
3)
extracellular
cysteine
(formed
during
production
adducts).
These
actions
not
only
substantially
suppress
electrophilic
activity
but
regulate
formation.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(43)
Published: Nov. 9, 2024
Abstract
The
discovery
of
new
environmentally
friendly
recyclable
photosensitizers
is
key
to
develop
future
applications
in
photooxidation
chemistry.
We
report
here
the
evaluation
a
set
differently
substituted
biobased
hydroxyanthraquinones
context
visible
light
mediated
singlet
oxygen
(
1
O
2
)
photochemistry.
This
class
compounds
efficiently
immobilized
on
alumina
supports,
which
offers
simple
way
removing
them
from
reaction
mixture
downstream.
An
integrated
process
using
flow
reactor
with
fixed
catalytic
bed
also
evaluated
and
its
performance
compared
homogeneous
conditions.
