Tetrahedron, Journal Year: 2024, Volume and Issue: 159, P. 134015 - 134015
Published: May 3, 2024
Language: Английский
Tetrahedron, Journal Year: 2024, Volume and Issue: 159, P. 134015 - 134015
Published: May 3, 2024
Language: Английский
The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: April 30, 2025
A photocatalytic method for the synthesis of N-Mannich bases has been developed through C(sp3)-H/N-H cross-dehydrogenative coupling N,N-dimethylanilines with amides/imides. This process utilizes 2,4,6-triphenylpyrylium tetrafluoroborate (TPT) as photocatalyst and is conducted at ambient temperature atmospheric air. Various aromatic, heteroaromatic aliphatic (cyclic) amides, well imides were successfully employed, yielding moderate to good results. Preliminary mechanistic isotope-labeling studies indicate that reaction likely proceeds via a single electron transfer pathway involves an α-aminoalkyl radical intermediate.
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: May 1, 2025
An iodine-catalyzed aerobic oxidation reaction of C(sp3)-H bonds was established at room temperature. In this transformation, iodine acts as a Lewis acid catalyst, and the pyridine moiety in substrate plays crucial role. Under optimum conditions, picolyl ketone substrates were smoothly transformed into corresponding 1,2-dicarbonyl compounds, subsequent introduction 1,2-diaminobenzenes mixture led to formation various quinoxaline derivatives. This synthetic process does not use transition metals also features mild operational simplicity, gram-scale synthesis.
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(5), P. 3481 - 3490
Published: Feb. 21, 2024
We present a direct δ-amination reaction of sp
Language: Английский
Citations
2Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(11), P. 2602 - 2606
Published: April 13, 2024
Abstract This study reports the copper‐catalyzed α‐indolmethylation of 2‐pyridylacetates with 3‐indoleacetic acids. reaction offers an approach to generating alkylideneindolenine electrophiles via oxidative decarboxylation The developed system demonstrates good versatility, extending beyond indolmethylation include activated esters and nitroalkanes. Moreover, a biological evaluation revealed that several products exhibited antiproliferative activity against different cancer cell lines.
Language: Английский
Citations
1The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(21), P. 16049 - 16054
Published: Oct. 21, 2024
The synthesis of polyfunctionalized pyrroles via the cascade reactions 1,3-dicarbonyl compounds and two molecules ethyl secondary amines has been realized simple iodine catalysis in presence Dess-Martin periodinane (DMP). formation target pyrrole products involves one new C-C C-N bonds major functionalization six C(sp
Language: Английский
Citations
0Published: Jan. 1, 2024
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI
Language: Английский
Citations
0Tetrahedron, Journal Year: 2024, Volume and Issue: 159, P. 134015 - 134015
Published: May 3, 2024
Language: Английский
Citations
0