Multicomponent Synthesis of 3(2H)‐Furanones Initiated by Copper(II)‐Catalyzed Alkyne‐Carbonyl Cross Metathesis DOI
Zhenjie Su, Shaozhong Wang

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(48)

Published: Aug. 2, 2024

Abstract The cooperative Lewis and Brønsted acid catalysis makes convergent synthesis of 3(2 H )‐furanones through a three‐component coupling 1,3‐diynes, alkyl glyoxylates water. Control experiments support that acid‐catalyzed highly chemo‐, regio‐ stereoselective alkyne‐carbonyl metathesis 1,3‐diynes might be the initial step this multicomponent annulation. Further chemo‐ regioselective hydration product subsequent oxa‐Michael addition promoted by results in formation two C−O bonds five‐membered oxygen heterocycle.

Language: Английский

Synthesis of 5-Amino-3(2H)-furanones via S-Methylation/Intramolecular Cyclization of γ-Sulfanylamides DOI
Sho Inagaki,

Riko Omichi,

Kei Yamazaki

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(10), P. 6770 - 6782

Published: May 1, 2024

The

Language: Английский

Citations

0
Multicomponent Synthesis of 3(2H)‐Furanones Initiated by Copper(II)‐Catalyzed Alkyne‐Carbonyl Cross Metathesis DOI
Zhenjie Su, Shaozhong Wang

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(48)

Published: Aug. 2, 2024

Abstract The cooperative Lewis and Brønsted acid catalysis makes convergent synthesis of 3(2 H )‐furanones through a three‐component coupling 1,3‐diynes, alkyl glyoxylates water. Control experiments support that acid‐catalyzed highly chemo‐, regio‐ stereoselective alkyne‐carbonyl metathesis 1,3‐diynes might be the initial step this multicomponent annulation. Further chemo‐ regioselective hydration product subsequent oxa‐Michael addition promoted by results in formation two C−O bonds five‐membered oxygen heterocycle.

Language: Английский

Citations

0