Recent Progress on Organic Electron Donors (OEDs) Enabled Radical Reactions DOI Open Access
Yu Shao, Xiaodong Jia

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Abstract Over the past few decades, organic transformations facilitated by small molecules have witnessed considerable advancements. Small been widely applied to construction of various skeletons. However, reduction as one fundamental reactions is generally initiated metal‐containing reducing agents, although initial progress electron donors (OEDs) enabled reductive cleavage some chemical bonds had achieved in 1990s. Due their structural diversity and tunability, OEDs can overcome limitations metal‐based such low selectivity poor functional group tolerance well environmental problems caused substantial inorganic waste after reactions. Building on a brief historical overview OED research, this review focuses rencent advancements promoted radical It covers C−X (X=C, O, N etc.) single bonds, cyclization, intermolecular addition unsaturated coupling, functionalization aromatics, C−H bond activation. Additionally, mechanistic insights typical are highlighted for understanding reaction mode involving OEDs.

Language: Английский

Organic Bases as the Organic Electron Donors (OED) Promoted Reductive Coupling of Diarylhalomethanes: Halogens Controlled Construction of Tetraarylethylenes and Tetraarylethanes DOI

Tong Li,

Jie Mao, Shuwei Zhang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13101 - 13109

Published: Sept. 2, 2024

Using the organic base as electron donors, reductive coupling of diaryhalomethanes was smoothly achieved under transition-metal-free reaction conditions, giving a series synthetically important tetraarylethylenes and tetraarylethanes in high yields. The mechanistic study revealed that bases acting donor initiated generation radical intermediate, realizing construction tetraarylethylene tetraarylethane skeletons.

Language: Английский

Citations

1
Recent Progress on Organic Electron Donors (OEDs) Enabled Radical Reactions DOI Open Access
Yu Shao, Xiaodong Jia

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Abstract Over the past few decades, organic transformations facilitated by small molecules have witnessed considerable advancements. Small been widely applied to construction of various skeletons. However, reduction as one fundamental reactions is generally initiated metal‐containing reducing agents, although initial progress electron donors (OEDs) enabled reductive cleavage some chemical bonds had achieved in 1990s. Due their structural diversity and tunability, OEDs can overcome limitations metal‐based such low selectivity poor functional group tolerance well environmental problems caused substantial inorganic waste after reactions. Building on a brief historical overview OED research, this review focuses rencent advancements promoted radical It covers C−X (X=C, O, N etc.) single bonds, cyclization, intermolecular addition unsaturated coupling, functionalization aromatics, C−H bond activation. Additionally, mechanistic insights typical are highlighted for understanding reaction mode involving OEDs.

Language: Английский

Citations

1